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Index > Protein center > MAGEA3(Gene name) > Human
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  • MAGEA3 (Gene name),
  • Melanoma-associated antigen 3 (Protein name ),  MAGA3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    MAGEA3(MAGE3);
    Protein name:
    Melanoma-associated antigen 3;
    Alternative:
    Cancer/testis antigen 1.3(CT1.3);Antigen MZ2-D;MAGE-3 antigen;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    314
    Sequence:
    50:
    MPLEQRSQHC | KPEEGLEARG | EALGLVGAQA | PATEEQEAAS | SSSTLVEVTL | 
    100:
    GEVPAAESPD | PPQSPQGASS | LPTTMNYPLW | SQSYEDSSNQ | EEEGPSTFPD | 
    150:
    LESEFQAALS | RKVAELVHFL | LLKYRAREPV | TKAEMLGSVV | GNWQYFFPVI | 
    200:
    FSKASSSLQL | VFGIELMEVD | PIGHLYIFAT | CLGLSYDGLL | GDNQIMPKAG | 
    250:
    LLIIVLAIIA | REGDCAPEEK | IWEELSVLEV | FEGREDSILG | DPKKLLTQHF | 
    300:
    VQENYLEYRQ | VPGSDPACYE | FLWGPRALVE | TSYVKVLHHM | VKISGGPHIS | 
    314:
    YPPLHEWVLR | EGEE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    Pfam:
    UniGene:
    KEGG:
    String:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Melanoma-associated antigen 3
    CLIA Kit for Human Melanoma-associated antigen 3
    Polyclonal Antibody for Human Melanoma-associated antigen 3
    Monoclonal Antibody for Human Melanoma-associated antigen 3
    Protein for Human Melanoma-associated antigen 3

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes."
      Gaugler B. , van den Eynde B. , van der Bruggen P. , Romero P. , Gaforio J.J. , De Plaen E. , Lethe B.G. , Brasseur F. , Boon T.
      J. Exp. Med.179:921-930(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];MUTAGENESIS
      tissue: Blood.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Skin.
    3. 3.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Testis.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The DNA sequence of the human X chromosome."
      Ross M.T. , Grafham D.V. , Coffey A.J. , Scherer S. , McLay K. , Muzny D. , Platzer M. , Howell G.R. , Burrows C. , Bird C.P. , Frankish A. , Lovell F.L. , Howe K.L. , Ashurst J.L. , Fulton R.S. , Sudbrak R. , Wen G. , Jones M.C. , more...
      Nature434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Bone marrow.
      tissue: Lung.
      tissue: Prostate.
      tissue: Skin.
    8. 8.
      "MAGE-A, mMage-b, and MAGE-C proteins form complexes with KAP1 and suppress p53-dependent apoptosis in MAGE-positive cell lines."
      Yang B. , O'Herrin S.M. , Wu J. , Reagan-Shaw S. , Ma Y. , Bhat K.M. , Gravekamp C. , Setaluri V. , Peters N. , Hoffmann F.M. , Peng H. , Ivanov A.V. , Simpson A.J. , Longley B.J.
      Cancer Res.67:9954-9962(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TRIM28
    9. 9.
      "MAGE-RING protein complexes comprise a family of E3 ubiquitin ligases."
      Doyle J.M. , Gao J. , Wang J. , Yang M. , Potts P.R.
      Mol. Cell39:963-974(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH TRIM28
    10. 10.
      "Human class I histocompatibility antigen (HLA-A complex with a nonameric peptide from melanoma-associated antigen 3 (residues 271-279)."
      Orth P. , Alings C. , Saenger W. , Ziegler A.
      Submitted (2009-02) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 271-279 IN COMPLEX WITH HLA CLASS I HISTOCOMPATIBILITY COMPLEX
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