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Index > Protein center > Klrb1c(Gene name) > Mouse
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  • Klrb1c (Gene name),
  • Killer cell lectin-like receptor subfamily B member 1C (Protein name ),  KLRBC_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Klrb1c(Ly55c;Nkrp1c);
    Protein name:
    Killer cell lectin-like receptor subfamily B member 1C;
    Alternative:
    Lymphocyte antigen 55c(Ly-55c);CD161 antigen-like family member C;NKR-P1.9;NK1.1;Natural killer cell surface protein P1-40(NKR-P1 40);NKR-P1C;
    CD:
    CD161c;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer; disulfide-linked. Interacts with tyrosine kinase LCK.
    Function:
    Plays a stimulatory role on natural killer (NK) cells cytotoxicity. Activation by cross-linking of the receptor induces Ca(2+) mobilization and interferon-gamma production.
    Subcellular Location:
    Membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    223
    Sequence:
    50:
    MDTASIYLGL | KPPRTLGAWH | ESPPSLPPDA | CRCPRSHRLA | LKLSCAGLIL | 
    100:
    LVLTLIGMSV | LVRVLVQKPS | REKCCVFIQE | NLNKTTDCSV | NLECPQDWLL | 
    150:
    HRDKCFHVSQ | VSNTWEEGQA | DCGRKGATLL | LIQDQEELRF | LLDSIKEKYN | 
    200:
    SFWIGLRFTL | PDMNWKWING | TTFNSDVLKI | TGVTENGSCA | SILGDKVTPE | 
    223:
    SCASDNRWIC | QKELNHETPS | NDS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    KEGG:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Killer cell lectin-like receptor subfamily B member 1C
    CLIA Kit for Mouse Killer cell lectin-like receptor subfamily B member 1C
    Polyclonal Antibody for Mouse Killer cell lectin-like receptor subfamily B member 1C
    Monoclonal Antibody for Mouse Killer cell lectin-like receptor subfamily B member 1C
    Protein for Mouse Killer cell lectin-like receptor subfamily B member 1C

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Mouse NKR-P1. A family of genes selectively coexpressed in adherent lymphokine-activated killer cells."
      Giorda R. , Trucco M.
      J. Immunol.147:1701-1708(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
    2. 2.
      "Molecular cloning of the NK1.1 antigen, a member of the NKR-P1 family of natural killer cell activation molecules."
      Ryan J.C. , Turck J. , Niemi E.C. , Yokoyama W.M. , Seaman W.E.
      J. Immunol.149:1631-1635(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      strain: C57BL/6J.
    3. 3.
      "The NKR-P1B gene product is an inhibitory receptor on SJL/J NK cells."
      Kung S.K.P. , Su R.-C. , Shannon J. , Miller R.G.
      J. Immunol.162:5876-5887(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      strain: C57BL/6.
    4. 4.
      "Analysis of a 1-Mb BAC contig overlapping the mouse Nkrp1 cluster of genes: cloning of three new Nkrp1 members, Nkrp1d, Nkrp1e, and Nkrp1f."
      Plougastel B. , Matsumoto K. , Dubbelde C. , Yokoyama W.M.
      Immunogenetics53:592-598(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: C57BL/6J.
    5. 5.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6J.
      tissue: Thymus.
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Heart.
      tissue: Lung.
    7. 7.
      "Identification of upstream cis-acting regulatory elements controlling lineage-specific expression of the mouse NK cell activation receptor, NKR-P1C."
      Ljutic B. , Carlyle J.R. , Zuniga-Pfluecker J.C.
      J. Biol. Chem.278:31909-31917(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    8. 8.
      "Functional requirements for signaling through the stimulatory and inhibitory mouse NKR-P1 (CD161) NK cell receptors."
      Ljutic B. , Carlyle J.R. , Filipp D. , Nakagawa R. , Julius M. , Zuniga-Pfluecker J.C.
      J. Immunol.174:4789-4796(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH LCK;MUTAGENESIS OF TYR-7 AND CYS-31;FUNCTION
    9. 9.
      "Molecular and genetic basis for strain-dependent NK1.1 alloreactivity of mouse NK cells."
      Carlyle J.R. , Mesci A. , Ljutic B. , Belanger S. , Tai L.-H. , Rousselle E. , Troke A.D. , Proteau M.-F. , Makrigiannis A.P.
      J. Immunol.176:7511-7524(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ANTI-NK1.1 MONOCLONAL ANTIBODY
      strain: BALB/c.
      tissue: Spleen.
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