Protein name:
Galectin-3 (Gal-3) ;
Alternative:
Carbohydrate-binding protein 35 (CBP 35) ;35 kDa lectin ;IgE-binding protein ;Galactose-specific lectin 3 ;Lectin L-29 ;Laminin-binding protein ;Mac-2 antigen ;
Organism:
Dog (Canis familiarisCanis lupus familiaris).
General Annotation
Sub Unit:
Probably forms homo- or heterodimers. Forms a complex with the ITGA3, ITGB1 and CSPG4. Interacts with LGALS3BP, LYPD3, CYHR1 and UACA. Interacts with DMBT1.
Function:
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
Subcellular Location:
Cytoplasm
Nucleus
Secreted
Secreted by a non-classical secretory pathway and associates with the cell surface.
Protein Attributes:
50:
MADSFSLNDA | LSGSGNPNPQ | GWPGPWGNQP | AGAGGYPGAS | YPGAYPGQAP |
100:
PGGYPGQAPP | GGYPGQAPPG | GYPGQAPPGG | YPGQAPPGGY | PGQAPPGGYP |
150:
GQAPPGTYPG | PTAPAYPGPT | APGTQPGQPS | GPGAYPPPGQ | PSAPGAYPAA |
200:
GPFGIPAGPL | TVPYDLPLPG | GVKPRMLITI | LGTVRPSANR | LALDFKRGND |
250:
VAFHFNPRFN | EDNKRVIVCN | TKLDNIWGKE | ERQAAFPFES | GKPFKIQVLV |
296:
ESDHFKVAVN | DAHLLQYNHR | MKNLPEISKL | GISGDIDLTS | ASYAMI
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rat
Dog
Rabbit
Polyclonal Antibody for Dog Gal-3
Polyclonal Antibody for Dog Gal-3
Polyclonal Antibody for Dog Gal-3
Polyclonal Antibody for Dog Gal-3
Polyclonal Antibody for Dog Gal-3
Monoclonal Antibody for Dog Gal-3
Monoclonal Antibody for Dog Gal-3
Monoclonal Antibody for Dog Gal-3
Monoclonal Antibody for Dog Gal-3
Monoclonal Antibody for Dog Gal-3
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Primary structure of the soluble lactose binding lectin L-29 from rat and dog and interaction of its non-collagenous proline-, glycine-, tyrosine-rich sequence with bacterial and tissue collagenase."
Herrmann J.
,
Turck C.W.
,
Atchison R.E.
,
Huflejt M.E.
,
Poulter L.
,
Gitt M.A.
,
Burlingame A.L.
,
Barondes S.H.
,
Leffler H.
J. Biol. Chem.268:26704-26711(1993)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 12-296;PARTIAL PROTEIN SEQUENCE
strain :
Cocker spaniel .
tissue :
Kidney .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION AT SER-6 AND SER-12