LOXL2 ELISA Kit for Human(Homo sapiens) | EIAab.comLOXL2 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > LOXL2(Gene name) > Human

LOXL2 (Gene name),

Lysyl oxidase homolog 2 (Protein name ), LOXL2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

LOXL2;

Protein name:

Lysyl oxidase homolog 2;

Alternative:

Lysyl oxidase-related protein 2;Lysyl oxidase-like protein 2;Lysyl oxidase-related protein WS9-14;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

N/A

Subcellular Location:

Secreted extracellular space

Protein Attributes:

Sequence length:

774

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

774:

SFSEETEKKF | EHFSGLLNNQ | LSPQ

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

MIM:

606663

String:

Q9Y4K0

SMR:

Q9Y4K0

Pfam:

PF01186

STRING:

9606.ENSP00000373783

KEGG:

hsa:4017

UniGene:

Hs.626637

Uniprot:

Q9Y4K0

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ELISA Kit for Human Lysyl oxidase homolog 2

Cat.:

E14939h

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Human Lysyl oxidase homolog 2

MSDS:

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ELISA Kit for Human Lysyl oxidase homolog 2

MSDS:

Please sign in first.

ELISA Kit for Human Lysyl oxidase homolog 2

Cat.:

E14939r

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Manual:

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Packing:

96T

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ELISA Kit for Human Lysyl oxidase homolog 2

Cat.:

E14939m

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human Lysyl oxidase homolog 2

Cat.:

U14939h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Lysyl oxidase homolog 2

MSDS:

Please sign in first.

CLIA Kit for Human Lysyl oxidase homolog 2

MSDS:

Please sign in first.

CLIA Kit for Human Lysyl oxidase homolog 2

MSDS:

Please sign in first.

CLIA Kit for Human Lysyl oxidase homolog 2

Cat.:

U14939m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Human Lysyl oxidase homolog 2

Monoclonal Antibody for Human Lysyl oxidase homolog 2

Protein for Human Lysyl oxidase homolog 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Regulation of a novel gene encoding a lysyl oxidase-related protein in cellular adhesion and senescence."
Saito H. , Papaconstantinou J. , Sato H. , Goldstein S.
J. Biol. Chem.272:8157-8160(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
3.

Suzuki Y. , Sugano S. , Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S.
Submitted (2005-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT LEU-570
tissue: Adipose tissue.
4.

"DNA sequence and analysis of human chromosome 8."
Nusbaum C. , Mikkelsen T.S. , Zody M.C. , Asakawa S. , Taudien S. , Garber M. , Kodira C.D. , Schueler M.G. , Shimizu A. , Whittaker C.A. , Chang J.L. , Cuomo C.A. , Dewar K. , FitzGerald M.G. , Yang X. , Allen N.R. , Anderson S. , Asakawa T. , more...
Nature439:331-335(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT LEU-570
tissue: Kidney.
6.

"The LOXL2 gene encodes a new lysyl oxidase-like protein and is expressed at high levels in reproductive tissues."
Jourdan-Le Saux C. , Tronecker H. , Bogic L. , Bryant-Greenwood G.D. , Boyd C.D. , Csiszar K.
J. Biol. Chem.274:12939-12944(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 202-774
tissue: Placenta.
tissue: Spleen.
7.

"A molecular role for lysyl oxidase-like 2 enzyme in snail regulation and tumor progression."
Peinado H. , Del Carmen Iglesias-de la Cruz M. , Olmeda D. , Csiszar K. , Fong K.S. , Vega S. , Nieto M.A. , Cano A. , Portillo F.
EMBO J.24:3446-3458(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH SNAI1
8.

"The lysyl oxidases LOX and LOXL2 are necessary and sufficient to repress E-cadherin in hypoxia: insights into cellular transformation processes mediated by HIF-1."
Schietke R. , Warnecke C. , Wacker I. , Schodel J. , Mole D.R. , Campean V. , Amann K. , Goppelt-Struebe M. , Behrens J. , Eckardt K.U. , Wiesener M.S.
J. Biol. Chem.285:6658-6669(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION
9.

