Map4k4 ELISA Kit for Mouse(Mus musculus) | EIAab.comMap4k4 ELISA Kit for Mouse(Mus musculus)

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Map4k4 (Gene name),

Mitogen-activated protein kinase kinase kinase kinase 4 (Protein name ), M4K4_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Map4k4(Nik);

Protein name:

Mitogen-activated protein kinase kinase kinase kinase 4;

Alternative:

MAPK/ERK kinase kinase kinase 4(MEK kinase kinase 4;MEKKK 4);HPK/GCK-like kinase HGK;Nck-interacting kinase;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with the SH3 domain of the adapter proteins Nck. Interacts (via its CNH regulatory domain) with ATL1 (via the N-terminal region). Interacts with RAP2A (GTP-bound form preferentially).

Function:

Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

1233

Sequence:

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1233:

CGRNDKVFFS | SVRSGGSSQV | YFMTLGRTSL | LSW

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

mmu:26921

UniGene:

Mm.491139

SMR:

P97820

UniGene:

Mm.485049

String:

P97820

Pfam:

PF00780

Uniprot:

P97820

FOR

ELISA Kit for Mouse Mitogen-activated protein kinase kinase kinase kinase 4

Cat.:

E16378m

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Mouse Mitogen-activated protein kinase kinase kinase kinase 4

Cat.:

E16378h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Mitogen-activated protein kinase kinase kinase kinase 4

Cat.:

U16378h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Mitogen-activated protein kinase kinase kinase kinase 4

Cat.:

U16378m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Mitogen-activated protein kinase kinase kinase kinase 4

Cat.:

P16378Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Mitogen-activated protein kinase kinase kinase kinase 4

Cat.:

P16378Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Mitogen-activated protein kinase kinase kinase kinase 4

Protein for Mouse Mitogen-activated protein kinase kinase kinase kinase 4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain."
Su Y.-C. , Han J. , Xu S. , Cobb M. , Skolnik E.Y.
EMBO J.16:1279-1290(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY
tissue: Brain.
tissue: Embryo.
2.

"Nck-interacting Ste20 kinase couples Eph receptors to c-Jun N-terminal kinase and integrin activation."
Becker E. , Huynh-Do U. , Holland S. , Pawson T. , Daniel T.O. , Skolnik E.Y.
Mol. Cell. Biol.20:1537-1545(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH NCK
3.

"Phosphoproteomic analysis of the developing mouse brain."
Ballif B.A. , Villen J. , Beausoleil S.A. , Schwartz D. , Gygi S.P.
Mol. Cell. Proteomics3:1093-1101(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic brain.

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