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Index > Protein center > LAMC2(Gene name) > Human
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  • LAMC2 (Gene name),
  • Laminin subunit gamma-2 (Protein name ),  LAMC2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    LAMC2(LAMB2T;LAMNB2);
    Protein name:
    Laminin subunit gamma-2;
    Alternative:
    Epiligrin subunit gamma;Cell-scattering factor 140 kDa subunit(CSF 140 kDa subunit);Kalinin/nicein/epiligrin 100 kDa subunit;Kalinin subunit gamma;Laminin B2t chain;Ladsin 140 kDa subunit;Large adhesive scatter factor 140 kDa subunit;Laminin-5 subunit gamma;Nicein subunit gamma;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Gamma-2 is a subunit of laminin-5 (laminin-332 or epiligrin/kalinin/nicein).
    Function:
    Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Ladsin exerts cell-scattering activity toward a wide variety of cells, including epithelial, endothelial, and fibroblastic cells.
    Subcellular Location:
    Secreted extracellular space extracellular matrix basement membrane Major component.
    Protein Attributes:
    Sequence length:
    1193
    Sequence:
    50:
    MPALWLGCCL | CFSLLLPAAR | ATSRREVCDC | NGKSRQCIFD | RELHRQTGNG | 
    100:
    FRCLNCNDNT | DGIHCEKCKN | GFYRHRERDR | CLPCNCNSKG | SLSARCDNSG | 
    150:
    RCSCKPGVTG | ARCDRCLPGF | HMLTDAGCTQ | DQRLLDSKCD | CDPAGIAGPC | 
    200:
    DAGRCVCKPA | VTGERCDRCR | SGYYNLDGGN | PEGCTQCFCY | GHSASCRSSA | 
    250:
    EYSVHKITST | FHQDVDGWKA | VQRNGSPAKL | QWSQRHQDVF | SSAQRLDPVY | 
    300:
    FVAPAKFLGN | QQVSYGQSLS | FDYRVDRGGR | HPSAHDVILE | GAGLRITAPL | 
    350:
    MPLGKTLPCG | LTKTYTFRLN | EHPSNNWSPQ | LSYFEYRRLL | RNLTALRIRA | 
    400:
    TYGEYSTGYI | DNVTLISARP | VSGAPAPWVE | QCICPVGYKG | QFCQDCASGY | 
    450:
    KRDSARLGPF | GTCIPCNCQG | GGACDPDTGD | CYSGDENPDI | ECADCPIGFY | 
    500:
    NDPHDPRSCK | PCPCHNGFSC | SVMPETEEVV | CNNCPPGVTG | ARCELCADGY | 
    550:
    FGDPFGEHGP | VRPCQPCQCN | NNVDPSASGN | CDRLTGRCLK | CIHNTAGIYC | 
    600:
    DQCKAGYFGD | PLAPNPADKC | RACNCNPMGS | EPVGCRSDGT | CVCKPGFGGP | 
    650:
    NCEHGAFSCP | ACYNQVKIQM | DQFMQQLQRM | EALISKAQGG | DGVVPDTELE | 
    700:
    GRMQQAEQAL | QDILRDAQIS | EGASRSLGLQ | LAKVRSQENS | YQSRLDDLKM | 
    750:
    TVERVRALGS | QYQNRVRDTH | RLITQMQLSL | AESEASLGNT | NIPASDHYVG | 
    800:
    PNGFKSLAQE | ATRLAESHVE | SASNMEQLTR | ETEDYSKQAL | SLVRKALHEG | 
    850:
    VGSGSGSPDG | AVVQGLVEKL | EKTKSLAQQL | TREATQAEIE | ADRSYQHSLR | 
    900:
    LLDSVSRLQG | VSDQSFQVEE | AKRIKQKADS | LSSLVTRHMD | EFKRTQKNLG | 
    950:
    NWKEEAQQLL | QNGKSGREKS | DQLLSRANLA | KSRAQEALSM | GNATFYEVES | 
    1000:
    ILKNLREFDL | QVDNRKAEAE | EAMKRLSYIS | QKVSDASDKT | QQAERALGSA | 
    1050:
    AADAQRAKNG | AGEALEISSE | IEQEIGSLNL | EANVTADGAL | AMEKGLASLK | 
    1100:
    SEMREVEGEL | ERKELEFDTN | MDAVQMVITE | AQKVDTRAKN | AGVTIQDTLN | 
    1150:
    TLDGLLHLMD | QPLSVDEEGL | VLLEQKLSRA | KTQINSQLRP | MMSELEERAR | 
    1193:
    QQRGHLHLLE | TSIDGILADV | KNLENIRDNL | PPGCYNTQAL | EQQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    KEGG:
    UniGene:
    MIM:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Laminin subunit gamma-2
    Cat.:
    E1470h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Laminin subunit gamma-2
    Cat.:
    E1470m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Laminin subunit gamma-2
    Cat.:
    U1470m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Laminin subunit gamma-2
    Cat.:
    U1470h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Laminin subunit gamma-2
    Cat.:
    P1470Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Laminin subunit gamma-2
    Cat.:
    P1470Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Laminin subunit gamma-2
    Monoclonal Antibody for Human Laminin subunit gamma-2
    Protein for Human Laminin subunit gamma-2
    Protein for Human Laminin subunit gamma-2

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "A truncated laminin chain homologous to the B2 chain: structure, spatial expression, and chromosomal assignment."
      Kallunki P. , Sainio K. , Eddy R. , Byers M. , Kallunki T. , Sariola H. , Beck K. , Hirvonen H. , Shows T.B. , Tryggvason K.
      J. Cell Biol.119:679-693(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];ALTERNATIVE SPLICING
      tissue: Fibrosarcoma.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 1090-1114
      tissue: Epidermis.
      tissue: Keratinocyte.
    3. 3.
      "Structure of the human laminin gamma 2 chain gene (LAMC2): alternative splicing with different tissue distribution of two transcripts."
      Airenne T. , Haakana H. , Sainio K. , Kallunki T. , Kallunki P. , Sariola H. , Tryggvason K.
      Genomics32:54-64(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];ALTERNATIVE SPLICING
      tissue: Placenta.
    4. 4.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM SHORT)
      tissue: Cerebellum.
    7. 7.
      "A large cell-adhesive scatter factor secreted by human gastric carcinoma cells."
      Miyazaki K. , Kikkawa Y. , Nakamura A. , Yasumitsu H. , Umeda M.
      Proc. Natl. Acad. Sci. U.S.A.90:11767-11771(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 435-449;FUNCTION;HEPARIN-BINDING
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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