LGALS9 ELISA Kit for Human(Homo sapiens) | EIAab.comLGALS9 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > LGALS9(Gene name) > Human

LGALS9 (Gene name),

Galectin-9 (Protein name ), LEG9_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

LGALS9;

Protein name:

Galectin-9(Gal-9);

Alternative:

Tumor antigen HOM-HD-21;Ecalectin;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Monomer.

Function:

Binds galactosides. Has high affinity for the Forssman pentasaccharide. May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. Inhibits cell proliferation. It is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death. Isoform Short acts as an eosinophil chemoattractant.

Subcellular Location:

Cytoplasm Secreted May also be secreted by a non-classical secretory pathway.

Protein Attributes:

Sequence length:

355

Sequence:

50:

100:

150:

200:

250:

300:

350:

355:

THVQT

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

O00182

Pfam:

PF00337

UniGene:

Hs.81337

MIM:

601879

SMR:

O00182

KEGG:

hsa:3965

STRING:

9606.ENSP00000378856

Uniprot:

O00182

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ELISA Kit for Human Gal-9

Cat.:

E0445h

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96T

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ELISA Kit for Human Gal-9

Cat.:

E0445b

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96T

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ELISA Kit for Human Gal-9

Cat.:

E0445m

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96T

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ELISA Kit for Human Gal-9

Cat.:

E0445r

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96T

CLIA Kit for Human Gal-9

Cat.:

U0445m

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96T

CLIA Kit for Human Gal-9

Cat.:

U0445b

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96T

CLIA Kit for Human Gal-9

Cat.:

U0445r

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96T

CLIA Kit for Human Gal-9

Cat.:

U0445h

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96T

Polyclonal Antibody for Human Gal-9

Cat.:

P0445Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Gal-9

Cat.:

P0445Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human Gal-9

Cat.:

P0445Rb-r

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40ug/0.2ml

Polyclonal Antibody for Human Gal-9

Monoclonal Antibody for Human Gal-9

Protein for Human Gal-9

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Molecular definition of a novel human galectin which is immunogenic in patients with Hodgkin's disease."
Tuereci O. , Schmitt H. , Fadle N. , Pfreundschuh M. , Sahin U.
J. Biol. Chem.272:6416-6422(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM SHORT)
tissue: Spleen.
2.

"Human galectin-9 isoform full-length cDNA from gastric adenocarcinoma."
Kato S.
Submitted (1997-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG)
tissue: Gastric carcinoma.
3.

"Human ecalectin, a variant of human galectin-9, is a novel eosinophil chemoattractant produced by T lymphocytes."
Matsumoto R. , Matsumoto H. , Seki M. , Hata M. , Asano Y. , Kanegasaki S. , Stevens R.L. , Hirashima M.
J. Biol. Chem.273:16976-16984(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM SHORT);VARIANT SER-5
4.

"Cloning and expression of human urate transporter mRNA."
Nakajima H. , Shichiri M. , Hamaguchi T.
Submitted (1997-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS LONG AND SHORT)
tissue: Kidney.
tissue: Stomach.
5.

"Homo sapiens galectin-9 (LGALS9) / ecalectin gene, exon 2 through 11."
Akiyama S.
Submitted (2000-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
6.

"Genomic organization of the human galectin-9 gene."
Graessler J. , Spitzenberger F. , Schroeder H.E.
Submitted (2000-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
7.

Suzuki Y. , Sugano S. , Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S.
Submitted (2005-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM SHORT);VARIANT SER-5
tissue: Gastric mucosa.
8.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM SHORT)
tissue: Colon.
10.

"The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity."
Zhu C. , Anderson A.C. , Schubart A. , Xiong H. , Imitola J. , Khoury S.J. , Zheng X.X. , Strom T.B. , Kuchroo V.K.
Nat. Immunol.6:1245-1252(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS LIGAND FOR HAVCR2/TIM3
11.

"Structural analysis of the human galectin-9 N-terminal carbohydrate recognition domain reveals unexpected properties that differ from the mouse orthologue."
Nagae M. , Nishi N. , Nakamura-Tsuruta S. , Hirabayashi J. , Wakatsuki S. , Kato R.
J. Mol. Biol.375:119-135(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS) OF 1-148 IN COMPLEXES WITH LACTOSE AND COMPLEX BETA-GALACTOSIDE;SUBUNIT;CARBOHYDRATE SPECIFICITY;FUNCTION
12.

"Crystal structure of N-terminal domain of human galectin-9 containing L-acetyllactosamine."
RIKEN structural genomics initiative (RSGI)
Submitted (2008-04) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.17 ANGSTROMS) OF 1-150 IN COMPLEX WITH L-ACETYLLACTOSAMINE
13.

"Structural analysis of the recognition mechanism of poly-N-acetyllactosamine by the human galectin-9 N-terminal carbohydrate recognition domain."
Nagae M. , Nishi N. , Murata T. , Usui T. , Nakamura T. , Wakatsuki S. , Kato R.
Glycobiology19:112-117(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.3 ANGSTROMS) OF 1-148 IN COMPLEXES WITH N-ACETYLLACTOSAMINE OLIGOMERS;FUNCTION
14.

"X-ray structures of human galectin-9 C-terminal domain in complexes with a biantennary oligosaccharide and sialyllactose."
Yoshida H. , Teraoka M. , Nishi N. , Nakakita S. , Nakamura T. , Hirashima M. , Kamitori S.
J. Biol. Chem.285:36969-36976(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.5 ANGSTROMS) OF 186-323 IN COMPLEXES WITH OLIGOSACCHARIDES

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