ALOXE3 ELISA Kit for Human(Homo sapiens) | EIAab.comALOXE3 ELISA Kit for Human(Homo sapiens)

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ALOXE3 (Gene name),

Epidermis-type lipoxygenase 3 (Protein name ), LOXE3_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ALOXE3;

Protein name:

Epidermis-type lipoxygenase 3(e-LOX-3);

Alternative:

1.13.11.-;Epidermis-type lipoxygenase 3(Epidermal LOX-3);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Introduces molecular oxygen into polyunsaturated fatty acids. Exact substrate is not known.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

711

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

711:

DPPLIENSVS | I

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q9BYJ1

Pfam:

PF00305

UniGene:

Hs.232770

MIM:

242100

STRING:

9606.ENSP00000314879

KEGG:

hsa:59344

String:

Q9BYJ1

MIM:

606545

Uniprot:

Q9BYJ1

FOR

ELISA Kit for Human e-LOX-3

CLIA Kit for Human e-LOX-3

Polyclonal Antibody for Human e-LOX-3

Monoclonal Antibody for Human e-LOX-3

Protein for Human e-LOX-3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"A gene cluster encoding human epidermis-type lipoxygenases at chromosome 17p13.1: cloning, physical mapping, and expression."
Krieg P. , Marks F. , Fuerstenberger G.
Genomics73:323-330(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1)
2.

"The lipoxygenase gene ALOXE3 implicated in skin differentiation encodes a hydroperoxide isomerase."
Yu Z. , Schneider C. , Boeglin W.E. , Marnett L.J. , Brash A.R.
Proc. Natl. Acad. Sci. U.S.A.100:9162-9167(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION IN HEPOXILIN A3 SYNTHESIS;CATALYTIC ACTIVITY;PATHWAY;REACTION MECHANISM;KINETIC PARAMETERS
3.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue: Thalamus.
4.

Mural R.J. , Istrail S. , Sutton G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
6.

"Human and mouse eLOX3 have distinct substrate specificities: implications for their linkage with lipoxygenases in skin."
Yu Z. , Schneider C. , Boeglin W.E. , Brash A.R.
Arch. Biochem. Biophys.455:188-196(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS A HYDROPEROXIDE ISOMERASE;CATALYTIC ACTIVITY;KINETIC PARAMETERS;PATHWAY
7.

"Dioxygenase activity of epidermal lipoxygenase-3 unveiled: typical and atypical features of its catalytic activity with natural and synthetic polyunsaturated fatty acids."
Zheng Y. , Brash A.R.
J. Biol. Chem.285:39866-39875(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS A DIOXYGENASE;CATALYTIC ACTIVITY;BIOPHYSICOCHEMICAL PROPERTIES;MUTAGENESIS OF ALA-451
8.

"On the role of molecular oxygen in lipoxygenase activation: comparison and contrast of epidermal lipoxygenase-3 with soybean lipoxygenase-1."
Zheng Y. , Brash A.R.
J. Biol. Chem.285:39876-39887(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS A DIOXYGENASE;CATALYTIC ACTIVITY;MUTAGENESIS OF ALA-451
9.

"Lipoxygenases mediate the effect of essential fatty acid in skin barrier formation: a proposed role in releasing omega-hydroxyceramide for construction of the corneocyte lipid envelope."
Zheng Y. , Yin H. , Boeglin W.E. , Elias P.M. , Crumrine D. , Beier D.R. , Brash A.R.
J. Biol. Chem.286:24046-24056(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN CERAMIDE METABOLISM;CATALYTIC ACTIVITY
10.

"Lipoxygenase-3 (ALOXE3) and 12(R)-lipoxygenase (ALOX12B) are mutated in non-bullous congenital ichthyosiform erythroderma (NCIE) linked to chromosome 17p13.1."
Jobard F. , Lefevre C. , Karaduman A. , Blanchet-Bardon C. , Emre S. , Weissenbach J. , Ozguc M. , Lathrop M. , Prud'homme J.-F. , Fischer J.
Hum. Mol. Genet.11:107-113(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ARCI3 SER-396 AND PHE-500
11.

"Mutations associated with a congenital form of ichthyosis (NCIE) inactivate the epidermal lipoxygenases 12R-LOX and eLOX3."
Yu Z. , Schneider C. , Boeglin W.E. , Brash A.R.
Biochim. Biophys. Acta1686:238-247(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF VARIANTS ARCI3 SER-396 AND PHE-500
12.

"Mutation spectrum and functional analysis of epidermis-type lipoxygenases in patients with autosomal recessive congenital ichthyosis."
Eckl K.M. , Krieg P. , Kuester W. , Traupe H. , Andre F. , Wittstruck N. , Fuerstenberger G. , Hennies H.C.
Hum. Mutat.26:351-361(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ARCI3 MET-237; VAL-281 AND LEU-630;CHARACTERIZATION OF VARIANTS ARCI3 MET-237; VAL-281 AND LEU-630
13.

"Molecular analysis of 250 patients with autosomal recessive congenital ichthyosis: evidence for mutation hotspots in ALOXE3 and allelic heterogeneity in ALOX12B."
Eckl K.M. , de Juanes S. , Kurtenbach J. , Naetebus M. , Lugassy J. , Oji V. , Traupe H. , Preil M.L. , Martinez F. , Smolle J. , Harel A. , Krieg P. , Sprecher E. , Hennies H.C.
J. Invest. Dermatol.129:1421-1428(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ARCI3 MET-237; 344-GLN--ALA-347 DELINS PRO AND LEU-630;CHARACTERIZATION OF VARIANT 344-GLN--ALA-347 DELINS PRO
14.

"Genotypic and clinical spectrum of self-improving collodion ichthyosis: ALOX12B, ALOXE3, and TGM1 mutations in Scandinavian patients."
Vahlquist A. , Bygum A. , Gaanemo A. , Virtanen M. , Hellstroem-Pigg M. , Strauss G. , Brandrup F. , Fischer J.
J. Invest. Dermatol.130:438-443(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ARCI3 PRO-427 AND LEU-630

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