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Index > Protein center > Alox12(Gene name) > Mouse
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  • Alox12 (Gene name),
  • Arachidonate 12-lipoxygenase, 12S-type (Protein name ),  LOX12_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Alox12(Alox12p);
    Protein name:
    Arachidonate 12-lipoxygenase, 12S-type(12S-LOX;12S-lipoxygenase);
    Alternative:
    Platelet-type lipoxygenase 12(P-12LO);3.3.2.-;Platelet-type lipoxygenase 12);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Oxygenase and 14,15-leukotriene A4 synthase activity.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    663
    Sequence:
    50:
    MGRYRVRVVT | GAWLFSGSLN | LVRLWLVGEH | REAKLELQLR | PARGKEEEFD | 
    100:
    FDVPEDLGPL | QFVKLHKQHT | VVDDAWFCNL | ITVQGPGTSA | EAVFPCYRWV | 
    150:
    QGEGILSLPE | GTARLAGDNA | LDVFQKYREK | ELKERQQTYC | WATWKEGLPQ | 
    200:
    TIAADCKDDL | PPNMRFHEEK | RLDFEWTLKA | GVLEMGLKRV | YTLLRSWNHL | 
    250:
    EDFDQIFWGQ | KSALAEKVHQ | CWQEDELFGY | QFLNGANPML | LRRSTSLPSR | 
    300:
    LVLPSGMEEL | QAQLEKELKN | GSLFEADFIL | LDGIPANVIR | GEPQYLAAPL | 
    350:
    VMLRMDPGGK | LLPMAIQIQP | PNPSSPAPTL | FLPSDPPLAW | LLAKIWVRNS | 
    400:
    DFQLQELQFH | LLNTHLVAEV | IAVATMRCLP | GLHPIFKLLV | PHIRYTMEIN | 
    450:
    TRSRTQLISD | GGIFDQVVST | GGGGHVQLLT | RAVAQLTYHS | LCPPDDLANR | 
    500:
    GLLRIPSALY | ARDALQLWEV | TARYVKGMVH | LFYQSDDIVR | GDPELQAWCR | 
    550:
    EITEVGLCHA | QDRGFPVSFQ | SRAQLCHFLT | MCVFTCTAQH | AAINQGQLDW | 
    600:
    YGWVPNAPCT | MRMPPPTSKD | DVTMETVMGS | LPDVQKACLQ | MTITWHLGRL | 
    650:
    QPDMVPLGHH | TEKYFSDPRT | KAVLSQFQAD | LDNLEKEITA | RNEQLDLPYE | 
    663:
    YLKPSRIENS | ITI
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    UniGene:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse 12S-LOX
    Cat.:
    E1965h
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse 12S-LOX
    Cat.:
    E1965b
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse 12S-LOX
    Cat.:
    E1965m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse 12S-LOX
    Cat.:
    E1965p
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse 12S-LOX
    Cat.:
    E1965r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse 12S-LOX
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse 12S-LOX
    Cat.:
    U1965r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse 12S-LOX
    Cat.:
    U1965h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse 12S-LOX
    Cat.:
    U1965m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse 12S-LOX
    Cat.:
    U1965b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse 12S-LOX
    Cat.:
    U1965p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse 12S-LOX
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Mouse 12S-LOX
    Polyclonal Antibody for Mouse 12S-LOX
    Polyclonal Antibody for Mouse 12S-LOX
    Cat.:
    P1965Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse 12S-LOX
    Cat.:
    P1965Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse 12S-LOX
    Cat.:
    P1965Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse 12S-LOX
    Monoclonal Antibody for Mouse 12S-LOX
    Monoclonal Antibody for Mouse 12S-LOX
    Monoclonal Antibody for Mouse 12S-LOX
    Monoclonal Antibody for Mouse 12S-LOX
    Monoclonal Antibody for Mouse 12S-LOX
    Monoclonal Antibody for Mouse 12S-LOX
    Protein for Mouse 12S-LOX
    Protein for Mouse 12S-LOX
    Protein for Mouse 12S-LOX
    Protein for Mouse 12S-LOX
    Protein for Mouse 12S-LOX
    Protein for Mouse 12S-LOX

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    References
    1. 1.
      "cDNA cloning, expression, mutagenesis of C-terminal isoleucine, genomic structure, and chromosomal localizations of murine 12-lipoxygenases."
      Chen X.-S. , Kurre U. , Jenkins N.A. , Copeland N.G. , Funk C.D.
      J. Biol. Chem.269:13979-13987(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];CATALYTIC ACTIVITY;MUTAGENESIS OF ILE-663;TISSUE SPECIFICITY
      strain: C57BL/6.
      strain: ICR.
      tissue: Spleen.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Ovary.
      tissue: Vagina.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    5. 5.
      "12-lipoxygenase in Lewis lung carcinoma cells: molecular identity, intracellular distribution of activity and protein, and Ca(2+)-dependent translocation from cytosol to membranes."
      Hagmann W. , Gao X. , Zacharek A. , Wojciechowski L.A. , Honn K.V.
      Prostaglandins49:49-62(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 126-218
      tissue: Lung.
    6. 6.
      "Immunocytochemical localization of platelet-type arachidonate 12-lipoxygenase in mouse blood cells."
      Nakamura M. , Ueda N. , Kishimoto K. , Yoshimoto T. , Yamamoto S. , Ishimura K.
      J. Histochem. Cytochem.43:237-244(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    7. 7.
      "Increased platelet sensitivity to ADP in mice lacking platelet-type 12-lipoxygenase."
      Johnson E.N. , Brass L.F. , Funk C.D.
      Proc. Natl. Acad. Sci. U.S.A.95:3100-3105(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN PLATELET ACTIVATION;DISRUPTION PHENOTYPE;TISSUE SPECIFICITY
    8. 8.
      "Basal transepidermal water loss is increased in platelet-type 12-lipoxygenase deficient mice."
      Johnson E.N. , Nanney L.B. , Virmani J. , Lawson J.A. , Funk C.D.
      J. Invest. Dermatol.112:861-865(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;TISSUE SPECIFICITY
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