Med17 ELISA Kit for Mouse(Mus musculus) | EIAab.comMed17 ELISA Kit for Mouse(Mus musculus)

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Med17 (Gene name),

Mediator of RNA polymerase II transcription subunit 17 (Protein name ), MED17_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

Med17(Crsp6;Trap80);

Protein name:

Mediator of RNA polymerase II transcription subunit 17;

Alternative:

Mediator complex subunit 17;Cofactor required for Sp1 transcriptional activation subunit 6(CRSP complex subunit 6);Thyroid hormone receptor-associated protein complex 80 kDa component;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP. Interacts with STAT2 (By similarity). Interacts with GATA1 and PPARG.

Function:

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

649

Sequence:

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