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Index > Protein center > Map3k12(Gene name) > Rat
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  • Map3k12 (Gene name),
  • Mitogen-activated protein kinase kinase kinase 12 (Protein name ),  M3K12_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Map3k12(Muk);
    Protein name:
    Mitogen-activated protein kinase kinase kinase 12;
    Alternative:
    Leucine-zipper protein kinase(ZPK);Dual leucine zipper bearing kinase(DLK);Mixed lineage kinase;MAPK-upstream kinase(MUK);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with MBIP.
    Function:
    May be an activator of the JNK/SAPK pathway. Phosphorylates beta-casein, histone 1 and myelin basic protein in vitro.
    Subcellular Location:
    Cytoplasm Membrane Peripheral membrane protein
    Protein Attributes:
    Sequence length:
    888
    Sequence:
    50:
    MACLHETRTP | SPSFGGFVST | LSEASMRKLD | PDTSDCTPEK | DLTPTQCVLR | 
    100:
    DVVPLGGQGG | GGPSPSPGGE | PPPEPFANSV | LQLHEQDTGG | PGGATGSPES | 
    150:
    RASRVRADEV | RLQCQSGSGF | LEGLFGCLRP | VWTMIGKAYS | TEHKQQQEDL | 
    200:
    WEVPFEEILD | LQWVGSGAQG | AVFLGRFHGE | EVAVKKVRDL | KETDIKHLRK | 
    250:
    LKHPNIITFK | GVCTQAPCYC | ILMEFCAQGQ | LYEVLRAGRP | VTPSLLVDWS | 
    300:
    MGIAGGMNYL | HLHKIIHRDL | KSPNMLITYD | DVVKISDFGT | SKELSDKSTK | 
    350:
    MSFAGTVAWM | APEVIRNEPV | SEKVDIWSFG | VVLWELLTGE | IPYKDVDSSA | 
    400:
    IIWGVGSNSL | HLPVPSSCPD | GFKILLRQCW | NRKPRNRPSF | RQILLHLDIA | 
    450:
    SADVLSTPQE | TYFKSQAEWR | EEVKLHFEKI | KSEGTCLHRL | EEELVMRRRE | 
    500:
    ELRHALDIRE | HYERKLERAN | NLYMELNALM | LQLELKEREL | LRREQALERR | 
    550:
    CPGLLKSHTS | RSLLHGNTME | KLIKKRNVPQ | KLSPHSKRPD | ILKTESLLPK | 
    600:
    LDAALSGVGL | PGCPKAPPSP | GRSRRGKTRH | RKASAKGSCG | DLPGLRAALP | 
    650:
    PHEPGGLGSP | GGLGVGPTAW | DASPPALRGL | HHDLLLRKMS | SSSPDLLSAA | 
    700:
    LGARGRGATG | GARDPGSPPP | PQGDTPPSEG | SAPGSTSPDS | PGGAKGEPPP | 
    750:
    PVGPGEGVGL | LGTGREGTTG | RGGSRAGYQH | LTPAALLYRA | AVTRSQKRGI | 
    800:
    SSEEEEGEVD | SEVELPPSQR | WPQGPNMRQS | LSTFSSENPS | DVEEGTASEP | 
    850:
    SPSGTPEVGS | TNTDERPDER | SDDMCSQGSE | IPLDLPTSEV | VPERETSSLP | 
    888:
    MQHQDDQGPN | PEDSDCDSTE | LDNSNSIDAL | PPPASLPP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    KEGG:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Mitogen-activated protein kinase kinase kinase 12
    ELISA Kit for Rat Mitogen-activated protein kinase kinase kinase 12
    ELISA Kit for Rat Mitogen-activated protein kinase kinase kinase 12
    CLIA Kit for Rat Mitogen-activated protein kinase kinase kinase 12
    CLIA Kit for Rat Mitogen-activated protein kinase kinase kinase 12
    CLIA Kit for Rat Mitogen-activated protein kinase kinase kinase 12
    Polyclonal Antibody for Rat Mitogen-activated protein kinase kinase kinase 12
    Polyclonal Antibody for Rat Mitogen-activated protein kinase kinase kinase 12
    Polyclonal Antibody for Rat Mitogen-activated protein kinase kinase kinase 12
    Monoclonal Antibody for Rat Mitogen-activated protein kinase kinase kinase 12
    Monoclonal Antibody for Rat Mitogen-activated protein kinase kinase kinase 12
    Monoclonal Antibody for Rat Mitogen-activated protein kinase kinase kinase 12
    Protein for Rat Mitogen-activated protein kinase kinase kinase 12
    Protein for Rat Mitogen-activated protein kinase kinase kinase 12
    Protein for Rat Mitogen-activated protein kinase kinase kinase 12

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    Precision
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    Linearity
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    References
    1. 1.
      "Activation of the JNK pathway by distantly related protein kinases, MEKK and MUK."
      Hirai S. , Izawa M. , Osada S. , Spyrou G. , Ohno S.
      Oncogene12:641-650(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      Lubec G. , Kang S.U.
      Submitted (2007-07) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 440-448;IDENTIFICATION BY MASS SPECTROMETRY
      strain: Sprague-Dawley.
      tissue: Brain.
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