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Index > Protein center > Mgmt(Gene name) > Mouse
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  • Mgmt (Gene name),
  • Methylated-DNA--protein-cysteine methyltransferase (Protein name ),  MGMT_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Mgmt;
    Protein name:
    Methylated-DNA--protein-cysteine methyltransferase;
    Alternative:
    O-6-methylguanine-DNA-alkyltransferase;6-O-methylguanine-DNA methyltransferase(MGMT);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    211
    Sequence:
    50:
    MAETCKMKYS | VLDSPLGKME | LSGCERGLHG | IRLLSGKTPN | TDPTEAPATP | 
    100:
    EVLGGPEGVP | EPLVQCTAWL | EAYFREPAAT | EGLPLPALHH | PVFQQDSFTR | 
    150:
    QVLWKLLKVV | KFGETVSYQQ | LAALAGNPKA | ARAVGGAMRS | NPVPILIPCH | 
    200:
    RVVRSDGAIG | HYSGGGQAVK | EWLLAHEGIP | TGQPASKGLG | LTGTWLKSSF | 
    211:
    ESTSSEPSGR | N
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    String:
    UniGene:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Methylated-DNA--protein-cysteine methyltransferase
    Cat.:
    E2027h
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    ELISA Kit for Mouse Methylated-DNA--protein-cysteine methyltransferase
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    ELISA Kit for Mouse Methylated-DNA--protein-cysteine methyltransferase
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    E2027d
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    ELISA Kit for Mouse Methylated-DNA--protein-cysteine methyltransferase
    Cat.:
    E2027r
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    Packing:
    96T
    ELISA Kit for Mouse Methylated-DNA--protein-cysteine methyltransferase
    Cat.:
    E2027m
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    Packing:
    96T
    CLIA Kit for Mouse Methylated-DNA--protein-cysteine methyltransferase
    Cat.:
    U2027r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Methylated-DNA--protein-cysteine methyltransferase
    Cat.:
    U2027m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Methylated-DNA--protein-cysteine methyltransferase
    Cat.:
    U2027d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Methylated-DNA--protein-cysteine methyltransferase
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Methylated-DNA--protein-cysteine methyltransferase
    Cat.:
    U2027h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Methylated-DNA--protein-cysteine methyltransferase
    Polyclonal Antibody for Mouse Methylated-DNA--protein-cysteine methyltransferase
    Cat.:
    P2027Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Methylated-DNA--protein-cysteine methyltransferase
    Cat.:
    P2027Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Methylated-DNA--protein-cysteine methyltransferase
    Cat.:
    P2027Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Methylated-DNA--protein-cysteine methyltransferase
    Monoclonal Antibody for Mouse Methylated-DNA--protein-cysteine methyltransferase
    Monoclonal Antibody for Mouse Methylated-DNA--protein-cysteine methyltransferase
    Monoclonal Antibody for Mouse Methylated-DNA--protein-cysteine methyltransferase
    Monoclonal Antibody for Mouse Methylated-DNA--protein-cysteine methyltransferase
    Monoclonal Antibody for Mouse Methylated-DNA--protein-cysteine methyltransferase
    Protein for Mouse Methylated-DNA--protein-cysteine methyltransferase
    Protein for Mouse Methylated-DNA--protein-cysteine methyltransferase
    Protein for Mouse Methylated-DNA--protein-cysteine methyltransferase
    Protein for Mouse Methylated-DNA--protein-cysteine methyltransferase
    Protein for Mouse Methylated-DNA--protein-cysteine methyltransferase

    R&D Technical Data
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    Precision
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    Linearity
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    References
    1. 1.
      "Characterization of cDNA encoding mouse DNA repair protein O6-methylguanine-DNA methyltransferase and high-level expression of the wild-type and mutant proteins in Escherichia coli."
      Shiota S. , von Wronski M.A. , Tano K. , Bigner D.D. , Brent T.P. , Mitra S.
      Biochemistry31:1897-1903(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
    2. 2.
      "MGMT sequence of B6 and C3H mice."
      Shimada Y. , Kakinuma S. , Kubo A. , Nishimura M.
      Submitted (2002-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C3H.
      strain: C57BL/6.
      tissue: Thymus.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N-3.
      tissue: Mammary gland.
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