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Index > Protein center > KRTAP10-5(Gene name) > Human
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  • KRTAP10-5 (Gene name),
  • Keratin-associated protein 10-5 (Protein name ),  KR105_HUMAN from NCBI database.
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  • General Annotation
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    • Gene name:
    KRTAP10-5(KAP10.5;KAP18-5;KRTAP10.5;KRTAP18-5;KRTAP18.5);
    Protein name:
    Keratin-associated protein 10-5;
    Alternative:
    Keratin-associated protein 10.5;High sulfur keratin-associated protein 10.5;Keratin-associated protein 18.5;Keratin-associated protein 18-5;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with hair keratins.
    Function:
    In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    271
    Sequence:
    50:
    MAACTMSVCS | SACSDSWRVD | DCPESCCEPP | CGTAPCLTLV | CTPVSCVSSP | 
    100:
    CCQAACEPSP | CQSGCTSSCT | PSCCQPACCA | SSPCQQACCV | PVCCKPVCCL | 
    150:
    PTCSKDSSSC | CQQSSCQPTC | CASSSCQQSC | CVPVCCKPVC | CVPTCSEDSS | 
    200:
    SCCQHSSCQP | TCCTSSPCQQ | SCYVPVCCKP | VCFKPICCVP | VCSGASTSCC | 
    250:
    QQSSCQPACC | TTSCCRPSSS | VSLLCRPICR | PACCVPISSC | CAPASSYQAS | 
    271:
    CCRPASCVSL | LCRPACSRLA | C
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Hs.688629
    STRING:
    9606.ENSP00000383223
    KEGG:
    hsa:386680
    Uniprot:
    P60370
     
    FOR
    ELISA Kit for Human Keratin-associated protein 10-5
    CLIA Kit for Human Keratin-associated protein 10-5
    Polyclonal Antibody for Human Keratin-associated protein 10-5
    Monoclonal Antibody for Human Keratin-associated protein 10-5
    Protein for Human Keratin-associated protein 10-5

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    Linearity
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    References
    1. 1.
      "A cluster of 21 keratin-associated protein genes within introns of another gene on human chromosome 21q22.3."
      Shibuya K. , Obayashi I. , Asakawa S. , Minoshima S. , Kudoh J. , Shimizu N.
      Genomics83:679-693(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;VARIANTS LEU-235 AND PRO-268
      tissue: Hair root.
    2. 2.
      "The DNA sequence of human chromosome 21."
      Hattori M. , Fujiyama A. , Taylor T.D. , Watanabe H. , Yada T. , Park H.-S. , Toyoda A. , Ishii K. , Totoki Y. , Choi D.-K. , Groner Y. , Soeda E. , Ohki M. , Takagi T. , Sakaki Y. , Taudien S. , Blechschmidt K. , Polley A. , more...
      Nature405:311-319(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ASN-20
    4. 4.
      "Hair keratin associated proteins: characterization of a second high sulfur KAP gene domain on human chromosome 21."
      Rogers M.A. , Langbein L. , Winter H. , Beckmann I. , Praetzel S. , Schweizer J.
      J. Invest. Dermatol.122:147-158(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 261-271;TISSUE SPECIFICITY
      tissue: Scalp.
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