ALOX15 ELISA Kit for Human(Homo sapiens) | EIAab.comALOX15 ELISA Kit for Human(Homo sapiens)

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ALOX15 (Gene name),

Arachidonate 15-lipoxygenase (Protein name ), LOX15_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ALOX15(LOG15);

Protein name:

Arachidonate 15-lipoxygenase(15-LOX);

Alternative:

1.13.11.31;Arachidonate 12-lipoxygenase, leukocyte-type(12-LOX);Arachidonate omega-6 lipoxygenase;Arachidonate omega-6 lipoxygenase;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid. Also acts on C-12 of arachidonate as well as on linoleic acid.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

662

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

662:

LRPSVVENSV | AI

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:246

Pfam:

PF00305

String:

P16050

STRING:

9606.ENSP00000293761

UniGene:

Hs.73809

SMR:

P16050

MIM:

152392

Uniprot:

P16050

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ELISA Kit for Human 15-LOX

Cat.:

E0891h

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Manual:

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96T

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ELISA Kit for Human 15-LOX

Cat.:

E0891r

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96T

ELISA Kit for Human 15-LOX

Cat.:

E0891p

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96T

ELISA Kit for Human 15-LOX

Cat.:

E0891m

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Packing:

96T

ELISA Kit for Human 15-LOX

MSDS:

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ELISA Kit for Human 15-LOX

Cat.:

E0891b

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96T

CLIA Kit for Human 15-LOX

Cat.:

U0891r

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96T

CLIA Kit for Human 15-LOX

Cat.:

U0891p

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MSDS:

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Packing:

96T

CLIA Kit for Human 15-LOX

Cat.:

U0891h

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MSDS:

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Packing:

96T

CLIA Kit for Human 15-LOX

Cat.:

U0891b

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MSDS:

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Packing:

96T

CLIA Kit for Human 15-LOX

MSDS:

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CLIA Kit for Human 15-LOX

Cat.:

U0891m

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96T

Polyclonal Antibody for Human 15-LOX

Cat.:

P0891Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human 15-LOX

Cat.:

P0891Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human 15-LOX

Cat.:

P0891Rb-r

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human 15-LOX

Protein for Human 15-LOX

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Molecular cloning and primary structure of human 15-lipoxygenase."
Sigal E. , Craik C.S. , Highland E. , Grunberger D. , Costello L.L. , Dixon R.A.F. , Nadel J.A.
Biochem. Biophys. Res. Commun.157:457-464(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);SUBCELLULAR LOCATION
2.

"Characterization and sequence of an additional 15-lipoxygenase transcript and of the human gene."
Kritzik M.R. , Ziober A.F. , Dicharry S. , Conrad D.J. , Sigal E.
Biochim. Biophys. Acta1352:267-281(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue: Tongue.
4.

SeattleSNPs variation discovery resource
Submitted (2003-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS HIS-90; LYS-103 AND GLN-205
5.

"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Zody M.C. , Garber M. , Adams D.J. , Sharpe T. , Harrow J. , Lupski J.R. , Nicholson C. , Searle S.M. , Wilming L. , Young S.K. , Abouelleil A. , Allen N.R. , Bi W. , Bloom T. , Borowsky M.L. , Bugalter B.E. , Butler J. , Chang J.L. , more...
Nature440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT PRO-461
tissue: Brain.
tissue: Lung.
7.

"Human 15-lipoxygenase gene promoter: analysis and identification of DNA binding sites for IL-13-induced regulatory factors in monocytes."
Kelavkar U. , Wang S. , Montero A. , Murtagh J. , Shah K. , Badr K.
Mol. Biol. Rep.25:173-182(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-46
8.

"Arachidonate 15-lipoxygenase (omega-6 lipoxygenase) from human leukocytes. Purification and structural homology to other mammalian lipoxygenases."
Sigal E. , Grunberger D. , Craik C.S. , Caughey G.H. , Nadel J.A.
J. Biol. Chem.263:5328-5332(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-16
9.

"Purification of two forms of arachidonate 15-lipoxygenase from human leukocytes."
Izumi T. , Raadmark O. , Joernvall H. , Samuelsson B.
Eur. J. Biochem.202:1231-1238(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-31; 38-45; 157-168 AND 626-631
tissue: Eosinophil.
tissue: Leukocyte.
10.

"A primary determinant for lipoxygenase positional specificity."
Sloane D.L. , Leung R. , Craik C.S. , Sigal E.
Nature354:149-152(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY;MUTAGENESIS OF MET-418
11.

"Membrane translocation of 15-lipoxygenase in hematopoietic cells is calcium-dependent and activates the oxygenase activity of the enzyme."
Brinckmann R. , Schnurr K. , Heydeck D. , Rosenbach T. , Kolde G. , Kuehn H.
Blood91:64-74(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY
12.

"Evaluation of the activity and localization of 15-lipoxygenase-1 after introduction into human colorectal carcinoma Caco-2 cells."
Hsi L.C. , Kamitani H. , Cornicelli J.A. , Eling T.E.
Prostaglandins Leukot. Essent. Fatty Acids64:217-225(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
13.

"Interaction of human 15-lipoxygenase-1 with phosphatidylinositol bisphosphates results in increased enzyme activity."
Andersson E. , Schain F. , Svedling M. , Claesson H.E. , Forsell P.K.
Biochim. Biophys. Acta1761:1498-1505(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: LIPID-BINDING;SUBCELLULAR LOCATION;CATALYTIC ACTIVITY;FUNCTION;ENZYME REGULATION
14.

"Reciprocal regulation of 12- and 15-lipoxygenases by UV-irradiation in human keratinocytes."
Yoo H. , Jeon B. , Jeon M.S. , Lee H. , Kim T.Y.
FEBS Lett.582:3249-3253(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION BY UV
15.

"15(S)-Lipoxygenase-1 associates with neutral lipid droplets in macrophage foam cells: evidence of lipid droplet metabolism."
Weibel G.L. , Joshi M.R. , Wei C. , Bates S.R. , Blair I.A. , Rothblat G.H.
J. Lipid Res.50:2371-2376(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
16.

"15-Lipoxygenase 1 interacts with phosphatidylethanolamine-binding protein to regulate MAPK signaling in human airway epithelial cells."
Zhao J. , O'Donnell V.B. , Balzar S. , St Croix C.M. , Trudeau J.B. , Wenzel S.E.
Proc. Natl. Acad. Sci. U.S.A.108:14246-14251(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN IL13 SIGNALING;INTERACTION WITH PEBP1;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
17.

"A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease."
Assimes T.L. , Knowles J.W. , Priest J.R. , Basu A. , Borchert A. , Volcik K.A. , Grove M.L. , Tabor H.K. , Southwick A. , Tabibiazar R. , Sidney S. , Boerwinkle E. , Go A.S. , Iribarren C. , Hlatky M.A. , Fortmann S.P. , Myers R.M. , Kuhn H. , more...
Atherosclerosis198:136-144(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MET-560;CHARACTERIZATION OF VARIANT MET-560;INVOLVEMENT IN CORONARY ARTERY DISEASE

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