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Index > Protein center > Mid1ip1(Gene name) > Mouse
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  • Mid1ip1 (Gene name),
  • Mid1-interacting protein 1 (Protein name ),  M1IP1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Mid1ip1(Mig12);
    Protein name:
    Mid1-interacting protein 1;
    Alternative:
    Mid1-interacting G12-like protein;Gastrulation-specific G12-like protein;Spot 14-related protein(S14R;Spot 14-R);Protein STRAIT11499 homolog;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer in the absence of THRSP. Heterodimer with THRSP. The homodimer interacts with ACACA and ACACB. Promotes polymerization of Acetyl-CoA carboxylase to form complexes that contain MID1IP1 and ACACA and/or ACACB. Interaction with THRSP interferes with ACACA binding.
    Function:
    Plays a role in the regulation of lipogenesis in liver. Up-regulates ACACA enzyme activity. Required for efficient lipid biosynthesis, including triacylglycerol, diacylglycerol and phospholipid. Involved in stabilization of microtubules.
    Subcellular Location:
    Nucleus Cytoplasm Cytoplasm cytoskeleton Associated with microtubules.
    Protein Attributes:
    Sequence length:
    182
    Sequence:
    50:
    MMQICDTYNQ | KHSLFNAMNR | FIGAVNNMDQ | TVMVPSLLRD | VPLSEPEIDE | 
    100:
    VSVEVGGSGG | CLEERTTPAP | SPGSANESFF | APSRDMYSHY | VLLKSIRNDI | 
    150:
    EWGVLHQPSS | PPAGSEESTW | KPKDILVGLS | HLESADAGEE | DLEQQFHYHL | 
    182:
    RGLHTVLSKL | TRKANILTNR | YKQEIGFSNW | GH
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    SMR:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Mid1-interacting protein 1
    ELISA Kit for Mouse Mid1-interacting protein 1
    ELISA Kit for Mouse Mid1-interacting protein 1
    CLIA Kit for Mouse Mid1-interacting protein 1
    CLIA Kit for Mouse Mid1-interacting protein 1
    CLIA Kit for Mouse Mid1-interacting protein 1
    Polyclonal Antibody for Mouse Mid1-interacting protein 1
    Polyclonal Antibody for Mouse Mid1-interacting protein 1
    Polyclonal Antibody for Mouse Mid1-interacting protein 1
    Monoclonal Antibody for Mouse Mid1-interacting protein 1
    Monoclonal Antibody for Mouse Mid1-interacting protein 1
    Monoclonal Antibody for Mouse Mid1-interacting protein 1
    Protein for Mouse Mid1-interacting protein 1
    Protein for Mouse Mid1-interacting protein 1
    Protein for Mouse Mid1-interacting protein 1

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    Linearity
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    References
    1. 1.
      "Mig12, a novel Opitz syndrome gene product partner, is expressed in the embryonic ventral midline and co-operates with Mid1 to bundle and stabilize microtubules."
      Berti C. , Fontanella B. , Ferrentino R. , Meroni G.
      BMC Cell Biol.5:9-9(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;INTERACTION WITH MID1
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Embryo.
      tissue: Embryonic head.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Colon.
      tissue: Mesenchymal cell.
    4. 4.
      "The Spot 14 protein is required for de novo lipid synthesis in the lactating mammary gland."
      Zhu Q. , Anderson G.W. , Mucha G.T. , Parks E.J. , Metkowski J.K. , Mariash C.N.
      Endocrinology146:3343-3350(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION;TISSUE SPECIFICITY
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-74;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    6. 6.
      "Induced polymerization of mammalian acetyl-CoA carboxylase by MIG12 provides a tertiary level of regulation of fatty acid synthesis."
      Kim C.W. , Moon Y.A. , Park S.W. , Cheng D. , Kwon H.J. , Horton J.D.
      Proc. Natl. Acad. Sci. U.S.A.107:9626-9631(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH ACACA AND ACACB;SUBUNIT;INDUCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH THRSP AND ACACA;SUBCELLULAR LOCATION
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