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Index > Protein center > MACC1(Gene name) > Human
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  • MACC1 (Gene name),
  • Metastasis-associated in colon cancer protein 1 (Protein name ),  MACC1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    MACC1;
    Protein name:
    Metastasis-associated in colon cancer protein 1;
    Alternative:
    SH3 domain-containing protein 7a5;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with FASLG.
    Function:
    Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling. Promotes cell motility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and metastasis in vivo.
    Subcellular Location:
    Cytoplasm Nucleus Mainly found in the cytoplasm in non-metastasizing tumors.
    Protein Attributes:
    Sequence length:
    852
    Sequence:
    50:
    MLITERKHFR | SGRIAQSMSE | ANLIDMEAGK | LSKSCNITEC | QDPDLLHNWP | 
    100:
    DAFTLRGNNA | SKVANPFWNQ | LSASNPFLDD | ITQLRNNRKR | NNISILKEDP | 
    150:
    FLFCREIENG | NSFDSSGDEL | DVHQLLRQTS | SRNSGRSKSV | SELLDILDDT | 
    200:
    AHAHQSIHNS | DQILLHDLEW | LKNDREAYKM | AWLSQRQLAR | SCLDLNTISQ | 
    250:
    SPGWAQTQLA | EVTIACKVNH | QGGSVQLPES | DITVHVPQGH | VAVGEFQEVS | 
    300:
    LRAFLDPPHM | LNHDLSCTVS | PLLEIMLGNL | NTMEALLLEM | KIGAEVRKDP | 
    350:
    FSQVMTEMVC | LHSLGKEGPF | KVLSNCYIYK | DTIQVKLIDL | SQVMYLVVAA | 
    400:
    QAKALPSPAA | TIWDYIHKTT | SIGIYGPKYI | HPSFTVVLTV | CGHNYMPGQL | 
    450:
    TISDIKKGGK | NISPVVFQLW | GKQSFLLDKP | QDLSISIFSC | DPDFEVKTEG | 
    500:
    ERKEIKQKQL | EAGEVVHQQF | LFSLVEHREM | HLFDFCVQVE | PPNGEPVAQF | 
    550:
    SITTPDPTPN | LKRLSNLPGY | LQKKEEIKSA | PLSPKILVKY | PTFQDKTLNF | 
    600:
    SNYGVTLKAV | LRQSKIDYFL | EYFKGDTIAL | LGEGKVKAIG | QSKVKEWYVG | 
    650:
    VLRGKIGLVH | CKNVKVISKE | QVMFMSDSVF | TTRNLLEQIV | LPLKKLTYIY | 
    700:
    SVVLTLVSEK | VYDWKVLADV | LGYSHLSLED | FDQIQADKES | EKVSYVIKKL | 
    750:
    KEDCHTERNT | RKFLYELIVA | LLKMDCQELV | ARLIQEAAVL | TSAVKLGKGW | 
    800:
    RELAEKLVRL | TKQQMEAYEI | PHRGNTGDVA | VEMMWKPAYD | FLYTWSAHYG | 
    850:
    NNYRDVLQDL | QSALDRMKNP | VTKHWRELTG | VLILVNSLEV | LRVTAFSTSE | 
    852:
    EV
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    String:
    MIM:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Metastasis-associated in colon cancer protein 1
    Cat.:
    E1546h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Metastasis-associated in colon cancer protein 1
    Cat.:
    U1546h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Metastasis-associated in colon cancer protein 1
    Cat.:
    P1546Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Metastasis-associated in colon cancer protein 1
    Protein for Human Metastasis-associated in colon cancer protein 1

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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis."
      Stein U. , Walther W. , Arlt F. , Schwabe H. , Smith J. , Fichtner I. , Birchmeier W. , Schlag P.M.
      Nat. Med.15:59-67(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
      tissue: Colon carcinoma.
      tissue: Trachea.
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS VAL-31; LEU-515 AND THR-804
      tissue: Tongue.
    3. 4.
      "The DNA sequence of human chromosome 7."
      Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
      Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
    6. 7.
      "Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening."
      Voss M. , Lettau M. , Janssen O.
      BMC Immunol.10:53-53(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FASLG
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