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Index > Protein center > PRKCA(Gene name) > Bovine
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  • PRKCA (Gene name),
  • Protein kinase C alpha type (Protein name ),  KPCA_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    PRKCA;
    Protein name:
    Protein kinase C alpha type(PKC-A;PKC-alpha);
    Alternative:

    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Interacts with ADAP1/CENTA1, CSPG4 and PRKCABP. Binds to SDPR in the presence of phosphatidylserine (By similarity). Interacts with PICK1 (via PDZ domain) (By similarity). Interacts with TRIM41 (By similarity). Recruited in a circadian manner into a nuclear complex which also includes BMAL1 and GNB2L1/RACK1.
    Function:
    PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
    Subcellular Location:
    Cytoplasm Cell membrane Peripheral membrane protein Nucleus
    Protein Attributes:
    Sequence length:
    672
    Sequence:
    50:
    MADVFPAAEP | AAPQDVANRF | ARKGALRQKN | VHEVKNHRFI | ARFFKQPTFC | 
    100:
    SHCTDFIWGF | GKQGFQCQVC | CFVVHKRCHE | FVTFSCPGAD | KGPDTDDPRS | 
    150:
    KHKFKIHTYG | SPTFCDHCGS | LLYGLIHQGM | KCDTCDMNVH | KQCVINVPSL | 
    200:
    CGMDHTEKRG | RIYLKAEVTD | EKLHVTVRDA | KNLIPMDPNG | LSDPYVKLKL | 
    250:
    IPDPKNESKQ | KTKTIRSTLN | PRWDESFTFK | LKPSDKDRRL | SEEIWDWDRT | 
    300:
    TRNDFMGSLS | FGVSELMKMP | ASGWYKLLNQ | EEGEYYNVPI | PEGDEEGNVE | 
    350:
    LRQKFEKAKL | GPAGNKVISP | SEDRRQPSNN | LDRVKLTDFN | FLMVLGKGSF | 
    400:
    GKVMLADRKG | TEELYAIKIL | KKDVVIQDDD | VECTMVEKRV | LALLDKPPFL | 
    450:
    TQLHSCFQTV | DRLYFVMEYV | NGGDLMYHIQ | QVGKFKEPQA | VFYAAEISIG | 
    500:
    LFFLHKRGII | YRDLKLDNVM | LDSEGHIKIA | DFGMCKEHMM | DGVTTRTFCG | 
    550:
    TPDYIAPEII | AYQPYGKSVD | WWAYGVLLYE | MLAGQPPFDG | EDEDELFQSI | 
    600:
    MEHNVSYPKS | LSKEAVSICK | GLMTKHPGKR | LGCGPEGERD | VREHAFFRRI | 
    650:
    DWEKLENREI | QPPFKPKVCG | KGAENFDKFF | TRGQPVLTPP | DQLVIANIDQ | 
    672:
    SDFEGFSYVN | PQFVHPILQS | AV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    String:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine PKC-A
    Cat.:
    E1380m
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    MSDS:
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    96T
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    ELISA Kit for Bovine PKC-A
    Cat.:
    E1380b
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    96T
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    ELISA Kit for Bovine PKC-A
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    E1380r
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    Please sign in first.
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    96T
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    ELISA Kit for Bovine PKC-A
    Cat.:
    E1380h
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine PKC-A
    MSDS:
    Please sign in first.
    CLIA Kit for Bovine PKC-A
    Cat.:
    U1380b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine PKC-A
    Cat.:
    U1380h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Bovine PKC-A
    MSDS:
    Please sign in first.
    CLIA Kit for Bovine PKC-A
    Cat.:
    U1380r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine PKC-A
    Cat.:
    U1380m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Bovine PKC-A
    Polyclonal Antibody for Bovine PKC-A
    Cat.:
    P1380Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine PKC-A
    Cat.:
    P1380Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine PKC-A
    Polyclonal Antibody for Bovine PKC-A
    Cat.:
    P1380Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Bovine PKC-A
    Monoclonal Antibody for Bovine PKC-A
    Monoclonal Antibody for Bovine PKC-A
    Monoclonal Antibody for Bovine PKC-A
    Monoclonal Antibody for Bovine PKC-A
    Protein for Bovine PKC-A
    Protein for Bovine PKC-A
    Protein for Bovine PKC-A
    Protein for Bovine PKC-A
    Protein for Bovine PKC-A

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The complete primary structure of protein kinase C -- the major phorbol ester receptor."
      Parker P.J. , Coussens L. , Totty N. , Rhee L. , Young S. , Chen E. , Stabel S. , Waterfield M.D. , Ullrich A.
      Science233:853-859(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    2. 2.
      "The molecular heterogeneity of protein kinase C and its implications for cellular regulation."
      Nishizuka Y.
      Nature334:661-665(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    3. 3.
      "Identification of the phosphorylated region responsible for the permissive activation of protein kinase C."
      Cazaubon S.M. , Parker P.J.
      J. Biol. Chem.268:17559-17563(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF THR-494; THR-495 AND THR-497;PHOSPHORYLATION AT THR-494; THR-495 AND THR-497
    4. 4.
      "Phosphorylation of protein kinase C-alpha on serine 657 controls the accumulation of active enzyme and contributes to its phosphatase-resistant state."
      Bornancin F. , Parker P.J.
      J. Biol. Chem.272:3544-3549(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-657
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