Map6 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comMap6 ELISA Kit for Rat(Rattus norvegicus)

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Map6 (Gene name),

Microtubule-associated protein 6 (Protein name ), MAP6_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Map6(Mtap6);

Protein name:

Microtubule-associated protein 6(MAP-6);

Alternative:

Stable tubule-only polypeptide(STOP);145-kDa STOP(STOP145);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with calmodulin (via C-terminus); the interaction is dependent on Ca(2+).

Function:

Involved in microtubule stabilization in many cell types, including neuronal cells. Specifically has microtubule cold stabilizing activity.

Subcellular Location:

Cytoplasm cytoskeleton Golgi apparatus Isoform 1 and isoform 2 associate with axonal microtubules in neuronal cells. Preferentially is concentrated on a portion of the microtubule polymer in which tubulin is modified by detyrosination and acetylation and is also resistant to depolymerization induced by both nocodazole and cold.

Protein Attributes:

Sequence length:

952

Sequence:

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950:

952:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

10116.ENSRNOP00000032018

Pfam:

PF05217

UniGene:

Rn.37490

String:

Q63560

KEGG:

rno:29457

Uniprot:

Q63560

FOR

ELISA Kit for Rat MAP-6

CLIA Kit for Rat MAP-6

Polyclonal Antibody for Rat MAP-6

Monoclonal Antibody for Rat MAP-6

Protein for Rat MAP-6

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning, expression, and properties of the microtubule-stabilizing protein STOP."
Bosc C. , Cronk J.D. , Pirollet F. , Watterson D.M. , Haiech J. , Job D. , Margolis R.L.
Proc. Natl. Acad. Sci. U.S.A.93:2125-2130(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PARTIAL PROTEIN SEQUENCE;FUNCTION;INTERACTION WITH CALMODULIN;SUBCELLULAR LOCATION
strain: Sprague-Dawley.
tissue: Brain.
2.

"STOP proteins are responsible for the high degree of microtubule stabilization observed in neuronal cells."
Guillaud L. , Bosc C. , Fourest-Lieuvin A. , Denarier E. , Pirollet F. , Lafanechere L. , Job D.
J. Cell Biol.142:167-179(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
strain: Sprague-Dawley.
tissue: Brain.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-613 (ISOFORM 2)
tissue: Testis.
4.

"Purification and assay of a 145-kDa protein (STOP145) with microtubule-stabilizing and motility behavior."
Margolis R.L. , Rauch C.T. , Job D.
Proc. Natl. Acad. Sci. U.S.A.83:639-643(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
5.

"Identification of novel bifunctional calmodulin-binding and microtubule-stabilizing motifs in STOP proteins."
Bosc C. , Frank R. , Denarier E. , Ronjat M. , Schweitzer A. , Wehland J. , Job D.
J. Biol. Chem.276:30904-30913(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CALMODULIN
6.

"STOP (stable-tubule-only-polypeptide) is preferentially associated with the stable domain of axonal microtubules."
Slaughter T. , Black M.M.
J. Neurocytol.32:399-413(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION

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