MED22 ELISA Kit for Human(Homo sapiens) | EIAab.comMED22 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > MED22(Gene name) > Human

MED22 (Gene name),

Mediator of RNA polymerase II transcription subunit 22 (Protein name ), MED22_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

MED22(SURF5);

Protein name:

Mediator of RNA polymerase II transcription subunit 22;

Alternative:

Surfeit locus protein 5(Surf-5);Mediator complex subunit 22;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.

Function:

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

200

Sequence:

50:

100:

150:

200:

3D Structure:

N/A