LTBP2 ELISA Kit for Human(Homo sapiens) | EIAab.comLTBP2 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > LTBP2(Gene name) > Human

LTBP2 (Gene name),

Latent-transforming growth factor beta-binding protein 2 (Protein name ), LTBP2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

LTBP2(C14orf141;LTBP3);

Protein name:

Latent-transforming growth factor beta-binding protein 2(LTBP-2);

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Forms part of the large latent transforming growth factor beta precursor complex; removal is essential for activation of complex.

Function:

May play an integral structural role in elastic-fiber architectural organization and/or assembly.

Subcellular Location:

Secreted Localized in nuchal ligament and aorta to the fibrillin-containing, microfibrillar component of elastic fibers.

Protein Attributes:

Sequence length:

1821

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1821:

RCHCSPGYVA | EAGPPHCTAK | E

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00008

STRING:

9606.ENSP00000261978

KEGG:

hsa:4053

String:

Q14767

UniGene:

Hs.512776

SMR:

Q14767

MIM:

251750

Uniprot:

Q14767

FOR

ELISA Kit for Human LTBP-2

Cat.:

E1630m

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Packing:

96T

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ELISA Kit for Human LTBP-2

Cat.:

E1630h

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Manual:

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96T

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ELISA Kit for Human LTBP-2

Cat.:

E1630r

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MSDS:

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Packing:

96T

ELISA Kit for Human LTBP-2

Cat.:

E1630b

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MSDS:

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Packing:

96T

CLIA Kit for Human LTBP-2

Cat.:

U1630m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human LTBP-2

Cat.:

U1630h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human LTBP-2

Cat.:

U1630r

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human LTBP-2

Cat.:

U1630b

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human LTBP-2

Cat.:

P1630Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human LTBP-2

Cat.:

P1630Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human LTBP-2

Cat.:

P1630Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human LTBP-2

Protein for Human LTBP-2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Identification and characterization of LTBP-2, a novel latent transforming growth factor-beta-binding protein."
Moren A. , Olofsson A. , Stenman G. , Sahlin P. , Kanzaki T. , Claesson-Welsh L. , ten Dijke P. , Miyazono K. , Heldin C.
J. Biol. Chem.269:32469-32478(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];CHARACTERIZATION
tissue: Foreskin fibroblast.
2.

"Analysis of the human gene encoding latent transforming growth factor-beta-binding protein-2."
Bashir M.M. , Han M.-D. , Abrams W.R. , Tucker T. , Ma R.-I. , Gibson M. , Ritty T. , Mecham R. , Rosenbloom J.
Int. J. Biochem. Cell Biol.28:531-542(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"The DNA sequence and analysis of human chromosome 14."
Heilig R. , Eckenberg R. , Petit J.-L. , Fonknechten N. , Da Silva C. , Cattolico L. , Levy M. , Barbe V. , De Berardinis V. , Ureta-Vidal A. , Pelletier E. , Vico V. , Anthouard V. , Rowen L. , Madan A. , Qin S. , Sun H. , Du H. , more...
Nature421:601-607(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-beta."
Saharinen J. , Keski-Oja J.
Mol. Biol. Cell11:2691-2704(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: LACK OF INTERACTION WITH TGFB1;MUTAGENESIS OF 1449-ASP-LEU-1450
5.

"Latent transforming growth factor-beta binding proteins (LTBPs) --structural extracellular matrix proteins for targeting TGF-beta action."
Saharinen J. , Hyytiainen M. , Taipale J. , Keski-Oja J.
Cytokine Growth Factor Rev.10:99-117(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
6.

"The latent transforming growth factor beta binding protein (LTBP) family."
Oklu R. , Hesketh R.
Biochem. J.352:601-610(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
7.

"Null mutations in LTBP2 cause primary congenital glaucoma."
Ali M. , McKibbin M. , Booth A. , Parry D.A. , Jain P. , Riazuddin S.A. , Hejtmancik J.F. , Khan S.N. , Firasat S. , Shires M. , Gilmour D.F. , Towns K. , Murphy A.L. , Azmanov D. , Tournev I. , Cherninkova S. , Jafri H. , Raashid Y. , more...
Am. J. Hum. Genet.84:664-671(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN GLC3D
8.

"A homozygous mutation in LTBP2 causes isolated microspherophakia."
Kumar A. , Duvvari M.R. , Prabhakaran V.C. , Shetty J.S. , Murthy G.J. , Blanton S.H.
Hum. Genet.128:365-371(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN MSPKA
9.

"LTBP-2 has multiple heparin/heparan sulfate binding sites."
Parsi M.K. , Adams J.R. , Whitelock J. , Gibson M.A.
Matrix Biol.29:393-401(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: HEPARIN-BINDING REGIONS;INTERACTION WITH SDC4
10.

"LTBP2 mutations cause Weill-Marchesani and Weill-Marchesani-like syndrome and affect disruptions in the extracellular matrix."
Haji-Seyed-Javadi R. , Jelodari-Mamaghani S. , Paylakhi S.H. , Yazdani S. , Nilforushan N. , Fan J.B. , Klotzle B. , Mahmoudi M.J. , Ebrahimian M.J. , Chelich N. , Taghiabadi E. , Kamyab K. , Boileau C. , Paisan-Ruiz C. , Ronaghi M. , Elahi E.
Hum. Mutat.33:1182-1187(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT WMS3 MET-1177

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