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Index > Protein center > MFGE8(Gene name) > Human
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  • MFGE8 (Gene name),
  • Lactadherin (Protein name ),  MFGM_HUMAN from NCBI database.
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  • General Annotation
  • |
  • Antigen Annotation
  • |
  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    MFGE8;
    Protein name:
    Lactadherin;
    Alternative:
    HMFG;Breast epithelial antigen BA46;Milk fat globule-EGF factor 8(MFG-E8);MFGM;SED1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Function:
    Medin is the main constituent of aortic medial amyloid.
    Subcellular Location:
    Membrane Peripheral membrane protein Secreted
    Protein Attributes:
    Sequence length:
    387
    Sequence:
    50:
    MPRPRLLAAL | CGALLCAPSL | LVALDICSKN | PCHNGGLCEE | ISQEVRGDVF | 
    100:
    PSYTCTCLKG | YAGNHCETKC | VEPLGMENGN | IANSQIAASS | VRVTFLGLQH | 
    150:
    WVPELARLNR | AGMVNAWTPS | SNDDNPWIQV | NLLRRMWVTG | VVTQGASRLA | 
    200:
    SHEYLKAFKV | AYSLNGHEFD | FIHDVNKKHK | EFVGNWNKNA | VHVNLFETPV | 
    250:
    EAQYVRLYPT | SCHTACTLRF | ELLGCELNGC | ANPLGLKNNS | IPDKQITASS | 
    300:
    SYKTWGLHLF | SWNPSYARLD | KQGNFNAWVA | GSYGNDQWLQ | VDLGSSKEVT | 
    350:
    GIITQGARNF | GSVQFVASYK | VAYSNDSANW | TEYQDPRTGS | SKIFPGNWDN | 
    387:
    HSHKKNLFET | PILARYVRIL | PVAWHNRIAL | RLELLGC
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    KEGG:
    MIM:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Lactadherin
    Cat.:
    E2304m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Lactadherin
    Cat.:
    E2304b
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Lactadherin
    Cat.:
    E2304r
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Lactadherin
    Cat.:
    E2304h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Lactadherin
    Cat.:
    E2304p
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Lactadherin
    Cat.:
    U2304h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    CLIA Kit for Human Lactadherin
    Cat.:
    U2304p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Lactadherin
    Cat.:
    U2304r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Lactadherin
    Cat.:
    U2304b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Lactadherin
    Cat.:
    U2304m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Lactadherin
    Cat.:
    P2304Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Lactadherin
    Cat.:
    P2304Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Lactadherin
    Polyclonal Antibody for Human Lactadherin
    Polyclonal Antibody for Human Lactadherin
    Cat.:
    P2304Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Lactadherin
    Monoclonal Antibody for Human Lactadherin
    Monoclonal Antibody for Human Lactadherin
    Monoclonal Antibody for Human Lactadherin
    Monoclonal Antibody for Human Lactadherin
    Protein for Human Lactadherin
    Protein for Human Lactadherin
    Protein for Human Lactadherin
    Protein for Human Lactadherin
    Protein for Human Lactadherin

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    Precision
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    Linearity
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    References
    1. 1.
      "Cloning and sequence analysis of human breast epithelial antigen BA46 reveals an RGD cell adhesion sequence presented on an epidermal growth factor-like domain."
      Couto J.R. , Taylor M.R. , Godwin S.G. , Ceriani R.L. , Peterson J.A.
      DNA Cell Biol.15:281-286(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Mammary carcinoma.
      tissue: Mammary gland.
    2. 2.
      "Characterization of human epididymal protein."
      Sivashanmugam P. , Richardson R.T. , Hamil K.G. , Hall S.H. , French F.S. , O'Rand M.G.
      Submitted (2002-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT LEU-76
    5. 5.
      Suzuki Y. , Sugano S. , Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S.
      Submitted (2005-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT LEU-76
      tissue: Dermoid cancer.
      tissue: Pancreas.
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Retina.
    7. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 9.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      tissue: Skin.
    9. 10.
      "A Mr 46,000 human milk fat globule protein that is highly expressed in human breast tumors contains factor VIII-like domains."
      Larocca D. , Peterson J.A. , Urrea R. , Kuniyoshi J. , Bistrain A.M. , Ceriani R.L.
      Cancer Res.51:4994-4998(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 170-387
      tissue: Mammary gland.
    10. 11.
      "Isolation and characterization of full and truncated forms of human breast carcinoma protein BA46 from human milk fat globule membranes."
      Giuffrida M.G. , Cavaletto M. , Giunta C. , Conti A. , Godovac-Zimmermann J.
      J. Protein Chem.17:143-148(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE;CHARACTERIZATION
      tissue: Milk.
    11. 12.
      "Medin: an integral fragment of aortic smooth muscle cell-produced lactadherin forms the most common human amyloid."
      Haeggqvist B. , Naeslund J. , Sletten K. , Westermark G.T. , Mucchiano G. , Tjernberg L.O. , Nordstedt C. , Engstroem U. , Westermark P.
      Proc. Natl. Acad. Sci. U.S.A.96:8669-8674(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 268-317;IDENTIFICATION OF MEDIN
    12. 13.
      "Lactadherin (formerly BA46), a membrane-associated glycoprotein expressed in human milk and breast carcinomas, promotes Arg-Gly-Asp (RGD)-dependent cell adhesion."
      Taylor M.R. , Couto J.R. , Scallan C.D. , Ceriani R.L. , Peterson J.A.
      DNA Cell Biol.16:861-869(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
    13. 14.
      "Identification of N-linked glycoproteins in human milk by hydrophilic interaction liquid chromatography and mass spectrometry."
      Picariello G. , Ferranti P. , Mamone G. , Roepstorff P. , Addeo F.
      Proteomics8:3833-3847(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-228; ASN-238; ASN-325; ASN-329 AND ASN-350
      tissue: Milk.
    14. 15.
      "SED1/MFG-E8: a bi-motif protein that orchestrates diverse cellular interactions."
      Raymond A. , Ensslin M.A. , Shur B.D.
      J. Cell. Biochem.106:957-966(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
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