Protein name:
Galectin-3 (Gal-3) ;
Alternative:
Carbohydrate-binding protein 35 (CBP 35) ;35 kDa lectin ;Galactoside-binding protein (GALBP) ;Galactose-specific lectin 3 ;L-31 ;IgE-binding protein ;Lectin L-29 ;Laminin-binding protein ;Mac-2 antigen ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Probably forms homo- or heterodimers. Interacts with DMBT1 (By similarity). Forms a complex with the ITGA3, ITGB1 and CSPG4. Interacts with LGALS3BP, LYPD3, CYHR1 and UACA.
Function:
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
Subcellular Location:
Cytoplasm
Nucleus
Secreted
Secreted by a non-classical secretory pathway and associates with the cell surface.
Protein Attributes:
50:
MADNFSLHDA | LSGSGNPNPQ | GWPGAWGNQP | AGAGGYPGAS | YPGAYPGQAP |
100:
PGAYPGQAPP | GAYPGAPGAY | PGAPAPGVYP | GPPSGPGAYP | SSGQPSATGA |
150:
YPATGPYGAP | AGPLIVPYNL | PLPGGVVPRM | LITILGTVKP | NANRIALDFQ |
200:
RGNDVAFHFN | PRFNENNRRV | IVCNTKLDNN | WGREERQSVF | PFESGKPFKI |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rat
Dog
Rabbit
ELISA Kit for Human Gal-3
ELISA Kit for Human Gal-3
ELISA Kit for Human Gal-3
ELISA Kit for Human Gal-3
ELISA Kit for Human Gal-3
Polyclonal Antibody for Human Gal-3
Polyclonal Antibody for Human Gal-3
Polyclonal Antibody for Human Gal-3
Polyclonal Antibody for Human Gal-3
Polyclonal Antibody for Human Gal-3
Monoclonal Antibody for Human Gal-3
Monoclonal Antibody for Human Gal-3
Monoclonal Antibody for Human Gal-3
Monoclonal Antibody for Human Gal-3
Monoclonal Antibody for Human Gal-3
R&D Technical Data
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Precision
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Recovery
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Linearity
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Citations
[1].
X Zhou, J Jing, W Mao, et al.
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[
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[
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Thalamus .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 114-250