Mcpt4 ELISA Kit for Mouse(Mus musculus) | EIAab.comMcpt4 ELISA Kit for Mouse(Mus musculus)

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Mcpt4 (Gene name),

Mast cell protease 4 (Protein name ), MCPT4_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Mcpt4;

Protein name:

Mast cell protease 4(mMCP-4);

Alternative:

Myonase;MSMCP;Serosal mast cell protease;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Monomer.

Function:

Has chymotrypsin-like activity. Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. Preferentially hydrolyzes the 'Tyr-4-|-Ile-5' bond of angiotensin I and the 'Phe-20-|-Ala-21' bond of amyloid beta-protein, and is less active towards the 'Phe-8-|-His-9' bond of angiotensin I and the 'Phe-4-|-Ala-5' and 'Tyr-10-|-Glu-11' bonds of amyloid beta-protein. Involved in thrombin regulation and fibronectin processing.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

246

Sequence:

50:

100:

150:

200:

246:

DSGGPLLCAG | VAHGIVSYGR | GDAKPPAVFT | RISSYVPWIN | RVIKGE

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P21812

UniGene:

Mm.439684

Pfam:

PF00089

SMR:

P21812

KEGG:

mmu:17227

Uniprot:

P21812

FOR

ELISA Kit for Mouse mMCP-4

CLIA Kit for Mouse mMCP-4

Polyclonal Antibody for Mouse mMCP-4

Monoclonal Antibody for Mouse mMCP-4

Protein for Mouse mMCP-4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning of the cDNA and gene for mouse mast cell protease 4. Demonstration of its late transcription in mast cell subclasses and analysis of its homology to subclass-specific neutral proteases of the mouse and rat."
Serafin W.E. , Sullivan T.P. , Conder G.A. , Ebrahimi A. , Marcham P. , Johnson S.S. , Austen K.F. , Reynolds D.S.
J. Biol. Chem.266:1934-1941(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
strain: BALB/c.
2.

"Independent influence of strain difference and mi transcription factor on the expression of mouse mast cell chymases."
Ge Y. , Jippo T. , Lee Y.-M. , Adachi S. , Kitamura Y.
Am. J. Pathol.158:281-292(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: C57BL/6.
3.

"Cloning and structural analysis of MMCP-1, MMCP-4 and MMCP-5, three mouse mast cell-specific serine proteases."
Huang R. , Blom T. , Hellman L.
Eur. J. Immunol.21:1611-1621(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 7-246
strain: Leaden X A1.
tissue: Mastocytoma.
4.

"Purification and characterization of myonase from X-chromosome linked muscular dystrophic mouse skeletal muscle."
Hori S. , Ohtani S. , Hori C. , Nokihara K.
J. Biochem.123:650-658(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 7-246;PROTEIN SEQUENCE OF 21-66; 76-84; 86-93; 96-106; 126-143; 146-155; 178-180; 197-207 AND 231-238;FUNCTION;SUBUNIT;TISSUE SPECIFICITY;MASS SPECTROMETRY
tissue: Skeletal muscle.
5.

"Different mouse mast cell populations express various combinations of at least six distinct mast cell serine proteases."
Reynolds D.S. , Stevens R.L. , Lane W.S. , Carr M.H. , Austen K.F. , Serafin W.E.
Proc. Natl. Acad. Sci. U.S.A.87:3230-3234(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 21-43
6.

"Biochemical and immunological characterization of multiple glycoforms of mouse mast cell protease 1: comparison with an isolated murine serosal mast cell protease (MMCP-4)."
Newlands G.F.J. , Knox D.P. , Pirie-Shepherd S.R. , Miller H.R.P.
Biochem. J.294:127-135(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 21-40
7.

"The chymase, mouse mast cell protease 4, constitutes the major chymotrypsin-like activity in peritoneum and ear tissue. A role for mouse mast cell protease 4 in thrombin regulation and fibronectin turnover."
Tchougounova E. , Pejler G. , Abrink M.
J. Exp. Med.198:423-431(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE

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