Protein name:
Mannose-binding protein C (MBP-C) ;
Alternative:
Ra-reactive factor polysaccharide-binding component p28A (RaRF p28A) ;Mannan-binding protein ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Oligomeric complex of 3 or more homotrimers. Interacts with MASP1 and MASP2 (By similarity). Interacts with MEP1A and MEP1B and may inhibit their catalytic activity.
Function:
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages.
Subcellular Location:
Secreted
Protein Attributes:
50:
MSLFTSFLLL | CVLTAVYAET | LTEGAQSSCP | VIACSSPGLN | GFPGKDGHDG |
100:
AKGEKGEPGQ | GLRGLQGPPG | KVGPAGPPGN | PGSKGATGPK | GDRGESVEFD |
150:
TTNIDLEIAA | LRSELRAMRK | WVLLSMSENV | GKKYFMSSVR | RMPLNRAKAL |
200:
CSELQGTVAT | PRNAEENRAI | QNVAKDVAFL | GITDQRTENV | FEDLTGNRVR |
244:
YTNWNEGEPN | NVGSGENCVV | LLTNGKWNDV | PCSDSFLVVC | EFSD
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Pig
Rat
Polyclonal Antibody for Rat MBP-C
Polyclonal Antibody for Rat MBP-C
Polyclonal Antibody for Rat MBP-C
Polyclonal Antibody for Rat MBP-C
Monoclonal Antibody for Rat MBP-C
Monoclonal Antibody for Rat MBP-C
Monoclonal Antibody for Rat MBP-C
Monoclonal Antibody for Rat MBP-C
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Liver .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
tissue :
Liver .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Wistar .
tissue :
Liver .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) OF 133-244