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Index > Protein center > Mbl2(Gene name) > Rat
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  • Mbl2 (Gene name),
  • Mannose-binding protein C (Protein name ),  MBL2_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Mbl2;
    Protein name:
    Mannose-binding protein C(MBP-C);
    Alternative:
    Ra-reactive factor polysaccharide-binding component p28A(RaRF p28A);Mannan-binding protein;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Oligomeric complex of 3 or more homotrimers. Interacts with MASP1 and MASP2 (By similarity). Interacts with MEP1A and MEP1B and may inhibit their catalytic activity.
    Function:
    Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    244
    Sequence:
    50:
    MSLFTSFLLL | CVLTAVYAET | LTEGAQSSCP | VIACSSPGLN | GFPGKDGHDG | 
    100:
    AKGEKGEPGQ | GLRGLQGPPG | KVGPAGPPGN | PGSKGATGPK | GDRGESVEFD | 
    150:
    TTNIDLEIAA | LRSELRAMRK | WVLLSMSENV | GKKYFMSSVR | RMPLNRAKAL | 
    200:
    CSELQGTVAT | PRNAEENRAI | QNVAKDVAFL | GITDQRTENV | FEDLTGNRVR | 
    244:
    YTNWNEGEPN | NVGSGENCVV | LLTNGKWNDV | PCSDSFLVVC | EFSD
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    SMR:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Rat MBP-C
    Cat.:
    E1480h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Rat MBP-C
    Cat.:
    E1480m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat MBP-C
    Cat.:
    E1480p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat MBP-C
    Cat.:
    E1480r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat MBP-C
    Cat.:
    U1480r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat MBP-C
    Cat.:
    U1480p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat MBP-C
    Cat.:
    U1480m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat MBP-C
    Cat.:
    U1480h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Rat MBP-C
    Cat.:
    P1480Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat MBP-C
    Cat.:
    P1480Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat MBP-C
    Cat.:
    P1480Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat MBP-C
    Monoclonal Antibody for Rat MBP-C
    Monoclonal Antibody for Rat MBP-C
    Monoclonal Antibody for Rat MBP-C
    Monoclonal Antibody for Rat MBP-C
    Protein for Rat MBP-C
    Protein for Rat MBP-C
    Protein for Rat MBP-C
    Protein for Rat MBP-C

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Characterization of rat liver mannan-binding protein gene."
      Wada M. , Itoh N. , Ohta M. , Kawasaki T.
      J. Biochem.111:66-73(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Liver.
    2. 2.
      "Mannose-binding proteins isolated from rat liver contain carbohydrate-recognition domains linked to collagenous tails. Complete primary structures and homology with pulmonary surfactant apoprotein."
      Drickamer K. , Dordal M.S. , Reynolds L.
      J. Biol. Chem.261:6878-6887(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
      tissue: Liver.
    3. 3.
      "Primary structure of rat liver mannan-binding protein deduced from its cDNA sequence."
      Oka S. , Itoh N. , Kawasaki T. , Yamashina I.
      J. Biochem.101:135-144(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Wistar.
      tissue: Liver.
    4. 4.
      "Impaired secretion of rat mannose-binding protein resulting from mutations in the collagen-like domain."
      Heise C.T. , Nicholls J.R. , Leamy C.E. , Wallis R.
      J. Immunol.165:1403-1409(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    5. 5.
      "Structural analysis of monosaccharide recognition by rat liver mannose-binding protein."
      Ng K.K.-S. , Drickamer K. , Weis W.I.
      J. Biol. Chem.271:663-674(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) OF 133-244
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