"Modulation of lysyl oxidase-like 2 enzymatic activity by an allosteric antibody inhibitor."
Rodriguez H.M. , Vaysberg M. , Mikels A. , McCauley S. , Velayo A.C. , Garcia C. , Smith V.
J. Biol. Chem.285:20964-20974(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY;BIOPHYSICOCHEMICAL PROPERTIES;ENZYME REGULATION
10.

"Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment."
Barry-Hamilton V. , Spangler R. , Marshall D. , McCauley S. , Rodriguez H.M. , Oyasu M. , Mikels A. , Vaysberg M. , Ghermazien H. , Wai C. , Garcia C.A. , Velayo A.C. , Jorgensen B. , Biermann D. , Tsai D. , Green J. , Zaffryar-Eilot S. , Holzer A. , more...
Nat. Med.16:1009-1017(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION
11.

"Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane."
Bignon M. , Pichol-Thievend C. , Hardouin J. , Malbouyres M. , Brechot N. , Nasciutti L. , Barret A. , Teillon J. , Guillon E. , Etienne E. , Caron M. , Joubert-Caron R. , Monnot C. , Ruggiero F. , Muller L. , Germain S.
Blood118:3979-3989(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
12.

"LOXL2-mediated matrix remodeling in metastasis and mammary gland involution."
Barker H.E. , Chang J. , Cox T.R. , Lang G. , Bird D. , Nicolau M. , Evans H.R. , Gartland A. , Erler J.T.
Cancer Res.71:1561-1572(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ROLE IN TUMOR PROGRESSION
13.

"Lysyl oxidase-like 2 (LOXL2), a new regulator of cell polarity required for metastatic dissemination of basal-like breast carcinomas."
Moreno-Bueno G. , Salvador F. , Martin A. , Floristan A. , Cuevas E.P. , Santos V. , Montes A. , Morales S. , Castilla M.A. , Rojo-Sebastian A. , Martinez A. , Hardisson D. , Csiszar K. , Portillo F. , Peinado H. , Palacios J. , Cano A.
EMBO Mol. Med.3:528-544(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ROLE IN TUMOR PROGRESSION
14.

"The human lysyl oxidase-like 2 protein functions as an amine oxidase toward collagen and elastin."
Kim Y.M. , Kim E.C. , Kim Y.
Mol. Biol. Rep.38:145-149(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY;ENZYME REGULATION
15.

"The enzymatic activity of lysyl oxidas-like-2 (LOXL2) is not required for LOXL2-induced inhibition of keratinocyte differentiation."
Lugassy J. , Zaffryar-Eilot S. , Soueid S. , Mordoviz A. , Smith V. , Kessler O. , Neufeld G.
J. Biol. Chem.287:3541-3549(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF TYR-689
16.

"Lysyl oxidase-like 2 deaminates lysine 4 in histone H3."
Herranz N. , Dave N. , Millanes-Romero A. , Morey L. , Diaz V.M. , Lorenz-Fonfria V. , Gutierrez-Gallego R. , Jeronimo C. , Di Croce L. , Garcia de Herreros A. , Peiro S.
Mol. Cell46:369-376(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;MUTAGENESIS OF 626-HIS--HIS-628
17.

"Post-translational Modifications of Recombinant Human Lysyl Oxidase-like 2 (rhLOXL2) Secreted from Drosophila S2 Cells."
Xu L. , Go E.P. , Finney J. , Moon H. , Lantz M. , Rebecchi K. , Desaire H. , Mure M.
J. Biol. Chem.288:5357-5363(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY;ENZYME REGULATION;BIOPHYSICOCHEMICAL PROPERTIES;GLYCOSYLATION AT ASN-455 AND ASN-644;MUTAGENESIS OF ASN-455 AND ASN-644;CROSS-LINK FORMATION;SUBCELLULAR LOCATION

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