Gene name:
KRTAP10-12(KAP10.12;KAP18-12;KRTAP10.12;KRTAP18-12;KRTAP18.12);
Protein name:
Keratin-associated protein 10-12;
Alternative:
Keratin-associated protein 10.12;High sulfur keratin-associated protein 10.12;Keratin-associated protein 18.12;Keratin-associated protein 18-12;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with hair keratins.
Function:
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Subcellular Location:
N/A
Protein Attributes:
50:
MSVCSSDLSY | GSRVCLPGSC | DSCSDSWQVD | DCPESCCEPP | CCAPAPCLSL |
100:
VCTPVSRVSS | PCCRVTCEPS | PCQSGCTSSC | TPSCCQQSSC | QPACCTSSPC |
150:
QQACCVPVCC | KTVCCKPVCC | MPVCCGPSSS | CCQQSSCQPA | CCISSPCQQS |
200:
CCVPVCCKPI | CCVPVCSGAS | SLCCQQSSCQ | PACCTTSCCR | PSSSVSLLCR |
245:
PVCRPARRVP | VPSCCVPTSS | CQPSCGRLAS | CGSLLCRPTC | SRLAC
Vaild Sequence:
Related Databases
Uniprot:
