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Index > Protein center > LBP(Gene name) > Human
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  • LBP (Gene name),
  • Lipopolysaccharide-binding protein (Protein name ),  LBP_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    LBP;
    Protein name:
    Lipopolysaccharide-binding protein(LBP);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. The LBP/LPS complex seems to interact with the CD14 receptor.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    481
    Sequence:
    50:
    MGALARALPS | ILLALLLTST | PEALGANPGL | VARITDKGLQ | YAAQEGLLAL | 
    100:
    QSELLRITLP | DFTGDLRIPH | VGRGRYEFHS | LNIHSCELLH | SALRPVPGQG | 
    150:
    LSLSISDSSI | RVQGRWKVRK | SFFKLQGSFD | VSVKGISISV | NLLLGSESSG | 
    200:
    RPTVTASSCS | SDIADVEVDM | SGDLGWLLNL | FHNQIESKFQ | KVLESRICEM | 
    250:
    IQKSVSSDLQ | PYLQTLPVTT | EIDSFADIDY | SLVEAPRATA | QMLEVMFKGE | 
    300:
    IFHRNHRSPV | TLLAAVMSLP | EEHNKMVYFA | ISDYVFNTAS | LVYHEEGYLN | 
    350:
    FSITDDMIPP | DSNIRLTTKS | FRPFVPRLAR | LYPNMNLELQ | GSVPSAPLLN | 
    400:
    FSPGNLSVDP | YMEIDAFVLL | PSSSKEPVFR | LSVATNVSAT | LTFNTSKITG | 
    450:
    FLKPGKVKVE | LKESKVGLFN | AELLEALLNY | YILNTFYPKF | NDKLAEGFPL | 
    481:
    PLLKRVQLYD | LGLQIHKDFL | FLGANVQYMR | V
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    MIM:
    String:
    KEGG:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human LBP
    Cat.:
    E1406h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human LBP
    Cat.:
    E1406r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human LBP
    Cat.:
    E1406b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human LBP
    Cat.:
    E1406m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human LBP
    MSDS:
    Please sign in first.
    CLIA Kit for Human LBP
    Cat.:
    U1406m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human LBP
    Cat.:
    U1406b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human LBP
    MSDS:
    Please sign in first.
    CLIA Kit for Human LBP
    Cat.:
    U1406r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human LBP
    Cat.:
    U1406h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human LBP
    Polyclonal Antibody for Human LBP
    Cat.:
    P1406Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human LBP
    Polyclonal Antibody for Human LBP
    Cat.:
    P1406Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human LBP
    Cat.:
    P1406Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human LBP
    Monoclonal Antibody for Human LBP
    Monoclonal Antibody for Human LBP
    Monoclonal Antibody for Human LBP
    Monoclonal Antibody for Human LBP
    Protein for Human LBP
    Protein for Human LBP
    Cat.:
    R1406h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Human LBP
    Protein for Human LBP
    Protein for Human LBP

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    Precision
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT LEU-436
    2. 2.
      "Bactericidal/permeability-increasing protein and lipopolysaccharide (LPS)-binding protein. LPS binding properties and effects on LPS-mediated cell activation."
      Wilde C.G. , Seilhamer J.J. , McGrogan M. , Ashton N. , Snable J.L. , Lane J.C. , Leong S.R. , Thornton M.B. , Miller K.L. , Scott R.W.
      J. Biol. Chem.269:17411-17416(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "The genomic organization of the genes for human lipopolysaccharide binding protein (LBP) and bactericidal permeability increasing protein (BPI) is highly conserved."
      Hubacek J.A. , Buchler C. , Aslanidis C. , Schmitz G.
      Biochem. Biophys. Res. Commun.236:427-430(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT LEU-436
    4. 4.
      "Similar organization of the lipopolysaccharide-binding protein (LBP) and phospholipid transfer protein (PLTP) genes suggests a common gene family of lipid-binding proteins."
      Kirschning C.J. , Au-Young J. , Lamping N. , Reuter D. , Pfeil D. , Seilhamer J.J. , Schumann R.R.
      Genomics46:416-425(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    5. 5.
      "Cloning and sequencing of human lipopolysaccharide-binding protein gene."
      Long J.Y. , Liu J.Q. , Xue Y.N. , Wang H.X.
      Sheng Wu Hua Xue Yu Sheng Wu Wu Li Jin Zhan25:469-471(1998)
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT LEU-436
      tissue: Liver.
    6. 6.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Liver.
    7. 7.
      "The DNA sequence and comparative analysis of human chromosome 20."
      Deloukas P. , Matthews L.H. , Ashurst J.L. , Burton J. , Gilbert J.G.R. , Jones M. , Stavrides G. , Almeida J.P. , Babbage A.K. , Bagguley C.L. , Bailey J. , Barlow K.F. , Bates K.N. , Beard L.M. , Beare D.M. , Beasley O.P. , Bird C.P. , Blakey S.E. , more...
      Nature414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 9.
      "Cloning and characterization of the human LBP upstream sequence."
      Sutton C.L. , Smith R.I.F. , Centola M.B. , Theofan G.
      Submitted (1995-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-41
    10. 10.
      "Structural biology of the LPS recognition."
      Jerala R.
      Int. J. Med. Microbiol.297:353-363(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT
    11. 11.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-394
      tissue: Liver.
    12. 12.
      "The crystal structure of lipopolysaccharide binding protein reveals the location of a frequent mutation that impairs innate immunity."
      Eckert J.K. , Kim Y.J. , Kim J.I. , Guertler K. , Oh D.Y. , Sur S. , Lundvall L. , Hamann L. , van der Ploeg A. , Pickkers P. , Giamarellos-Bourboulis E. , Kubarenko A.V. , Weber A.N. , Kabesch M. , Kumpf O. , An H.J. , Lee J.O. , Schumann R.R.
      Immunity39:647-660(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;3D-STRUCTURE MODELING;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;GLYCOSYLATION;VARIANT LEU-333;CHARACTERIZATION OF VARIANT LEU-333
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