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Index > Protein center > Lsm6(Gene name) > Mouse
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  • Lsm6 (Gene name),
  • U6 snRNA-associated Sm-like protein LSm6 (Protein name ),  LSM6_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Lsm6;
    Protein name:
    U6 snRNA-associated Sm-like protein LSm6;
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Component of the heptameric LSM1-LSM7 complex, which consists of LSM1, LSM2, LSM3, LSM4, LSM5, LSM6 and LSM7. Component of the heptameric LSM2-LSM8 complex, which consists of LSM2, LSM3, LSM4, LSM5, LSM6, LSM7 and LSM8. The LSm subunits form a seven-membered ring structure with a donut shape.
    Function:
    Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.
    Subcellular Location:
    Cytoplasm Nucleus
    Protein Attributes:
    Sequence length:
    80
    Sequence:
    50:
    MSLRKQTPSD | FLKQIIGRPV | VVKLNSGVDY | RGVLACLDGY | MNIALEQTEE | 
    80:
    YVNGQLKNKY | GDAFIRGNNV | LYISTQKRRM | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    UniGene:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse U6 snRNA-associated Sm-like protein LSm6
    ELISA Kit for Mouse U6 snRNA-associated Sm-like protein LSm6
    CLIA Kit for Mouse U6 snRNA-associated Sm-like protein LSm6
    CLIA Kit for Mouse U6 snRNA-associated Sm-like protein LSm6
    Polyclonal Antibody for Mouse U6 snRNA-associated Sm-like protein LSm6
    Polyclonal Antibody for Mouse U6 snRNA-associated Sm-like protein LSm6
    Monoclonal Antibody for Mouse U6 snRNA-associated Sm-like protein LSm6
    Monoclonal Antibody for Mouse U6 snRNA-associated Sm-like protein LSm6
    Protein for Mouse U6 snRNA-associated Sm-like protein LSm6
    Protein for Mouse U6 snRNA-associated Sm-like protein LSm6

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Mammary tumor.
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