Gene name:
LTB4R (BLT;BLT1;BLTR;CMKRL1;GPR16;P2RY7) ;
Protein name:
Leukotriene B4 receptor 1 (LTB4-R 1;LTB4-R1) ;
Alternative:
G-protein coupled receptor 16 ;Chemoattractant receptor-like 1 ;P2Y purinoceptor 7 (P2Y7) ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Protein Attributes:
50:
MNTTSSAAPP | SLGVEFISLL | AIILLSVALA | VGLPGNSFVV | WSILKRMQKR |
100:
SVTALMVLNL | ALADLAVLLT | APFFLHFLAQ | GTWSFGLAGC | RLCHYVCGVS |
150:
MYASVLLITA | MSLDRSLAVA | RPFVSQKLRT | KAMARRVLAG | IWVLSFLLAT |
200:
PVLAYRTVVP | WKTNMSLCFP | RYPSEGHRAF | HLIFEAVTGF | LLPFLAVVAS |
250:
YSDIGRRLQA | RRFRRSRRTG | RLVVLIILTF | AAFWLPYHVV | NLAEAGRALA |
300:
GQAAGLGLVG | KRLSLARNVL | IALAFLSSSV | NPVLYACAGG | GLLRSAGVGF |
350:
VAKLLEGTGS | EASSTRRGGS | LGQTARSGPA | ALEPGPSESL | TASSPLKLNE |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Bovine
Rat
ELISA Kit for Human LTB4-R 1
ELISA Kit for Human LTB4-R 1
ELISA Kit for Human LTB4-R 1
ELISA Kit for Human LTB4-R 1
CLIA Kit for Human LTB4-R 1
CLIA Kit for Human LTB4-R 1
CLIA Kit for Human LTB4-R 1
CLIA Kit for Human LTB4-R 1
Polyclonal Antibody for Human LTB4-R 1
Polyclonal Antibody for Human LTB4-R 1
Polyclonal Antibody for Human LTB4-R 1
Polyclonal Antibody for Human LTB4-R 1
Monoclonal Antibody for Human LTB4-R 1
Monoclonal Antibody for Human LTB4-R 1
Monoclonal Antibody for Human LTB4-R 1
Monoclonal Antibody for Human LTB4-R 1
Protein for Human LTB4-R 1
Protein for Human LTB4-R 1
Protein for Human LTB4-R 1
Protein for Human LTB4-R 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Molecular cloning of a novel P2 purinoceptor from human erythroleukemia cells."
Akbar G.K.M.
,
Dasari V.R.
,
Webb T.
,
Ayyanathan K.
,
Pillarisetti K.
,
Sandhu A.K.
,
Athwal R.S.
,
Daniel J.L.
,
Ashby B.
,
Barnard E.A.
,
Kunapuli S.P.
J. Biol. Chem.271:18363-18367(1996)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
7.
"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N.
,
Chen X.
,
Rolfs A.
,
Halleck A.
,
Hines L.
,
Eisenstein S.
,
Koundinya M.
,
Raphael J.
,
Moreira D.
,
Kelley T.
,
LaBaer J.
,
Lin Y.
,
Phelan M.
,
Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT PHE-346
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT PHE-346
tissue :
Lung .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION;MUTAGENESIS OF THR-308 AND SER-310