Klrg1 ELISA Kit for Mouse(Mus musculus) | EIAab.comKlrg1 ELISA Kit for Mouse(Mus musculus)

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Klrg1 (Gene name),

Killer cell lectin-like receptor subfamily G member 1 (Protein name ), KLRG1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Klrg1(Mafa);

Protein name:

Killer cell lectin-like receptor subfamily G member 1;

Alternative:

Mast cell function-associated antigen 2F1;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Forms monomer and homodimer; disulfide-linked (By similarity). Interacts (via ITIM motif) with PTPN11 and INPP5D.

Function:

Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.

Subcellular Location:

Cell membrane Single-pass type II membrane protein

Protein Attributes:

Sequence length:

188

Sequence:

50:

100:

150:

188:

LRILTNSLIQ | RCGAIHRNGL | QASSCEVALQ | WICKKVLY

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

O88713

Pfam:

PF00059

String:

O88713

UniGene:

Mm.20434

KEGG:

mmu:50928

STRING:

10090.ENSMUSP00000032207

Uniprot:

O88713

FOR

ELISA Kit for Mouse Killer cell lectin-like receptor subfamily G member 1

CLIA Kit for Mouse Killer cell lectin-like receptor subfamily G member 1

Polyclonal Antibody for Mouse Killer cell lectin-like receptor subfamily G member 1

Monoclonal Antibody for Mouse Killer cell lectin-like receptor subfamily G member 1

Protein for Mouse Killer cell lectin-like receptor subfamily G member 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"2F1 antigen, the mouse homolog of the rat 'mast cell function-associated antigen', is a lectin-like type II transmembrane receptor expressed by natural killer cells."
Hanke T. , Corral L. , Vance R.E. , Raulet D.H.
Eur. J. Immunol.28:4409-4417(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
strain: CB-17/SCID.
2.

"Virus-activated CD8 T cells and lymphokine-activated NK cells express the mast cell function-associated antigen, an inhibitory C-type lectin."
Blaser C. , Kaufmann M. , Pircher H.
J. Immunol.161:6451-6454(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
3.

"Genomic structure, alternative splicing, and physical mapping of the killer cell lectin-like receptor G1 gene (KLRG1), the mouse homologue of MAFA."
Voehringer D. , Kaufmann M. , Pircher H.
Immunogenetics52:206-211(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain: 129/SvEvTacfBr.
tissue: Spleen.
4.

"Viral infections induce abundant numbers of senescent CD8 T cells."
Voehringer D. , Blaser C. , Brawand P. , Raulet D.H. , Hanke T. , Pircher H.
J. Immunol.167:4838-4843(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION BY VIRAL INFECTIONS
5.

"Inhibitory functions of the killer cell lectin-like receptor G1 molecule during the activation of mouse NK cells."
Robbins S.H. , Nguyen K.B. , Takahashi N. , Mikayama T. , Biron C.A. , Brossay L.
J. Immunol.168:2585-2589(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION BY PATHOGENS INFECTIONS
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
7.

"Identification of E-cadherin as a ligand for the murine killer cell lectin-like receptor G1."
Gruendemann C. , Bauer M. , Schweier O. , von Oppen N. , Laessing U. , Saudan P. , Becker K.-F. , Karp K. , Hanke T. , Bachmann M.F. , Pircher H.
J. Immunol.176:1311-1315(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: LIGAND-BINDING
8.

"KLRG1 binds cadherins and preferentially associates with SHIP-1."
Tessmer M.S. , Fugere C. , Stevenaert F. , Naidenko O.V. , Chong H.J. , Leclercq G. , Brossay L.
Int. Immunol.19:391-400(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: LIGAND-BINDING;INTERACTION WITH PTPN11 AND INPP5D;MUTAGENESIS OF SER-5; TYR-7; SER-8 AND LEU-10
9.

"Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition."
Li Y. , Hofmann M. , Wang Q. , Teng L. , Chlewicki L.K. , Pircher H. , Mariuzza R.A.
Immunity31:35-46(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 75-188 ALONE AND IN COMPLEX WITH HUMAN E-CADHERIN;FUNCTION;SUBCELLULAR LOCATION;DISULFIDE BONDS

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