MEF2A ELISA Kit for Pig(Sus scrofa) | EIAab.comMEF2A ELISA Kit for Pig(Sus scrofa)

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MEF2A (Gene name),

Myocyte-specific enhancer factor 2A (Protein name ), MEF2A_PIG from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

MEF2A;

Protein name:

Myocyte-specific enhancer factor 2A;

Alternative:

Organism:

Pig (Sus scrofa).

General Annotation

Sub Unit:

Binds DNA as a homo- or heterodimer (By similarity). Dimerizes with MEF2D. Interacts with HDAC7. Interacts with PIAS1; the interaction enhances sumoylation. Interacts with HDAC4, HDAC9 and SLC2A4RG. Interacts (via the N-terminal) with MAPK7; the interaction results in the phosphorylation and transcriptional activity of MEF2A.

Function:

Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

507

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

507:

RMDAWVT

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF12347

SMR:

A2ICN5

UniGene:

Ssc.19462

KEGG:

ssc:100037273

String:

A2ICN5

Uniprot:

A2ICN5

FOR

ELISA Kit for Pig Myocyte-specific enhancer factor 2A

CLIA Kit for Pig Myocyte-specific enhancer factor 2A

Polyclonal Antibody for Pig Myocyte-specific enhancer factor 2A

Monoclonal Antibody for Pig Myocyte-specific enhancer factor 2A

Protein for Pig Myocyte-specific enhancer factor 2A

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning and expression roles of the MEF2A gene in pig."
Yang L. , Gao Z. , Liu D.
Submitted (2007-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3)

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