Gene name:
    KREMEN1 (KREMEN;KRM1) ;
    
 
    Protein name:
    Kremen protein 1 ;
    
    Alternative:
    
    Kringle domain-containing transmembrane protein 1 ;Dickkopf receptor ;Kringle-containing protein marking the eye and the nose ;
    
    
 
    Organism:
        
        
        
        
        
        
    
        Human  (Homo sapiens).  
    
 
General Annotation
    Function:
    Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling.
    
 
    
        
        Subcellular Location:
        
    
     
     
      Membrane  
      Single-pass type I membrane protein 
     
  
    
 
    
    Protein Attributes:
    
    50:
    MAPPAARLAL |  LSAAALTLAA |  RPAPSPGLGP |  ECFTANGADY |  RGTQNWTALQ |  
    
 
    100:
    GGKPCLFWNE |  TFQHPYNTLK |  YPNGEGGLGE |  HNYCRNPDGD |  VSPWCYVAEH |  
    
 
    150:
    EDGVYWKYCE |  IPACQMPGNL |  GCYKDHGNPP |  PLTGTSKTSN |  KLTIQTCISF |  
    
 
    200:
    CRSQRFKFAG |  MESGYACFCG |  NNPDYWKYGE |  AASTECNSVC |  FGDHTQPCGG |  
    
 
    250:
    DGRIILFDTL |  VGACGGNYSA |  MSSVVYSPDF |  PDTYATGRVC |  YWTIRVPGAS |  
    
 
    300:
    HIHFSFPLFD |  IRDSADMVEL |  LDGYTHRVLA |  RFHGRSRPPL |  SFNVSLDFVI |  
    
 
    350:
    LYFFSDRINQ |  AQGFAVLYQA |  VKEELPQERP |  AVNQTVAEVI |  TEQANLSVSA |  
    
 
    400:
    ARSSKVLYVI |  TTSPSHPPQT |  VPGSNSWAPP |  MGAGSHRVEG |  WTVYGLATLL |  
    
 
    450:
    ILTVTAIVAK |  ILLHVTFKSH |  RVPASGDLRD |  CHQPGTSGEI |  WSIFYKPSTS |  
    
 
    473:
    ISIFKKKLKG |  QSQQDDRNPL |  VSD
    
 
      Vaild Sequence:
    
 
Related Databases
Uniprot:
 
 
    
        
        ELISA Kit
         
        
        CLIA Kit
         
        
        Polyclonal Antibody
         
        
        Monoclonal Antibody
         
        
        Protein
         
        
     
FOR
    
        
        Rat
         
        
        Human
         
        
        Mouse
         
        
     
    
        ELISA Kit for Human Kremen protein 1
        
     
    
    
    
    
    
    
 
    
        ELISA Kit for Human Kremen protein 1
        
     
    
    
    
    
    
    
 
    
        ELISA Kit for Human Kremen protein 1
        
     
    
    
    
    
    
    
 
    
        CLIA Kit for Human Kremen protein 1
        
     
    
    
    
    
    
    
 
    
        CLIA Kit for Human Kremen protein 1
        
     
    
    
    
    
    
    
 
    
        CLIA Kit for Human Kremen protein 1
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human Kremen protein 1
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human Kremen protein 1
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human Kremen protein 1
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human Kremen protein 1
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human Kremen protein 1
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human Kremen protein 1
        
     
    
    
    
    
    
    
 
    
        Protein for Human Kremen protein 1
        
     
    
    
    
    
    
    
 
    
        Protein for Human Kremen protein 1
        
     
    
    
    
    
    
    
 
    
        Protein for Human Kremen protein 1
        
     
    
    
    
    
    
    
 
 
 
 
 
 
 
 
    R&D Technical Data
    
    
    
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    Precision
    
    
    
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    Recovery
    
    
    
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    Linearity
    
    
    
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    References
    
    
        
            
        
            
                1.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1) 
                    
                    
                 
             
         
            
        
            
                2.
                
                    
                        
                            "Complete sequencing and characterization of 21,243 full-length human cDNAs." 
                        
                        
                            Ota T. 
                        ,
                            
Suzuki Y. 
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Nishikawa T. 
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Otsuki T. 
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Wakamatsu A. 
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Nishi T. 
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Shibahara T. 
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                              more...   
                             
                        
                        
                        
                            Nat. Genet.36:40-45(2004)
                         
                        
                        
                        [
PubMed ]
                        [
Europe PMC ]
                        [
Abstract ]
                        
                    
 
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2) 
                    
                    
                 
             
         
            
        
            
                3.
                
                    
                        
                            "The DNA sequence of human chromosome 22." 
                        
                        
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                            Lai H. 
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                            Lewis J. 
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                            Lin S.-P. 
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                            Malaj E. 
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                            Nguyen T. 
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                            Phan S. 
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                            Qi S. 
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                            Ray L. 
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                            Ren Q. 
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                            Shaull S. 
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                              more...   
                             
                        
                        
                        
                            Nature402:489-495(1999)
                         
                        
                        
                        [
PubMed ]
                        [
Europe PMC ]
                        [
Abstract ]
                        
                    
 
                    
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                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] 
                    
                    
                 
             
         
            
        
            
                4.
                
                    
                        
                        
                            Mural R.J. 
                        ,
                            
Istrail S. 
                        ,
                            
Sutton G.G. 
                        ,
                            
Florea L. 
                        ,
                            
Halpern A.L. 
                        ,
                            
Mobarry C.M. 
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Lippert R. 
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Walenz B. 
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Shatkay H. 
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Dew I. 
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Miller J.R. 
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Flanigan M.J. 
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Edwards N.J. 
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Bolanos R. 
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Fasulo D. 
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Halldorsson B.V. 
                        ,
                            
Hannenhalli S. 
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Turner R. 
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                            Yooseph S. 
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                            Lu F. 
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                            Zheng X.H. 
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                            Zhong F. 
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                              more...   
                             
                        
                        
                            Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
                        
                        
                    
 
                    
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                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] 
                    
                    
                 
             
         
            
        
            
                5.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3) 
                    
                    
                    tissue :
                    
Eye .