Protein name:
Arachidonate 5-lipoxygenase (5-LO;5-lipoxygenase) ;
Alternative:
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Interacts with ALOX5AP and LTC4S.
Function:
Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes.
Subcellular Location:
Cytoplasm
Nucleus matrix
Nucleus membrane
Peripheral membrane protein
Shuttles between cytoplasm and nucleus. Found exclusively in the nucleus, when phosphorylated on Ser-271. Calcium binding promotes translocation from the cytosol and the nuclear matrix to the nuclear envelope and membrane association.
Protein Attributes:
50:
MPSYTVTVAT | GSQWFAGTDD | YIYLSLIGSA | GCSEKHLLDK | AFYNDFERGG |
100:
RDSYDVTVDE | ELGEIYLVKI | EKRKYRLHDD | WYLKYITLKT | PHDYIEFPCY |
150:
RWITGEGEIV | LRDGCAKLAR | DDQIHILKQH | RRKELETRQK | QYRWMEWNPG |
200:
FPLSIDAKCH | KDLPRDIQFD | SEKGVDFVLN | YSKAMENLFI | NRFMHMFQSS |
250:
WHDFADFEKI | FVKISNTISE | RVKNHWQEDL | MFGYQFLNGC | NPVLIKRCTE |
300:
LPKKLPVTTE | MVECSLERQL | SLEQEVQEGN | IFIVDYELLD | GIDANKTDPC |
350:
THQFLAAPIC | LLYKNLANKI | VPIAIQLNQT | PGEKNPIFLP | TDSKYDWLLA |
400:
KIWVRSSDFH | IHQTITHLLR | THLVSEVFGI | AMYRQLPAVH | PLFKLLVAHV |
450:
RFTIAINTKA | REQLNCEYGL | FDKANATGGG | GHVQMVQRAV | QDLTYSSLCF |
500:
PEAIKARGMD | NTEDIPYYFY | RDDGLLVWEA | IQSFTTEVVS | IYYEDDQVVE |
550:
EDQELQDFVK | DVYVYGMRGR | KASGFPKSIK | SREKLSEYLT | VVIFTASAQH |
600:
AAVNFGQYDW | CSWIPNAPPT | MRAPPPTAKG | VVTIEQIVDT | LPDRGRSCWH |
650:
LGAVWALSQF | QENELFLGMY | PEEHFIEKPV | KEAMIRFRKN | LEAIVSVIAE |
673:
RNKNKKLPYY | YLSPDRIPNS | VAI
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Polyclonal Antibody for Rat 5-LO
Polyclonal Antibody for Rat 5-LO
Polyclonal Antibody for Rat 5-LO
Monoclonal Antibody for Rat 5-LO
Monoclonal Antibody for Rat 5-LO
Monoclonal Antibody for Rat 5-LO
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SEQUENCE REVISION TO 667-670