Protein name:
Mannose-binding protein C (MBP-C) ;
Alternative:
Mannose-binding lectin (MBL) ;27 kDa mannan-binding protein monomeric subunit (pMBP-27) ;
Organism:
Pig (Sus scrofa).
General Annotation
Sub Unit:
Interacts with MASP1 and MASP2. Interacts with MEP1A and MEP1B and may inhibit their catalytic activity (By similarity). Forms oligomeric complexes of 2 or 3 homotrimers.
Function:
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. According to some authors, it only binds mannose (PubMed:8602463).
Subcellular Location:
Secreted
Protein Attributes:
50:
MSLFPSLHLL | LLIVMTASHT | ETENCEDIQN | TCLVISCDSP | GINGLPGKDG |
100:
LDGAKGEKGE | PGQGLIGLQG | LPGMVGPQGS | PGIPGLPGLK | GQKGDSGIDP |
150:
GNSLANLRSE | LDNIKKWLIF | AQGKQVGKKL | YLTNGKKMSF | NGVKALCAQF |
200:
QASVATPTNS | RENQAIQELA | GTEAFLGITD | EYTEGQFVDL | TGKRVRYQNW |
240:
NDGEPNNADS | AEHCVEILKD | GKWNDIFCSS | QLSAVCEFPA |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Pig
Rat
Polyclonal Antibody for Pig MBP-C
Polyclonal Antibody for Pig MBP-C
Polyclonal Antibody for Pig MBP-C
Polyclonal Antibody for Pig MBP-C
Monoclonal Antibody for Pig MBP-C
Monoclonal Antibody for Pig MBP-C
Monoclonal Antibody for Pig MBP-C
Monoclonal Antibody for Pig MBP-C
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 94-161 AND 195-219;FUNCTION;TISSUE SPECIFICITY
tissue :
Liver .
tissue :
Serum .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-28;TISSUE SPECIFICITY
strain :
Landrace .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 19-44;FUNCTION;SUBUNIT
tissue :
Serum .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;TISSUE SPECIFICITY