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Index > Protein center > LGALS3(Gene name) > Dog
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  • LGALS3 (Gene name),
  • Galectin-3 (Protein name ),  LEG3_CANFA from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    LGALS3;
    Protein name:
    Galectin-3(Gal-3);
    Alternative:
    Carbohydrate-binding protein 35(CBP 35);35 kDa lectin;IgE-binding protein;Galactose-specific lectin 3;Lectin L-29;Laminin-binding protein;Mac-2 antigen;
    Organism:
    Dog (Canis familiarisCanis lupus familiaris). 
    General Annotation
    Sub Unit:
    Probably forms homo- or heterodimers. Forms a complex with the ITGA3, ITGB1 and CSPG4. Interacts with LGALS3BP, LYPD3, CYHR1 and UACA. Interacts with DMBT1.
    Function:
    Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
    Subcellular Location:
    Cytoplasm Nucleus Secreted Secreted by a non-classical secretory pathway and associates with the cell surface.
    Protein Attributes:
    Sequence length:
    296
    Sequence:
    50:
    MADSFSLNDA | LSGSGNPNPQ | GWPGPWGNQP | AGAGGYPGAS | YPGAYPGQAP | 
    100:
    PGGYPGQAPP | GGYPGQAPPG | GYPGQAPPGG | YPGQAPPGGY | PGQAPPGGYP | 
    150:
    GQAPPGTYPG | PTAPAYPGPT | APGTQPGQPS | GPGAYPPPGQ | PSAPGAYPAA | 
    200:
    GPFGIPAGPL | TVPYDLPLPG | GVKPRMLITI | LGTVRPSANR | LALDFKRGND | 
    250:
    VAFHFNPRFN | EDNKRVIVCN | TKLDNIWGKE | ERQAAFPFES | GKPFKIQVLV | 
    296:
    ESDHFKVAVN | DAHLLQYNHR | MKNLPEISKL | GISGDIDLTS | ASYAMI
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    String:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Dog Gal-3
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    E0497m
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    ELISA Kit for Dog Gal-3
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    E0497h
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    ELISA Kit for Dog Gal-3
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    E0497r
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    ELISA Kit for Dog Gal-3
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    E0497d
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    ELISA Kit for Dog Gal-3
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    CLIA Kit for Dog Gal-3
    Cat.:
    U0497d
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    96T
    CLIA Kit for Dog Gal-3
    Cat.:
    U0497r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Dog Gal-3
    MSDS:
    Please sign in first.
    CLIA Kit for Dog Gal-3
    Cat.:
    U0497h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Dog Gal-3
    Cat.:
    U0497m
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
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    Polyclonal Antibody for Dog Gal-3
    Polyclonal Antibody for Dog Gal-3
    Cat.:
    P0497Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog Gal-3
    Cat.:
    P0497Rb-h
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    Polyclonal Antibody for Dog Gal-3
    Cat.:
    P0497Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog Gal-3
    Monoclonal Antibody for Dog Gal-3
    Monoclonal Antibody for Dog Gal-3
    Monoclonal Antibody for Dog Gal-3
    Monoclonal Antibody for Dog Gal-3
    Monoclonal Antibody for Dog Gal-3
    Protein for Dog Gal-3
    Protein for Dog Gal-3
    Protein for Dog Gal-3
    Protein for Dog Gal-3
    Protein for Dog Gal-3

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    References
    1. 1.
      "Primary structure of the soluble lactose binding lectin L-29 from rat and dog and interaction of its non-collagenous proline-, glycine-, tyrosine-rich sequence with bacterial and tissue collagenase."
      Herrmann J. , Turck C.W. , Atchison R.E. , Huflejt M.E. , Poulter L. , Gitt M.A. , Burlingame A.L. , Barondes S.H. , Leffler H.
      J. Biol. Chem.268:26704-26711(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 12-296;PARTIAL PROTEIN SEQUENCE
      strain: Cocker spaniel.
      tissue: Kidney.
    2. 2.
      "L-29, a soluble lactose-binding lectin, is phosphorylated on serine 6 and serine 12 in vivo and by casein kinase I."
      Huflejt M.E. , Turck C.W. , Lindstedt R. , Barondes S.H. , Leffler H.
      J. Biol. Chem.268:26712-26718(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-6 AND SER-12
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