Mxd4 ELISA Kit for Mouse(Mus musculus) | EIAab.comMxd4 ELISA Kit for Mouse(Mus musculus)

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Mxd4 (Gene name),

Max dimerization protein 4 (Protein name ), MAD4_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

Mxd4(Mad4);

Protein name:

Max dimerization protein 4(Max dimerizer 4);

Alternative:

Max-interacting transcriptional repressor MAD4;Max-associated protein 4;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX. Interacts with SIN3A AND SIN3B. Interacts with RNF17.

Function:

Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

209

Sequence:

50:

100:

150:

200:

209:

RRPGCPGLS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q60948

UniGene:

Mm.259260

String:

Q60948

Pfam:

PF00010

Uniprot:

Q60948

FOR

ELISA Kit for Mouse Max dimerizer 4

CLIA Kit for Mouse Max dimerizer 4

Polyclonal Antibody for Mouse Max dimerizer 4

Monoclonal Antibody for Mouse Max dimerizer 4

Protein for Mouse Max dimerizer 4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation."
Hurlin P.J. , Queva C. , Koskinen P.J. , Steingrimsson E. , Ayer D.E. , Copeland N.G. , Jenkins N.A. , Eisenman R.N.
EMBO J.14:5646-5659(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;DEVELOPMENTAL STAGE;SUBUNIT;INTERACTION WITH SIN3A AND SIN3B
strain: AB1.
tissue: Embryonic stem cell.
2.

Hurlin P.J. , Queva C. , Koskinen P.J. , Steingrimsson E. , Ayer D.E. , Copeland N.G. , Jenkins N.A. , Eisenman R.N.
EMBO J.15:2030-2030(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
3.

"Mmip-2, a novel RING finger protein that interacts with mad members of the Myc oncoprotein network."
Yin X.-Y. , Gupta K. , Prochownik E.V.
Oncogene18:6621-6634(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RNF17

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