"Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells."
Chen C.-J. , Chin J.E. , Ueda K. , Clark D.P. , Pastan I. , Gottesman M.M. , Roninson I.B.
Cell47:381-389(1986) [PubMed] [Europe PMC] [Abstract]

"Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins."
Chen C.-J. , Clark D.P. , Ueda K. , Pastan I. , Gottesman M.M. , Roninson I.B.
J. Biol. Chem.265:506-514(1990) [PubMed] [Europe PMC] [Abstract]

"Multidrug-resistant human sarcoma cells with a mutant P-glycoprotein, altered phenotype, and resistance to cyclosporins."
Chen G. , Duran G.E. , Steger K.A. , Lacayo N.J. , Jaffrezou J.P. , Dumontet C. , Sikic B.I.
J. Biol. Chem.272:5974-5982(1997) [PubMed] [Europe PMC] [Abstract]

"Cloning of P-glycoprotein cDNA sequence from breast cancer MCF7 cell line."
Jiang Y. , Sun Q. , Xie Z. , Liu F. , Xu W. , Wang Y.
Submitted (2008-06) to the EMBL/GenBank/DDBJ databases

NIEHS SNPs program
Submitted (2005-01) to the EMBL/GenBank/DDBJ databases

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , Yamamoto J. , Saito K. , Kawai Y. , Isono Y. , Nakamura Y. , Nagahari K. , Murakami K. , Yasuda T. , Iwayanagi T. , Wagatsuma M. , Shiratori A. , Sudo H. , Hosoiri T. , Kaku Y. , Kodaira H. , Kondo H. , Sugawara M. , Takahashi M. , Kanda K. , Yokoi T. , Furuya T. , Kikkawa E. , Omura Y. , Abe K. , Kamihara K. , Katsuta N. , Sato K. , Tanikawa M. , Yamazaki M. , Ninomiya K. , Ishibashi T. , Yamashita H. , Murakawa K. , Fujimori K. , Tanai H. , Kimata M. , Watanabe M. , Hiraoka S. , Chiba Y. , Ishida S. , Ono Y. , Takiguchi S. , Watanabe S. , Yosida M. , Hotuta T. , Kusano J. , Kanehori K. , Takahashi-Fujii A. , Hara H. , Tanase T.-O. , Nomura Y. , Togiya S. , Komai F. , Hara R. , Takeuchi K. , Arita M. , Imose N. , Musashino K. , Yuuki H. , Oshima A. , Sasaki N. , Aotsuka S. , Yoshikawa Y. , Matsunawa H. , Ichihara T. , Shiohata N. , Sano S. , Moriya S. , Momiyama H. , Satoh N. , Takami S. , Terashima Y. , Suzuki O. , Nakagawa S. , Senoh A. , Mizoguchi H. , Goto Y. , Shimizu F. , Wakebe H. , Hishigaki H. , Watanabe T. , Sugiyama A. , Takemoto M. , Kawakami B. , Yamazaki M. , Watanabe K. , Kumagai A. , Itakura S. , Fukuzumi Y. , Fujimori Y. , Komiyama M. , Tashiro H. , Tanigami A. , Fujiwara T. , Ono T. , Yamada K. , Fujii Y. , Ozaki K. , Hirao M. , Ohmori Y. , Kawabata A. , Hikiji T. , Kobatake N. , Inagaki H. , Ikema Y. , Okamoto S. , Okitani R. , Kawakami T. , Noguchi S. , Itoh T. , Shigeta K. , Senba T. , Matsumura K. , Nakajima Y. , Mizuno T. , Morinaga M. , Sasaki M. , Togashi T. , Oyama M. , Hata H. , Watanabe M. , Komatsu T. , Mizushima-Sugano J. , Satoh T. , Shirai Y. , Takahashi Y. , Nakagawa K. , Okumura K. , Nagase T. , Nomura N. , Kikuchi H. , Masuho Y. , Yamashita R. , Nakai K. , Yada T. , Nakamura Y. , Ohara O. , Isogai T. , Sugano S. more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence of human chromosome 7."
Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Cordes M. , Du H. , Sun H. , Edwards J. , Bradshaw-Cordum H. , Ali J. , Andrews S. , Isak A. , Vanbrunt A. , Nguyen C. , Du F. , Lamar B. , Courtney L. , Kalicki J. , Ozersky P. , Bielicki L. , Scott K. , Holmes A. , Harkins R. , Harris A. , Strong C.M. , Hou S. , Tomlinson C. , Dauphin-Kohlberg S. , Kozlowicz-Reilly A. , Leonard S. , Rohlfing T. , Rock S.M. , Tin-Wollam A.-M. , Abbott A. , Minx P. , Maupin R. , Strowmatt C. , Latreille P. , Miller N. , Johnson D. , Murray J. , Woessner J.P. , Wendl M.C. , Yang S.-P. , Schultz B.R. , Wallis J.W. , Spieth J. , Bieri T.A. , Nelson J.O. , Berkowicz N. , Wohldmann P.E. , Cook L.L. , Hickenbotham M.T. , Eldred J. , Williams D. , Bedell J.A. , Mardis E.R. , Clifton S.W. , Chissoe S.L. , Marra M.A. , Raymond C. , Haugen E. , Gillett W. , Zhou Y. , James R. , Phelps K. , Iadanoto S. , Bubb K. , Simms E. , Levy R. , Clendenning J. , Kaul R. , Kent W.J. , Furey T.S. , Baertsch R.A. , Brent M.R. , Keibler E. , Flicek P. , Bork P. , Suyama M. , Bailey J.A. , Portnoy M.E. , Torrents D. , Chinwalla A.T. , Gish W.R. , Eddy S.R. , McPherson J.D. , Olson M.V. , Eichler E.E. , Green E.D. , Waterston R.H. , Wilson R.K. more...
Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]

