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Index > Protein center > MBL2(Gene name) > Pig
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  • MBL2 (Gene name),
  • Mannose-binding protein C (Protein name ),  MBL2_PIG from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    MBL2;
    Protein name:
    Mannose-binding protein C(MBP-C);
    Alternative:
    Mannose-binding lectin(MBL);27 kDa mannan-binding protein monomeric subunit(pMBP-27);
    Organism:
    Pig (Sus scrofa). 
    General Annotation
    Sub Unit:
    Interacts with MASP1 and MASP2. Interacts with MEP1A and MEP1B and may inhibit their catalytic activity (By similarity). Forms oligomeric complexes of 2 or 3 homotrimers.
    Function:
    Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. According to some authors, it only binds mannose (PubMed:8602463).
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    240
    Sequence:
    50:
    MSLFPSLHLL | LLIVMTASHT | ETENCEDIQN | TCLVISCDSP | GINGLPGKDG | 
    100:
    LDGAKGEKGE | PGQGLIGLQG | LPGMVGPQGS | PGIPGLPGLK | GQKGDSGIDP | 
    150:
    GNSLANLRSE | LDNIKKWLIF | AQGKQVGKKL | YLTNGKKMSF | NGVKALCAQF | 
    200:
    QASVATPTNS | RENQAIQELA | GTEAFLGITD | EYTEGQFVDL | TGKRVRYQNW | 
    240:
    NDGEPNNADS | AEHCVEILKD | GKWNDIFCSS | QLSAVCEFPA | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Pig MBP-C
    Cat.:
    E1480h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Pig MBP-C
    Cat.:
    E1480m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Pig MBP-C
    Cat.:
    E1480p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Pig MBP-C
    Cat.:
    E1480r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Pig MBP-C
    Cat.:
    U1480r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Pig MBP-C
    Cat.:
    U1480p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig MBP-C
    Cat.:
    U1480m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Pig MBP-C
    Cat.:
    U1480h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Pig MBP-C
    Cat.:
    P1480Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig MBP-C
    Cat.:
    P1480Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig MBP-C
    Cat.:
    P1480Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig MBP-C
    Monoclonal Antibody for Pig MBP-C
    Monoclonal Antibody for Pig MBP-C
    Monoclonal Antibody for Pig MBP-C
    Monoclonal Antibody for Pig MBP-C
    Protein for Pig MBP-C
    Protein for Pig MBP-C
    Protein for Pig MBP-C
    Protein for Pig MBP-C

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Isolation, cloning and functional characterization of porcine mannose-binding lectin."
      Agah A. , Montalto M.C. , Young K. , Stahl G.L.
      Immunology102:338-343(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 94-161 AND 195-219;FUNCTION;TISSUE SPECIFICITY
      tissue: Liver.
      tissue: Serum.
    2. 2.
      "Gene polymorphisms associated with reduced hepatic expression of porcine mannan-binding lectin C."
      Lillie B.N. , Keirstead N.D. , Squires E.J. , Hayes M.A.
      Dev. Comp. Immunol.31:830-846(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-28;TISSUE SPECIFICITY
      strain: Landrace.
    3. 3.
      "Isolation and characterization of porcine mannan-binding proteins of different size and ultrastructure."
      Storgaard P. , Nielsen E.H. , Andersen O. , Skriver E. , Mortensen H. , Hojrup P. , Leslie G. , Holmskow U. , Svehag S.E.
      Scand. J. Immunol.43:289-296(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 19-44;FUNCTION;SUBUNIT
      tissue: Serum.
    4. 4.
      "Molecular genetic analysis of porcine mannose-binding lectin genes, MBL1 and MBL2, and their association with complement activity."
      Phatsara C. , Jennen D.G. , Ponsuksili S. , Murani E. , Tesfaye D. , Schellander K. , Wimmers K.
      Int. J. Immunogenet.34:55-63(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
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