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Index > Protein center > LSM1(Gene name) > Human
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  • LSM1 (Gene name),
  • U6 snRNA-associated Sm-like protein LSm1 (Protein name ),  LSM1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    LSM1(CASM);
    Protein name:
    U6 snRNA-associated Sm-like protein LSm1;
    Alternative:
    Small nuclear ribonuclear CaSm;Cancer-associated Sm-like;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with SLBP. Interaction with SLBP occurs when histone mRNA is being rapidly degraded during the S phase. LSm subunits form a heteromer with a donut shape.
    Function:
    Plays a role in replication-dependent histone mRNA degradation. Binds specifically to the 3'-terminal U-tract of U6 snRNA.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    133
    Sequence:
    50:
    MNYMPGTASL | IEDIDKKHLV | LLRDGRTLIG | FLRSIDQFAN | LVLHQTVERI | 
    100:
    HVGKKYGDIP | RGIFVVRGEN | VVLLGEIDLE | KESDTPLQQV | SIEEILEEQR | 
    133:
    VEQQTKLEAE | KLKVQALKDR | GLSIPRADTL | DEY
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    Pfam:
    String:
    KEGG:
    UniGene:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human U6 snRNA-associated Sm-like protein LSm1
    ELISA Kit for Human U6 snRNA-associated Sm-like protein LSm1
    ELISA Kit for Human U6 snRNA-associated Sm-like protein LSm1
    CLIA Kit for Human U6 snRNA-associated Sm-like protein LSm1
    CLIA Kit for Human U6 snRNA-associated Sm-like protein LSm1
    CLIA Kit for Human U6 snRNA-associated Sm-like protein LSm1
    Polyclonal Antibody for Human U6 snRNA-associated Sm-like protein LSm1
    Polyclonal Antibody for Human U6 snRNA-associated Sm-like protein LSm1
    Polyclonal Antibody for Human U6 snRNA-associated Sm-like protein LSm1
    Monoclonal Antibody for Human U6 snRNA-associated Sm-like protein LSm1
    Monoclonal Antibody for Human U6 snRNA-associated Sm-like protein LSm1
    Monoclonal Antibody for Human U6 snRNA-associated Sm-like protein LSm1
    Protein for Human U6 snRNA-associated Sm-like protein LSm1
    Protein for Human U6 snRNA-associated Sm-like protein LSm1
    Protein for Human U6 snRNA-associated Sm-like protein LSm1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "CaSm: an Sm-like protein that contributes to the transformed state in cancer cells."
      Schweinfest C.W. , Graber M.W. , Chapman J.M. , Papas T.S. , Baron P.L. , Watson D.K.
      Cancer Res.57:2961-2965(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Sm and Sm-like proteins assemble in two related complexes of deep evolutionary origin."
      Salgado-Garrido J. , Bragado-Nilsson E. , Kandels-Lewis S. , Seraphin B.
      EMBO J.18:3451-3462(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Lymph node.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Substantia nigra.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Eye.
    6. 6.
      "Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'."
      Mullen T.E. , Marzluff W.F.
      Genes Dev.22:50-65(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN HISTONE MRNA DEGRADATION ACTIVITY;INTERACTION WITH SLBP
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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