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Index > Protein center > MAP4K3(Gene name) > Human
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  • MAP4K3 (Gene name),
  • Mitogen-activated protein kinase kinase kinase kinase 3 (Protein name ),  M4K3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    MAP4K3(RAB8IPL1);
    Protein name:
    Mitogen-activated protein kinase kinase kinase kinase 3;
    Alternative:
    MAPK/ERK kinase kinase kinase 3(MEK kinase kinase 3;MEKKK 3);Germinal center kinase-related protein kinase(GLK);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with SH3GL2. Interaction appears to regulate MAP4K3-mediated JNK activation.
    Function:
    May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    894
    Sequence:
    50:
    MNPGFDLSRR | NPQEDFELIQ | RIGSGTYGDV | YKARNVNTGE | LAAIKVIKLE | 
    100:
    PGEDFAVVQQ | EIIMMKDCKH | PNIVAYFGSY | LRRDKLWICM | EFCGGGSLQD | 
    150:
    IYHVTGPLSE | LQIAYVSRET | LQGLYYLHSK | GKMHRDIKGA | NILLTDNGHV | 
    200:
    KLADFGVSAQ | ITATIAKRKS | FIGTPYWMAP | EVAAVERKGG | YNQLCDLWAV | 
    250:
    GITAIELAEL | QPPMFDLHPM | RALFLMTKSN | FQPPKLKDKM | KWSNSFHHFV | 
    300:
    KMALTKNPKK | RPTAEKLLQH | PFVTQHLTRS | LAIELLDKVN | NPDHSTYHDF | 
    350:
    DDDDPEPLVA | VPHRIHSTSR | NVREEKTRSE | ITFGQVKFDP | PLRKETEPHH | 
    400:
    ELPDSDGFLD | SSEEIYYTAR | SNLDLQLEYG | QGHQGGYFLG | ANKSLLKSVE | 
    450:
    EELHQRGHVA | HLEDDEGDDD | ESKHSTLKAK | IPPPLPPKPK | SIFIPQEMHS | 
    500:
    TEDENQGTIK | RCPMSGSPAK | PSQVPPRPPP | PRLPPHKPVA | LGNGMSSFQL | 
    550:
    NGERDGSLCQ | QQNEHRGTNL | SRKEKKDVPK | PISNGLPPTP | KVHMGACFSK | 
    600:
    VFNGCPLKIH | CASSWINPDT | RDQYLIFGAE | EGIYTLNLNE | LHETSMEQLF | 
    650:
    PRRCTWLYVM | NNCLLSISGK | ASQLYSHNLP | GLFDYARQMQ | KLPVAIPAHK | 
    700:
    LPDRILPRKF | SVSAKIPETK | WCQKCCVVRN | PYTGHKYLCG | ALQTSIVLLE | 
    750:
    WVEPMQKFML | IKHIDFPIPC | PLRMFEMLVV | PEQEYPLVCV | GVSRGRDFNQ | 
    800:
    VVRFETVNPN | STSSWFTESD | TPQTNVTHVT | QLERDTILVC | LDCCIKIVNL | 
    850:
    QGRLKSSRKL | SSELTFDFQI | ESIVCLQDSV | LAFWKHGMQG | RSFRSNEVTQ | 
    894:
    EISDSTRIFR | LLGSDRVVVL | ESRPTDNPTA | NSNLYILAGH | ENSY
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    UniGene:
    SMR:
    KEGG:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Mitogen-activated protein kinase kinase kinase kinase 3
    ELISA Kit for Human Mitogen-activated protein kinase kinase kinase kinase 3
    ELISA Kit for Human Mitogen-activated protein kinase kinase kinase kinase 3
    CLIA Kit for Human Mitogen-activated protein kinase kinase kinase kinase 3
    CLIA Kit for Human Mitogen-activated protein kinase kinase kinase kinase 3
    CLIA Kit for Human Mitogen-activated protein kinase kinase kinase kinase 3
    Polyclonal Antibody for Human Mitogen-activated protein kinase kinase kinase kinase 3
    Polyclonal Antibody for Human Mitogen-activated protein kinase kinase kinase kinase 3
    Polyclonal Antibody for Human Mitogen-activated protein kinase kinase kinase kinase 3
    Monoclonal Antibody for Human Mitogen-activated protein kinase kinase kinase kinase 3
    Monoclonal Antibody for Human Mitogen-activated protein kinase kinase kinase kinase 3
    Monoclonal Antibody for Human Mitogen-activated protein kinase kinase kinase kinase 3
    Protein for Human Mitogen-activated protein kinase kinase kinase kinase 3
    Protein for Human Mitogen-activated protein kinase kinase kinase kinase 3
    Protein for Human Mitogen-activated protein kinase kinase kinase kinase 3

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase."
      Diener K. , Wang X.S. , Chen C. , Meyer C.F. , Keesler G. , Zukowski M. , Tan T.-H. , Yao Z.
      Proc. Natl. Acad. Sci. U.S.A.94:9687-9692(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION;TISSUE SPECIFICITY;MUTAGENESIS OF LYS-48
      tissue: Macrophage.
      tissue: Skeletal muscle.
    2. 2.
      "Physical/genetic map of the 2p22-2p21 region on chromosome 2."
      Gorry M.C. , Zhang Y. , Marks J.J. , Suppe B. , Hart S. , Cortelli J. , Pallos D. , Hart T.C.
      Submitted (2001-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORMS 1 AND 3)
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      tissue: Testis.
    5. 5.
      Edwards J. , Wohldmann P. , Hawkins M. , Harkins R.
      Submitted (1999-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 1-712 (ISOFORM 1)
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-398;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    7. 7.
      "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
      Bienvenut W.V. , Sumpton D. , Martinez A. , Lilla S. , Espagne C. , Meinnel T. , Giglione C.
      Mol. Cell. Proteomics11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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