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Index > Protein center > Mybbp1a(Gene name) > Rat
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  • Mybbp1a (Gene name),
  • Myb-binding protein 1A (Protein name ),  MBB1A_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Mybbp1a;
    Protein name:
    Myb-binding protein 1A;
    Alternative:
    PAR-interacting protein(PIP);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Binds to and represses JUN and MYB via the leucine zipper regions present in these proteins. Also binds to and represses PPARGC1A: this interaction is abrogated when PPARGC1A is phosphorylated by MAPK1/ERK. Binds to and stimulates transcription by AHR. Binds to KPNA2. Component of the B-WICH complex, at least composed of SMARCA5/SNF2H, BAZ1B/WSTF, SF3B1, DEK, MYO1C, ERCC6, MYBBP1A and DDX21.
    Function:
    May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity).
    Subcellular Location:
    Nucleus nucleolus Cytoplasm Predominantly nucleolar. Also shuttles between the nucleus and cytoplasm. Nuclear import may be mediated by KPNA2, while export appears to depend partially on XPO1/CRM1.
    Protein Attributes:
    Sequence length:
    1344
    Sequence:
    50:
    MAEMKSPTKA | EPASPAEAPQ | GDRRSLLEHS | REFLDFFWDI | AKPDQETRLR | 
    100:
    ATEKLLEYLR | TRPSDSEMKY | ALKRLITGLG | VGREAARPCY | SLALAQLLQS | 
    150:
    FEDIQLCDIL | GQIQEKYNLQ | AMNKAMMRPT | LFANLFGVLA | LFQSGRLVKD | 
    200:
    KEALMKCVRL | LKILSHHYNH | LQGQPVKALV | DILSEVPESM | FQEILPKVLK | 
    250:
    GDMKVILSSP | KYLELFLLAR | QRVPAELESL | VGSVDLFSED | NIPSLVNILK | 
    300:
    VAANSVKKEQ | KLPDVALNLL | RLALQENKFE | RFWKEVLEEG | LLKKPSYTSS | 
    350:
    YMCFRLLGAS | LPLLSDEQLQ | LVMRGDLIRH | FGEHMVVSKS | QNPLRFIPEI | 
    400:
    SAYVGTFLEG | CQDDPKRQFT | VMVAFTAITN | QGLPVMPTFW | RVTRFLNTEA | 
    450:
    LQNYVTWLRD | MFLQPDLDSL | VDFSTANQKR | VQVASLNVPE | RTVFRLRKWI | 
    500:
    IHRLVSLVDH | LHLEKDEAVV | EQIARFCLFH | AFFKTKKATP | QIPETKQHFS | 
    550:
    FPLEDGNRGV | IVSAFFSLLQ | TLSVKFRQTP | DLAENGKPWT | YRLVQLADML | 
    600:
    LKHNRNVANV | TPLTAQQRQA | WDQMMSTLKE | LEAQSSETRA | IAFQHLLLLV | 
    650:
    GLHLFKSPAE | SCDVLGDIQT | CIKKSMEQNL | RRSRSRAKAS | QEPVWVEVMV | 
    700:
    EILLSLLAQP | SNLMRQVVRS | VFGHVCSHLT | PRGLQLILAV | LNPETNEDEE | 
    750:
    DNVVVTDTDE | KQLKHGEDAD | SDSEDSKNSE | SDVDSEDGEE | SEEEDRDKDV | 
    800:
    DPGFRQQLME | VLQAGNALGG | EEEEEEELGD | EAMMALDQNL | ASLFAEQKMR | 
    850:
    IQARHEEKNK | LQKEKQLRRD | FQIRALDLIE | VLVTKQPEHP | LILELLEPLL | 
    900:
    NIIQRSMRSR | GSTKQEQDLL | HKTARIFMHH | LCRARHYCHE | VEPGAEALHA | 
    950:
    QVERLVQQAG | NQADASVALY | YFNASLYLLR | VLKGNTTKRY | QDGQKLEGAD | 
    1000:
    IKSEPKDSEV | QTTSCLDLDF | VTRVYSASLE | SLLTKRNSPL | TIPMFLDLFS | 
    1050:
    RYPVICKNLL | PIVVQHVAGS | SRPRHQAQAC | LLLQKALSAR | ELRVCFEDPE | 
    1100:
    WEQLISQVLG | KTTQTLQTLG | EAQSKGEHQR | ELSILELLNT | VFRIVNHEKL | 
    1150:
    SVDLTAFLGM | LQGKQQKLQQ | NLQQGNHSSG | SSRLYDLYWQ | AMNLLGVQRP | 
    1200:
    KSEKKNVKDI | PSDSQSPIST | KRKKKGFLPE | TKKRKKLKSE | GTTSEKKAAS | 
    1250:
    QQDAVTEGAM | PAATGKDQPP | STGKKRRKRV | KANTPSQVNG | VTVAKSPAPN | 
    1300:
    NPTLSPSTPP | AKTPKVQKKK | EKLSQVNGST | PVSPVEPESK | KHQKALSTKE | 
    1344:
    VKRRSSQSAL | PKKRARLSLV | SRSPSLLQSG | IRKRRVARRR | VQTP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Myb-binding protein 1A
    ELISA Kit for Rat Myb-binding protein 1A
    ELISA Kit for Rat Myb-binding protein 1A
    CLIA Kit for Rat Myb-binding protein 1A
    CLIA Kit for Rat Myb-binding protein 1A
    CLIA Kit for Rat Myb-binding protein 1A
    Polyclonal Antibody for Rat Myb-binding protein 1A
    Polyclonal Antibody for Rat Myb-binding protein 1A
    Polyclonal Antibody for Rat Myb-binding protein 1A
    Monoclonal Antibody for Rat Myb-binding protein 1A
    Monoclonal Antibody for Rat Myb-binding protein 1A
    Monoclonal Antibody for Rat Myb-binding protein 1A
    Protein for Rat Myb-binding protein 1A
    Protein for Rat Myb-binding protein 1A
    Protein for Rat Myb-binding protein 1A

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    References
    1. 1.
      "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Gibbs R.A. , Weinstock G.M. , Metzker M.L. , Muzny D.M. , Sodergren E.J. , Scherer S. , Scott G. , Steffen D. , Worley K.C. , Burch P.E. , Okwuonu G. , Hines S. , Lewis L. , Deramo C. , Delgado O. , Dugan-Rocha S. , Miner G. , Morgan M. , more...
      Nature428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
    2. 2.
      "Isolation of PIP, a 160 kDa nucleolar protein that interacts with the activation domain of PAR transcription factors."
      Comte P.A. , Ossipow V. , Schibler U.
      Submitted (1997-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 68-1344
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