Protein name:
Mastermind-like protein 2 (Mam-2) ;
Alternative:
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Interacts through its N-terminal region with the ankyrin repeat region of the Notch proteins NOTCH1, NOTCH2, NOTCH3 and NOTCH4. Forms a DNA-binding complex with Notch proteins and RBPSUH/RBP-J kappa.
Function:
Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Potentiates activation by NOTCH3 and NOTCH4 more efficiently than MAML1 or MAML3.
Subcellular Location:
Nucleus speckle
Nuclear, in a punctate manner.
Protein Attributes:
50:
MGDTAPPQAP | TGGLGGAPGA | GLLGGGSVTP | RVHSAIVERL | RARIAVCRQH |
100:
HLSCEGRYER | GRAESSDRER | ESTLQLLSLV | QHGQGARKAG | KHTKATASTA |
150:
TATAPPPAPA | APPTASQTAA | PAAPAPPPDY | HHHHQQHLRS | SSSSGGSGGI |
200:
DGEQQQQPPA | STPGDQRNSA | LIALQGSLKR | KQIVNLSPAN | SKRPNGFVDN |
250:
SFLDIKRIRV | GENLAAGPGG | LPVNNGQSQM | MSGTLPMSQV | PLRKTAALPP |
300:
PPTHSPGNGL | FNMGLKEVKK | EPGETLSCSK | HVDGQVTQEN | IFSNRYGDDP |
350:
GEQLMDPELQ | ELFNELTNIS | VPPMSDLELE | NMINATIKQD | DPFNIDLGQQ |
400:
SQRSTPRPSL | PLEKTVIKSE | YSPGLTQGPS | GSPQLRPSSA | GPAFSMASSG |
450:
LSASSPIPSV | PQSQAQPPPA | TGAARALPSW | QEVSHAQQLK | QIAANRQQHV |
500:
RMHQQQQQHQ | PTSWPALPSS | AGPSPGPFGQ | EKIPSPSFGQ | QPFSPQSTPM |
550:
PGVTGGSNQS | KVMANYLFKA | SPSAQGGPLD | VLLQPKPQDL | SRSFLNNPHP |
600:
AMEPRHGSTK | PLFHFNSDQA | NQQMPSVLPS | QSKPSLLHYT | QQQPQQSSIT |
650:
VQPQQQQQQP | QQQQQPQQQQ | QPQPQQQQQQ | QPQAQQPAAQ | PTQPLSNQPL |
700:
LRAPLPLQQK | ILLQKIQNQP | ITGLGYQVSQ | QHRQDQHSVV | GQNAGPSPSP |
750:
NPCSNPNTGS | GYMNSQQSLL | NQQLMGKKQT | LQRQIMEQKQ | QLLLQQQMLA |
800:
DAEKIAPQDQ | INRHLTRPPP | DYKDQRRNVG | NMQPTAQYSG | GSSTVSLNSN |
850:
QALANPVSTH | TILTPNSSLM | STSHGTRMPS | LPTAVQNIGI | YGNLPCSQPS |
900:
TYSVTSGMNQ | LTQPRNPNQL | IANQNNPLMP | RPPTLGPSNN | NNNNVATFGA |
950:
GSVGNSQQLR | PNLTHSMASM | PAQRTSNVMI | TSNTATPNWA | SQEATAKQQE |
1000:
ALKSAGVRFP | TGTTTAYAPN | QSLQQAVGSQ | QFSQRAVAPS | NQLTPAVQMR |
1050:
PMNQMSQTLN | GQNMGPLRSL | NLRPNQLSTQ | LLPTMNQAGT | GLSQSRTVSQ |
1100:
PPSLAAGGFP | SPNQSSRAFQ | GTDHGNDLAF | DFLNQQTDNM | GPALNSDADF |
1128:
IDSLLKTEPG | NDDWMKDINL | DEILGNNS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
ELISA Kit for Bovine Mam-2
ELISA Kit for Bovine Mam-2
CLIA Kit for Bovine Mam-2
CLIA Kit for Bovine Mam-2
Polyclonal Antibody for Bovine Mam-2
Polyclonal Antibody for Bovine Mam-2
Monoclonal Antibody for Bovine Mam-2
Monoclonal Antibody for Bovine Mam-2
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Precision
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Hereford .
tissue :
Fetal muscle .