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Index > Protein center > KLRF2(Gene name) > Human
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  • KLRF2 (Gene name),
  • Killer cell lectin-like receptor subfamily F member 2 (Protein name ),  KLRF2_HUMAN from NCBI database.
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  • General Annotation
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  • Gene name:
    KLRF2;
    Protein name:
    Killer cell lectin-like receptor subfamily F member 2(Lectin-like receptor F2);
    Alternative:
    Activating coreceptor NKp65;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer; non disulfide-linked. Interacts with CLEC2A.
    Function:
    C-type lectin-like receptor involved in natural killer cell mediated cytotoxicity and cytokine secretion in keratinocytes via its interaction with CLEC2A.
    Subcellular Location:
    Cell membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    207
    Sequence:
    50:
    MENEDGYMTL | SFKNRCKSKQ | KSKDFSLYPQ | YYCLLLIFGC | IVILIFIMTG | 
    100:
    IDLKFWHKKM | DFSQNVNVSS | LSGHNYLCPN | DWLLNEGKCY | WFSTSFKTWK | 
    150:
    ESQRDCTQLQ | AHLLVIQNLD | ELEFIQNSLK | PGHFGWIGLY | VTFQGNLWMW | 
    200:
    IDEHFLVPEL | FSVIGPTDDR | SCAVITGNWV | YSEDCSSTFK | GICQRDAILT | 
    207:
    HNGTSGV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Lectin-like receptor F2
    CLIA Kit for Human Lectin-like receptor F2
    Polyclonal Antibody for Human Lectin-like receptor F2
    Monoclonal Antibody for Human Lectin-like receptor F2
    Protein for Human Lectin-like receptor F2

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Interaction of C-type lectin-like receptors NKp65 and KACL facilitates dedicated immune recognition of human keratinocytes."
      Spreu J. , Kuttruff S. , Stejfova V. , Dennehy K.M. , Schittek B. , Steinle A.
      Proc. Natl. Acad. Sci. U.S.A.107:5100-5105(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;SUBUNIT;GLYCOSYLATION;INTERACTION WITH CLEC2A;MUTAGENESIS OF TYR-7
    2. 2.
      "The finished DNA sequence of human chromosome 12."
      Scherer S.E. , Muzny D.M. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , Jackson A. , Khan Z.M. , Kovar-Smith C. , Lewis L.R. , more...
      Nature440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "Structure of NKp65 bound to its keratinocyte ligand reveals basis for genetically linked recognition in natural killer gene complex."
      Li Y. , Wang Q. , Chen S. , Brown P.H. , Mariuzza R.A.
      Proc. Natl. Acad. Sci. U.S.A.110:11505-11510(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS) OF 63-207 IN COMPLEX WITH CLEC2A;INTERACTION WITH CLEC2A;DISULFIDE BONDS
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