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Index > Protein center > MIER1(Gene name) > Human
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  • MIER1 (Gene name),
  • Mesoderm induction early response protein 1 (Protein name ),  MIER1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    MIER1(KIAA1610);
    Protein name:
    Mesoderm induction early response protein 1(Early response 1;Er1;Mi-er1;hMi-er1);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with HDAC1.
    Function:
    Transcriptional repressor of a number of genes including Sp1 target genes.
    Subcellular Location:
    Isoform 6 Cytoplasm
    Protein Attributes:
    Sequence length:
    536
    Sequence:
    50:
    MLKMCIRCLC | LIGLQTVCGL | FSCQITQPSV | ESSSPGGSAT | SDDHEFDPSA | 
    100:
    DMLVHDFDDE | RTLEEEEMME | GETNFSSEIE | DLAREGDMPI | HELLSLYGYG | 
    150:
    STVRLPEEDE | EEEEEEEEGE | DDEDADNDDN | SGCSGENKEE | NIKDSSGQED | 
    200:
    ETQSSNDDPS | QSVASQDAQE | IIRPRRCKYF | DTNSEVEEES | EEDEDYIPSE | 
    250:
    DWKKEIMVGS | MFQAEIPVGI | CRYKENEKVY | ENDDQLLWDP | EYLPEDKVII | 
    300:
    FLKDASRRTG | DEKGVEAIPE | GSHIKDNEQA | LYELVKCNFD | TEEALRRLRF | 
    350:
    NVKAAREELS | VWTEEECRNF | EQGLKAYGKD | FHLIQANKVR | TRSVGECVAF | 
    400:
    YYMWKKSERY | DFFAQQTRFG | KKKYNLHPGV | TDYMDRLLDE | SESAASSRAP | 
    450:
    SPPPTASNSS | NSQSEKEDGT | VSTANQNGVS | SNGPGEILNK | EEVKVEGLHI | 
    500:
    NGPTGGNKKP | LHADMDTNGY | ETDNLTTDPK | LAHMTARNEN | DFDEKSERPA | 
    536:
    KRRRVNSNGK | ESPGSSEFFQ | EAVSHGKFEE | LENTDD
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    UniGene:
    KEGG:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Early response 1
    ELISA Kit for Human Early response 1
    ELISA Kit for Human Early response 1
    CLIA Kit for Human Early response 1
    CLIA Kit for Human Early response 1
    CLIA Kit for Human Early response 1
    Polyclonal Antibody for Human Early response 1
    Polyclonal Antibody for Human Early response 1
    Polyclonal Antibody for Human Early response 1
    Monoclonal Antibody for Human Early response 1
    Monoclonal Antibody for Human Early response 1
    Monoclonal Antibody for Human Early response 1
    Protein for Human Early response 1
    Protein for Human Early response 1
    Protein for Human Early response 1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Genomic organization of the human mi-er1 gene and characterization of alternatively spliced isoforms: regulated use of a facultative intron determines subcellular localization."
      Paterno G.D. , Ding Z. , Yew Y.-Y. , Nash G.W. , Mercer F.C. , Gillespie L.L.
      Gene295:79-88(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3; 4; 5 AND 6);TISSUE SPECIFICITY;SUBCELLULAR LOCATION
    2. 2.
      Paterno G.D. , Ding Z. , Lew Y.Y. , Nash G.W. , Mercer F.C. , Gillespie L.L.
      Submitted (2011-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-204 (ISOFORMS 1/6)
      tissue: Testis.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3 AND 7)
      tissue: Retina.
      tissue: Skeletal muscle.
    5. 5.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 8; 9 AND 10);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-199 (ISOFORMS 1/6)
      tissue: Lung.
      tissue: Testis.
    8. 8.
      "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T. , Kikuno R. , Nakayama M. , Hirosawa M. , Ohara O.
      DNA Res.7:273-281(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 29-512 (ISOFORMS 1/2/3/7)
    9. 9.
      "Human MI-ER1 alpha and beta function as transcriptional repressors by recruitment of histone deacetylase 1 to their conserved ELM2 domain."
      Ding Z. , Gillespie L.L. , Paterno G.D.
      Mol. Cell. Biol.23:250-258(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH HDAC1;MUTAGENESIS OF TRP-214 AND 227-PHE--LEU-228
    10. 10.
      "Molecular cloning of human er1 cDNA and its differential expression in breast tumours and tumour-derived cell lines."
      Paterno G.D. , Mercer F.C. , Chayter J.J. , Yang X. , Robb J.D. , Gillespie L.L.
      Gene222:77-82(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    11. 11.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-488;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    12. 12.
      "CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation."
      Mulligan P. , Westbrook T.F. , Ottinger M. , Pavlova N. , Chang B. , Macia E. , Shi Y.J. , Barretina J. , Liu J. , Howley P.M. , Elledge S.J. , Shi Y.
      Mol. Cell32:718-726(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A COMPLEX WITH CDYL; MIER2; HDAC1 AND HDAC2
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-155; SER-160; SER-166; SER-483 AND SER-488;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    14. 14.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-160 AND SER-166;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    15. 15.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-166 AND SER-483;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    16. 16.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    17. 17.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-160; SER-166; SER-483 AND SER-488;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    18. 18.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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