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Index > Protein center > Mbl2(Gene name) > Mouse
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  • Mbl2 (Gene name),
  • Mannose-binding protein C (Protein name ),  MBL2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Mbl2;
    Protein name:
    Mannose-binding protein C(MBP-C);
    Alternative:
    RA-reactive factor P28A subunit(RARF/P28A);Mannan-binding protein;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Oligomeric complex of 3 or more homotrimers. Interacts with MASP1 and MASP2 (By similarity). Interacts with MEP1A and MEP1B and may inhibit their catalytic activity.
    Function:
    Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    244
    Sequence:
    50:
    MSIFTSFLLL | CVVTVVYAET | LTEGVQNSCP | VVTCSSPGLN | GFPGKDGRDG | 
    100:
    AKGEKGEPGQ | GLRGLQGPPG | KVGPTGPPGN | PGLKGAVGPK | GDRGDRAEFD | 
    150:
    TSEIDSEIAA | LRSELRALRN | WVLFSLSEKV | GKKYFVSSVK | KMSLDRVKAL | 
    200:
    CSEFQGSVAT | PRNAEENSAI | QKVAKDIAYL | GITDVRVEGS | FEDLTGNRVR | 
    244:
    YTNWNDGEPN | NTGDGEDCVV | ILGNGKWNDV | PCSDSFLAIC | EFSD
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    KEGG:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse MBP-C
    Cat.:
    E1480h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse MBP-C
    Cat.:
    E1480m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse MBP-C
    Cat.:
    E1480p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse MBP-C
    Cat.:
    E1480r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse MBP-C
    Cat.:
    U1480r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse MBP-C
    Cat.:
    U1480p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse MBP-C
    Cat.:
    U1480m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse MBP-C
    Cat.:
    U1480h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Mouse MBP-C
    Cat.:
    P1480Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse MBP-C
    Cat.:
    P1480Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse MBP-C
    Cat.:
    P1480Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse MBP-C
    Monoclonal Antibody for Mouse MBP-C
    Monoclonal Antibody for Mouse MBP-C
    Monoclonal Antibody for Mouse MBP-C
    Monoclonal Antibody for Mouse MBP-C
    Protein for Mouse MBP-C
    Protein for Mouse MBP-C
    Protein for Mouse MBP-C
    Protein for Mouse MBP-C

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular characterization of the mouse mannose-binding proteins. The mannose-binding protein A but not C is an acute phase reactant."
      Sastry K. , Zahedi K. , Lelias J.M. , Whitehead A.S. , Ezekowitz R.A.
      J. Immunol.147:692-697(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
      strain: CBA/J.
      tissue: Liver.
    2. 2.
      "Characterization of murine mannose-binding protein genes Mbl1 and Mbl2 reveals features common to other collectin genes."
      Sastry R. , Wang J.S. , Brown D.C. , Ezekowitz R.A. , Tauber A.I. , Sastry K.N.
      Mamm. Genome6:103-110(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
      strain: BALB/c.
    3. 3.
      Kuge S. , Ihara S. , Watanabe E. , Watanabe M. , Takishima K. , Suga T. , Mamaiya G. , Kawakami M.
      Submitted (1992-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Liver.
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