Mdfi ELISA Kit for Mouse(Mus musculus) | EIAab.comMdfi ELISA Kit for Mouse(Mus musculus)

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Mdfi (Gene name),

MyoD family inhibitor (Protein name ), MDFI_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Mdfi;

Protein name:

MyoD family inhibitor;

Alternative:

Myogenic repressor I-mf;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

The C-terminus interacts with AXIN1 and LEF1.

Function:

Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis. Acts by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear localization signals. Can also interfere with the DNA-binding activity of Myod family members. Plays an important role in trophoblast and chondrogenic differentiation. Regulates the transcriptional activity of TCF7L1/TCF3 by interacting directly with TCF7L1/TCF3 and preventing it from binding DNA. Binds to the axin complex, resulting in an increase in the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways.

Subcellular Location:

Nucleus Cytoplasm

Protein Attributes:

Sequence length:

251

Sequence:

50:

100:

150:

200:

250:

251:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.329100

String:

P70331

KEGG:

mmu:17240

Uniprot:

P70331

FOR

ELISA Kit for Mouse MyoD family inhibitor

CLIA Kit for Mouse MyoD family inhibitor

Polyclonal Antibody for Mouse MyoD family inhibitor

Monoclonal Antibody for Mouse MyoD family inhibitor

Protein for Mouse MyoD family inhibitor

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"I-mf, a novel myogenic repressor, interacts with members of the MyoD family."
Chen C.-M.A. , Kraut N. , Groudine M. , Weintraub H.
Cell86:731-741(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS I-MFA; I-MFB AND I-MFC);FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
strain: NIH Swiss.
tissue: Embryo.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM I-MFA)
strain: 129.
strain: FVB/N.
tissue: Mammary gland.
3.

"Requirement of the mouse I-mfa gene for placental development and skeletal patterning."
Kraut N. , Snider L. , Chen C.-M.A. , Tapscott S.J. , Groudine M.
EMBO J.17:6276-6288(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
4.

"Inhibition of Tcf3 binding by I-mfa domain proteins."
Snider L. , Thirlwell H. , Miller J.R. , Moon R.T. , Groudine M. , Tapscott S.J.
Mol. Cell. Biol.21:1866-1873(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
5.

"I-mfa domain proteins interact with Axin and affect its regulation of the Wnt and c-Jun N-terminal kinase signaling pathways."
Kusano S. , Raab-Traub N.
Mol. Cell. Biol.22:6393-6405(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH AXIN1 AND LEF1

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