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Index > Protein center > LTB4R(Gene name) > Human
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  • LTB4R (Gene name),
  • Leukotriene B4 receptor 1 (Protein name ),  LT4R1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    LTB4R(BLT;BLT1;BLTR;CMKRL1;GPR16;P2RY7);
    Protein name:
    Leukotriene B4 receptor 1(LTB4-R 1;LTB4-R1);
    Alternative:
    G-protein coupled receptor 16;Chemoattractant receptor-like 1;P2Y purinoceptor 7(P2Y7);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    352
    Sequence:
    50:
    MNTTSSAAPP | SLGVEFISLL | AIILLSVALA | VGLPGNSFVV | WSILKRMQKR | 
    100:
    SVTALMVLNL | ALADLAVLLT | APFFLHFLAQ | GTWSFGLAGC | RLCHYVCGVS | 
    150:
    MYASVLLITA | MSLDRSLAVA | RPFVSQKLRT | KAMARRVLAG | IWVLSFLLAT | 
    200:
    PVLAYRTVVP | WKTNMSLCFP | RYPSEGHRAF | HLIFEAVTGF | LLPFLAVVAS | 
    250:
    YSDIGRRLQA | RRFRRSRRTG | RLVVLIILTF | AAFWLPYHVV | NLAEAGRALA | 
    300:
    GQAAGLGLVG | KRLSLARNVL | IALAFLSSSV | NPVLYACAGG | GLLRSAGVGF | 
    350:
    VAKLLEGTGS | EASSTRRGGS | LGQTARSGPA | ALEPGPSESL | TASSPLKLNE | 
    352:
    LN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    UniGene:
    String:
    Pfam:
    KEGG:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human LTB4-R 1
    Cat.:
    E10103h
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    96T
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    ELISA Kit for Human LTB4-R 1
    Cat.:
    E10103m
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    Packing:
    96T
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    ELISA Kit for Human LTB4-R 1
    MSDS:
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    ELISA Kit for Human LTB4-R 1
    Cat.:
    E10103r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human LTB4-R 1
    MSDS:
    Please sign in first.
    CLIA Kit for Human LTB4-R 1
    Cat.:
    U10103m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    CLIA Kit for Human LTB4-R 1
    Cat.:
    U10103r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human LTB4-R 1
    Cat.:
    U10103h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human LTB4-R 1
    Cat.:
    P10103Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human LTB4-R 1
    Polyclonal Antibody for Human LTB4-R 1
    Polyclonal Antibody for Human LTB4-R 1
    Monoclonal Antibody for Human LTB4-R 1
    Monoclonal Antibody for Human LTB4-R 1
    Monoclonal Antibody for Human LTB4-R 1
    Monoclonal Antibody for Human LTB4-R 1
    Protein for Human LTB4-R 1
    Protein for Human LTB4-R 1
    Protein for Human LTB4-R 1
    Protein for Human LTB4-R 1

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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis."
      Yokomizo T. , Izumi T. , Chang K. , Takuwa Y. , Shimizu T.
      Nature387:620-624(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      "Cloning of cDNA encoding a putative chemoattractant receptor."
      Owman C.S.O. , Nilsson C. , Lolait S.J.
      Genomics37:187-194(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    5. 5.
      "Cell-specific transcriptional regulation of human leukotriene B(4) receptor gene."
      Kato K. , Yokomizo T. , Izumi T. , Shimizu T.
      J. Exp. Med.192:413-420(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    6. 6.
      "Isolation of complete coding sequence for leukotriene B4 receptor (LTB4R)."
      Kopatz S.A. , Aronstam R.S. , Sharma S.V.
      Submitted (2003-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    7. 7.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT PHE-346
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT PHE-346
      tissue: Lung.
    9. 9.
      "Threonine 308 within a putative casein kinase 2 site of the cytoplasmic tail of leukotriene B(4) receptor (BLT1) is crucial for ligand-induced, G-protein-coupled receptor-specific kinase 6-mediated desensitization."
      Gaudreau R. , Le Gouill C. , Venne M.-H. , Stankova J. , Rola-Pleszczynski M.
      J. Biol. Chem.277:31567-31576(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION;MUTAGENESIS OF THR-308 AND SER-310
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