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Index > Protein center > TK1(Gene name) > Human
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  • TK1 (Gene name),
  • Thymidine kinase, cytosolic (Protein name ),  KITH_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    TK1;
    Protein name:
    Thymidine kinase, cytosolic;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homotetramer.
    Function:
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    234
    Sequence:
    50:
    MSCINLPTVL | PGSPSKTRGQ | IQVILGPMFS | GKSTELMRRV | RRFQIAQYKC | 
    100:
    LVIKYAKDTR | YSSSFCTHDR | NTMEALPACL | LRDVAQEALG | VAVIGIDEGQ | 
    150:
    FFPDIVEFCE | AMANAGKTVI | VAALDGTFQR | KPFGAILNLV | PLAESVVKLT | 
    200:
    AVCMECFREA | AYTKRLGTEK | EVEVIGGADK | YHSVCRLCYF | KKASGQPAGP | 
    234:
    DNKENCPVPG | KPGEAVAARK | LFAPQQILQC | SPAN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    UniGene:
    SMR:
    String:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Thymidine kinase, cytosolic
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    E2108h
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    ELISA Kit for Thymidine kinase, cytosolic
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    ELISA Kit for Thymidine kinase, cytosolic
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    ELISA Kit for Thymidine kinase, cytosolic
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    E2108b
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    ELISA Kit for Thymidine kinase, cytosolic
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    E2108c
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    CLIA Kit for Thymidine kinase, cytosolic
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    U2108m
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    CLIA Kit for Thymidine kinase, cytosolic
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    U2108c
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    CLIA Kit for Thymidine kinase, cytosolic
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    U2108b
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    CLIA Kit for Thymidine kinase, cytosolic
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    CLIA Kit for Thymidine kinase, cytosolic
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    Packing:
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    Polyclonal Antibody for Thymidine kinase, cytosolic
    Polyclonal Antibody for Thymidine kinase, cytosolic
    Polyclonal Antibody for Thymidine kinase, cytosolic
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    P2108Rb-h
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    Packing:
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    Polyclonal Antibody for Thymidine kinase, cytosolic
    Polyclonal Antibody for Thymidine kinase, cytosolic
    Cat.:
    P2108Rb-m
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Thymidine kinase, cytosolic
    Monoclonal Antibody for Thymidine kinase, cytosolic
    Monoclonal Antibody for Thymidine kinase, cytosolic
    Monoclonal Antibody for Thymidine kinase, cytosolic
    Monoclonal Antibody for Thymidine kinase, cytosolic
    Protein for Thymidine kinase, cytosolic
    Protein for Thymidine kinase, cytosolic
    Protein for Thymidine kinase, cytosolic
    Protein for Thymidine kinase, cytosolic
    Protein for Thymidine kinase, cytosolic

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Human thymidine kinase gene: molecular cloning and nucleotide sequence of a cDNA expressible in mammalian cells."
      Bradshaw H.D. Jr. , Deininger P.L.
      Mol. Cell. Biol.4:2316-2320(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Sequence, structure and promoter characterization of the human thymidine kinase gene."
      Flemington E. , Bradshaw H.D. Jr. , Traina-Dorge V. , Slagel V. , Deininger P.L.
      Gene52:267-277(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2004-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lymph.
      tissue: Skin.
      tissue: Uterus.
    6. 6.
      "Genetic analysis of the human thymidine kinase gene promoter."
      Kreidberg J.A. , Kelly T.J.
      Mol. Cell. Biol.6:2903-2909(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-22
    7. 7.
      "Serine 13 is the site of mitotic phosphorylation of human thymidine kinase."
      Chang Z.F. , Huang D.Y. , Chi L.M.
      J. Biol. Chem.273:12095-12100(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-13
    8. 8.
      "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
      Beausoleil S.A. , Villen J. , Gerber S.A. , Rush J. , Gygi S.P.
      Nat. Biotechnol.24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-231;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
    11. 11.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2;PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-231;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    13. 13.
      "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
      Bienvenut W.V. , Sumpton D. , Martinez A. , Lilla S. , Espagne C. , Meinnel T. , Giglione C.
      Mol. Cell. Proteomics11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    15. 15.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) OF 1-193 IN COMPLEX WITH ZINC IONS AND TTP;SUBUNIT
    16. 16.
      "Structure of a type II thymidine kinase with bound dTTP."
      Birringer M.S. , Claus M.T. , Folkers G. , Kloer D.P. , Schulz G.E. , Scapozza L.
      FEBS Lett.579:1376-1382(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.83 ANGSTROMS) OF 15-194 IN COMPLEX WITH ZINC IONS AND TTP
    17. 17.
      "Binding of ATP to TK1-like enzymes is associated with a conformational change in the quaternary structure."
      Segura-Pena D. , Lutz S. , Monnerjahn C. , Konrad M. , Lavie A.
      J. Mol. Biol.369:129-141(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) IN COMPLEX WITH ZINC IONS; SUBSTRATE AND ATP ANALOG;SUBUNIT
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