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Index > Protein center > MAP6(Gene name) > Human
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  • MAP6 (Gene name),
  • Microtubule-associated protein 6 (Protein name ),  MAP6_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    MAP6(KIAA1878);
    Protein name:
    Microtubule-associated protein 6(MAP-6);
    Alternative:
    Stable tubule-only polypeptide(STOP);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with calmodulin (via C-terminus); the interaction is dependent on Ca(2+).
    Function:
    Involved in microtubule stabilization in many cell types, including neuronal cells. Specifically has microtubule cold stabilizing activity.
    Subcellular Location:
    Cytoplasm cytoskeleton Golgi apparatus Colocalizes with neurofilament (NF)-rich inclusions in spinal chord and brain neurons of patients with amyotrophic lateral sclerosis.
    Protein Attributes:
    Sequence length:
    813
    Sequence:
    50:
    MAWPCITRAC | CIARFWNQLD | KADIAVPLVF | TKYSEATEHP | GAPPQPPPPQ | 
    100:
    QQAQPALAPP | SARAVAIETQ | PAQGELDAVA | RATGPAPGPT | GEREPAAGPG | 
    150:
    RSGPGPGLGS | GSTSGPADSV | MRQDYRAWKV | QRPEPSCRPR | SEYQPSDAPF | 
    200:
    ERETQYQKDF | RAWPLPRRGD | HPWIPKPVQI | SAASQASAPI | LGAPKRRPQS | 
    250:
    QERWPVQAAA | EAREQEAAPG | GAGGLAAGKA | SGADERDTRR | KAGPAWIVRR | 
    300:
    AEGLGHEQTP | LPAAQAQVQA | TGPEAGRGRA | AADALNRQIR | EEVASAVSSS | 
    350:
    YRNEFRAWTD | IKPVKPIKAK | PQYKPPDDKM | VHETSYSAQF | KGEASKPTTA | 
    400:
    DNKVIDRRRI | RSLYSEPFKE | PPKVEKPSVQ | SSKPKKTSAS | HKPTRKAKDK | 
    450:
    QAVSGQAAKK | KSAEGPSTTK | PDDKEQSKEM | NNKLAEAKES | LAQPVSDSSK | 
    500:
    TQGPVATEPD | KDQGSVVPGL | LKGQGPMVQE | PLKKQGSVVP | GPPKDLGPMI | 
    550:
    PLPVKDQDHT | VPEPLKNESP | VISAPVKDQG | PSVPVPPKNQ | SPMVPAKVKD | 
    600:
    QGSVVPESLK | DQGPRIPEPV | KNQAPMVPAP | VKDEGPMVSA | SVKDQGPMVS | 
    650:
    APVKDQGPIV | PAPVKGEGPI | VPAPVKDEGP | MVSAPIKDQD | PMVPEHPKDE | 
    700:
    SAMATAPIKN | QGSMVSEPVK | NQGLVVSGPV | KDQDVVVPEH | AKVHDSAVVA | 
    750:
    PVKNQGPVVP | ESVKNQDPIL | PVLVKDQGPT | VLQPPKNQGR | IVPEPLKNQV | 
    800:
    PIVPVPLKDQ | DPLVPVPAKD | QGPAVPEPLK | TQGPRDPQLP | TVSPLPRVMI | 
    813:
    PTAPHTEYIE | SSP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    String:
    KEGG:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human MAP-6
    ELISA Kit for Human MAP-6
    ELISA Kit for Human MAP-6
    ELISA Kit for Human MAP-6
    CLIA Kit for Human MAP-6
    CLIA Kit for Human MAP-6
    CLIA Kit for Human MAP-6
    CLIA Kit for Human MAP-6
    Polyclonal Antibody for Human MAP-6
    Polyclonal Antibody for Human MAP-6
    Polyclonal Antibody for Human MAP-6
    Polyclonal Antibody for Human MAP-6
    Monoclonal Antibody for Human MAP-6
    Monoclonal Antibody for Human MAP-6
    Monoclonal Antibody for Human MAP-6
    Monoclonal Antibody for Human MAP-6
    Protein for Human MAP-6
    Protein for Human MAP-6
    Protein for Human MAP-6
    Protein for Human MAP-6

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      tissue: Brain.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3);VARIANT MET-247
      tissue: PNS.
    4. 4.
      "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T. , Nakayama M. , Nakajima D. , Kikuno R. , Ohara O.
      DNA Res.8:85-95(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 91-813 (ISOFORM 1)
      tissue: Brain.
    5. 5.
      "Stable tubule only polypeptides (STOP) proteins co-aggregate with spheroid neurofilaments in amyotrophic lateral sclerosis."
      Letournel F. , Bocquet A. , Dubas F. , Barthelaix A. , Eyer J.
      J. Neuropathol. Exp. Neurol.62:1211-1219(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    6. 6.
      "Genetic and expression analyses of the STOP (MAP6) gene in schizophrenia."
      Shimizu H. , Iwayama Y. , Yamada K. , Toyota T. , Minabe Y. , Nakamura K. , Nakajima M. , Hattori E. , Mori N. , Osumi N. , Yoshikawa T.
      Schizophr. Res.84:244-252(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    7. 7.
      "The FTLD risk factor TMEM106B and MAP6 control dendritic trafficking of lysosomes."
      Schwenk B.M. , Lang C.M. , Hogl S. , Tahirovic S. , Orozco D. , Rentzsch K. , Lichtenthaler S.F. , Hoogenraad C.C. , Capell A. , Haass C. , Edbauer D.
      EMBO J.33:450-467(2014) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH TMEM106B
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