Gene name:
LAMC2 (LAMB2T;LAMNB2) ;
Protein name:
Laminin subunit gamma-2 ;
Alternative:
Epiligrin subunit gamma ;Cell-scattering factor 140 kDa subunit (CSF 140 kDa subunit) ;Kalinin/nicein/epiligrin 100 kDa subunit ;Kalinin subunit gamma ;Laminin B2t chain ;Ladsin 140 kDa subunit ;Large adhesive scatter factor 140 kDa subunit ;Laminin-5 subunit gamma ;Nicein subunit gamma ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Gamma-2 is a subunit of laminin-5 (laminin-332 or epiligrin/kalinin/nicein).
Function:
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Ladsin exerts cell-scattering activity toward a wide variety of cells, including epithelial, endothelial, and fibroblastic cells.
Subcellular Location:
Secreted
extracellular space
extracellular matrix
basement membrane
Major component.
Protein Attributes:
50:
MPALWLGCCL | CFSLLLPAAR | ATSRREVCDC | NGKSRQCIFD | RELHRQTGNG |
100:
FRCLNCNDNT | DGIHCEKCKN | GFYRHRERDR | CLPCNCNSKG | SLSARCDNSG |
150:
RCSCKPGVTG | ARCDRCLPGF | HMLTDAGCTQ | DQRLLDSKCD | CDPAGIAGPC |
200:
DAGRCVCKPA | VTGERCDRCR | SGYYNLDGGN | PEGCTQCFCY | GHSASCRSSA |
250:
EYSVHKITST | FHQDVDGWKA | VQRNGSPAKL | QWSQRHQDVF | SSAQRLDPVY |
300:
FVAPAKFLGN | QQVSYGQSLS | FDYRVDRGGR | HPSAHDVILE | GAGLRITAPL |
350:
MPLGKTLPCG | LTKTYTFRLN | EHPSNNWSPQ | LSYFEYRRLL | RNLTALRIRA |
400:
TYGEYSTGYI | DNVTLISARP | VSGAPAPWVE | QCICPVGYKG | QFCQDCASGY |
450:
KRDSARLGPF | GTCIPCNCQG | GGACDPDTGD | CYSGDENPDI | ECADCPIGFY |
500:
NDPHDPRSCK | PCPCHNGFSC | SVMPETEEVV | CNNCPPGVTG | ARCELCADGY |
550:
FGDPFGEHGP | VRPCQPCQCN | NNVDPSASGN | CDRLTGRCLK | CIHNTAGIYC |
600:
DQCKAGYFGD | PLAPNPADKC | RACNCNPMGS | EPVGCRSDGT | CVCKPGFGGP |
650:
NCEHGAFSCP | ACYNQVKIQM | DQFMQQLQRM | EALISKAQGG | DGVVPDTELE |
700:
GRMQQAEQAL | QDILRDAQIS | EGASRSLGLQ | LAKVRSQENS | YQSRLDDLKM |
750:
TVERVRALGS | QYQNRVRDTH | RLITQMQLSL | AESEASLGNT | NIPASDHYVG |
800:
PNGFKSLAQE | ATRLAESHVE | SASNMEQLTR | ETEDYSKQAL | SLVRKALHEG |
850:
VGSGSGSPDG | AVVQGLVEKL | EKTKSLAQQL | TREATQAEIE | ADRSYQHSLR |
900:
LLDSVSRLQG | VSDQSFQVEE | AKRIKQKADS | LSSLVTRHMD | EFKRTQKNLG |
950:
NWKEEAQQLL | QNGKSGREKS | DQLLSRANLA | KSRAQEALSM | GNATFYEVES |
1000:
ILKNLREFDL | QVDNRKAEAE | EAMKRLSYIS | QKVSDASDKT | QQAERALGSA |
1050:
AADAQRAKNG | AGEALEISSE | IEQEIGSLNL | EANVTADGAL | AMEKGLASLK |
1100:
SEMREVEGEL | ERKELEFDTN | MDAVQMVITE | AQKVDTRAKN | AGVTIQDTLN |
1150:
TLDGLLHLMD | QPLSVDEEGL | VLLEQKLSRA | KTQINSQLRP | MMSELEERAR |
1193:
QQRGHLHLLE | TSIDGILADV | KNLENIRDNL | PPGCYNTQAL | EQQ
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human Laminin subunit gamma-2
ELISA Kit for Human Laminin subunit gamma-2
CLIA Kit for Human Laminin subunit gamma-2
CLIA Kit for Human Laminin subunit gamma-2
Polyclonal Antibody for Human Laminin subunit gamma-2
Polyclonal Antibody for Human Laminin subunit gamma-2
Monoclonal Antibody for Human Laminin subunit gamma-2
Monoclonal Antibody for Human Laminin subunit gamma-2
Protein for Human Laminin subunit gamma-2
Protein for Human Laminin subunit gamma-2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];ALTERNATIVE SPLICING
tissue :
Fibrosarcoma .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 1090-1114
tissue :
Epidermis .
tissue :
Keratinocyte .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];ALTERNATIVE SPLICING
tissue :
Placenta .
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Nature441:315-321(2006)
[
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[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM SHORT)
tissue :
Cerebellum .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE OF 435-449;FUNCTION;HEPARIN-BINDING
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]