"mdr1/P-glycoprotein gene segments analyzed from various human leukemic cell lines exhibiting different multidrug resistance profiles."
Gekeler V. , Weger S. , Probst H.
Biochem. Biophys. Res. Commun.169:796-802(1990) [PubMed] [Europe PMC] [Abstract]

"P-glycoprotein gene (MDR1) cDNA from human adrenal: normal P-glycoprotein carries Gly185 with an altered pattern of multidrug resistance."
Kioka N. , Tsubota J. , Kakehi Y. , Komano T. , Gottesman M.M. , Pastan I. , Ueda K.
Biochem. Biophys. Res. Commun.162:224-231(1989) [PubMed] [Europe PMC] [Abstract]

"ABC drug transporters: hereditary polymorphisms and pharmacological impact in MDR1, MRP1 and MRP2."
Kerb R. , Hoffmeyer S. , Brinkmann U.
Pharmacogenomics2:51-64(2001) [PubMed] [Europe PMC] [Abstract]

"Cytoplasmic domains of the transporter associated with antigen processing and P-glycoprotein interact with subunits of the proteasome."
Begley G.S. , Horvath A.R. , Taylor J.C. , Higgins C.F.
Mol. Immunol.42:137-141(2005) [PubMed] [Europe PMC] [Abstract]

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"Protein phosphatase complex PP5/PPP2R3C dephosphorylates P-glycoprotein/ABCB1 and down-regulates the expression and function."
Katayama K. , Yamaguchi M. , Noguchi K. , Sugimoto Y.
Cancer Lett.345:124-131(2014) [PubMed] [Europe PMC] [Abstract]

"An altered pattern of cross-resistance in multidrug-resistant human cells results from spontaneous mutations in the mdr1 (P-glycoprotein) gene."
Choi K.H. , Chen C.-J. , Kriegler M. , Roninson I.B.
Cell53:519-529(1988) [PubMed] [Europe PMC] [Abstract]

"Genetic polymorphism in MDR-1: a tool for examining allelic expression in normal cells, unselected and drug-selected cell lines, and human tumors."
Mickley L.A. , Lee J.-S. , Weng Z. , Zhan Z. , Alvarez M. , Wilson W. , Bates S.E. , Fojo T.
Blood91:1749-1756(1998) [PubMed] [Europe PMC] [Abstract]

"A new polymorphism (N21D) in the exon 2 of the human MDR1 gene encoding the P-glycoprotein."
Decleves X. , Chevillard S. , Charpentier C. , Vielh P. , Laplanche J.-L.
Hum. Mutat.15:486-486(2000) [PubMed] [Europe PMC] [Abstract]

"Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo."
Hoffmeyer S. , Burk O. , von Richter O. , Arnold H.P. , Brockmoeller J. , Johne A. , Cascorbi I. , Gerloff T. , Roots I. , Eichelbaum M. , Brinkmann U.
Proc. Natl. Acad. Sci. U.S.A.97:3473-3478(2000) [PubMed] [Europe PMC] [Abstract]

"Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects."
Cascorbi I. , Gerloff T. , Johne A. , Meisel C. , Hoffmeyer S. , Schwab M. , Schaeffeler E. , Eichelbaum M. , Brinkmann U. , Roots I.
Clin. Pharmacol. Ther.69:169-174(2001) [PubMed] [Europe PMC] [Abstract]

"Polymorphism of MDR1 gene in healthy Japanese subjects: a novel SNP with an amino acid substitution (Glu108Lys)."
Honda T. , Dan Y. , Koyabu N. , Ieiri I. , Otsubo K. , Higuchi S. , Ohtani H. , Sawada J.
Drug Metab. Pharmacokinet.17:479-481(2002) [PubMed] [Europe PMC] [Abstract]

"Twelve novel single nucleotide polymorphisms in ABCB1/MDR1 among Japanese patients with ventricular tachycardia who were administered amiodarone."
Itoda M. , Saito Y. , Komamura K. , Ueno K. , Kamakura S. , Ozawa S. , Sawada J.
Drug Metab. Pharmacokinet.17:566-571(2002) [PubMed] [Europe PMC] [Abstract]

"Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population."
Saito S. , Iida A. , Sekine A. , Miura Y. , Ogawa C. , Kawauchi S. , Higuchi S. , Nakamura Y.
J. Hum. Genet.47:38-50(2002) [PubMed] [Europe PMC] [Abstract]

"MDR1 Ala893 polymorphism is associated with inflammatory bowel disease."
Brant S.R. , Panhuysen C.I.M. , Nicolae D. , Reddy D.M. , Bonen D.K. , Karaliukas R. , Zhang L. , Swanson E. , Datta L.W. , Moran T. , Ravenhill G. , Duerr R.H. , Achkar J.-P. , Karban A.S. , Cho J.H.
Am. J. Hum. Genet.73:1282-1292(2003) [PubMed] [Europe PMC] [Abstract]

Brant S.R. , Panhuysen C.I.M. , Nicolae D. , Reddy D.M. , Bonen D.K. , Karaliukas R. , Zhang L. , Swanson E. , Datta L.W. , Moran T. , Ravenhill G. , Duerr R.H. , Achkar J.-P. , Karban A.S. , Cho J.H.
Am. J. Hum. Genet.74:1080-1080(2004)

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , Gazdar A.F. , Hartigan J. , Wu L. , Liu C. , Parmigiani G. , Park B.H. , Bachman K.E. , Papadopoulos N. , Vogelstein B. , Kinzler K.W. , Velculescu V.E. more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]