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Index > Protein center > MACROD2(Gene name) > Human
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  • MACROD2 (Gene name),
  • MACRO domain-containing protein 2 (Protein name ),  MACD2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    MACROD2(C20orf133);
    Protein name:
    MACRO domain-containing protein 2;
    Alternative:
    [Protein ADP-ribosylglutamate] hydrolase;O-acetyl-ADP-ribose deacetylase;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    448
    Sequence:
    50:
    MYPSNKKKKV | WREEKERLLK | MTLEERRKEY | LRDYIPLNSI | LSWKEEMKGK | 
    100:
    GQNDEENTQE | TSQVKKSLTE | KVSLYRGDIT | LLEVDAIVNA | ANASLLGGGG | 
    150:
    VDGCIHRAAG | PCLLAECRNL | NGCDTGHAKI | TCGYDLPAKY | VIHTVGPIAR | 
    200:
    GHINGSHKED | LANCYKSSLK | LVKENNIRSV | AFPCISTGIY | GFPNEPAAVI | 
    250:
    ALNTIKEWLA | KNHHEVDRII | FCVFLEVDFK | IYKKKMNEFF | SVDDNNEEEE | 
    300:
    DVEMKEDSDE | NGPEEKQSVE | EMEEQSQDAD | GVNTVTVPGP | ASEEAVEDCK | 
    350:
    DEDFAKDENI | TKGGEVTDHS | VRDQDHPDGQ | ENDSTKNEIK | IETESQSSYM | 
    400:
    ETEELSSNQE | DAVIVEQPEV | IPLTEDQEEK | EGEKAPGEDT | PRMPGKSEGS | 
    448:
    SDLENTPGPD | VEMNSQVDKV | NDPTESQQED | QLIAGAQDEA | KEQRNGTK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    Pfam:
    MIM:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human MACRO domain-containing protein 2
    ELISA Kit for Human MACRO domain-containing protein 2
    CLIA Kit for Human MACRO domain-containing protein 2
    CLIA Kit for Human MACRO domain-containing protein 2
    Polyclonal Antibody for Human MACRO domain-containing protein 2
    Polyclonal Antibody for Human MACRO domain-containing protein 2
    Monoclonal Antibody for Human MACRO domain-containing protein 2
    Monoclonal Antibody for Human MACRO domain-containing protein 2
    Protein for Human MACRO domain-containing protein 2
    Protein for Human MACRO domain-containing protein 2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Homozygous deletions and chromosome amplifications in human pancreatic cancer cell lines identified using a single nucleotide polymorphism array."
      Lin L.-J. , Asaoka Y. , Tada M. , Muroyama R. , Tanaka Y. , Ohta M. , Seto M. , Kanai F. , Zheng C.-Q. , Omata M.
      Submitted (2006-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Thymus.
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 5);VARIANT ILE-58
      tissue: Testis.
    3. 3.
      "The DNA sequence and comparative analysis of human chromosome 20."
      Deloukas P. , Matthews L.H. , Ashurst J.L. , Burton J. , Gilbert J.G.R. , Jones M. , Stavrides G. , Almeida J.P. , Babbage A.K. , Bagguley C.L. , Bailey J. , Barlow K.F. , Bates K.N. , Beard L.M. , Beare D.M. , Beasley O.P. , Bird C.P. , Blakey S.E. , more...
      Nature414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 4 AND 6)
      tissue: Lung.
    6. 6.
      "Identification of macrodomain proteins as novel O-acetyl-ADP-ribose deacetylases."
      Chen D. , Vollmar M. , Rossi M.N. , Phillips C. , Kraehenbuehl R. , Slade D. , Mehrotra P.V. , von Delft F. , Crosthwaite S.K. , Gileadi O. , Denu J.M. , Ahel I.
      J. Biol. Chem.286:13261-13271(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY;BIOPHYSICOCHEMICAL PROPERTIES
    7. 7.
      "A family of macrodomain proteins reverses cellular mono-ADP-ribosylation."
      Jankevicius G. , Hassler M. , Golia B. , Rybin V. , Zacharias M. , Timinszky G. , Ladurner A.G.
      Nat. Struct. Mol. Biol.20:508-514(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.55 ANGSTROMS) OF 7-243 IN COMPLEX WITH ADP-RIBOSE;FUNCTION;ENZYME REGULATION;INTERACTION WITH PARP1;MUTAGENESIS OF ASN-92; ASP-102 AND GLY-188
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