Protein name:
    Mitochondrial Rho GTPase 1 (MIRO-1;hMiro-1) ;
    
    Alternative:
    
    Ras homolog gene family member T1 ;Rac-GTP-binding protein-like protein ;
    
    
 
    Organism:
        
        
        
        
        
        
    
        Human  (Homo sapiens).  
    
 
General Annotation
    Sub Unit:
    Interacts with the kinesin-binding proteins TRAK1/OIP106 and TRAK2/GRIF1, forming a link between mitochondria and the trafficking apparatus of the microtubules.
    
 
    Function:
    Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.
    
 
    
        
        Subcellular Location:
        
    
     
     
      Mitochondrion outer membrane  
      Single-pass type IV membrane protein 
     
  
    
 
    
    Protein Attributes:
    
    50:
    MKKDVRILLV |  GEPRVGKTSL |  IMSLVSEEFP |  EEVPPRAEEI |  TIPADVTPER |  
    
 
    100:
    VPTHIVDYSE |  AEQSDEQLHQ |  EISQANVICI |  VYAVNNKHSI |  DKVTSRWIPL |  
    
 
    150:
    INERTDKDSR |  LPLILVGNKS |  DLVEYSSMET |  ILPIMNQYTE |  IETCVECSAK |  
    
 
    200:
    NLKNISELFY |  YAQKAVLHPT |  GPLYCPEEKE |  MKPACIKALT |  RIFKISDQDN |  
    
 
    250:
    DGTLNDAELN |  FFQRICFNTP |  LAPQALEDVK |  NVVRKHISDG |  VADSGLTLKG |  
    
 
    300:
    FLFLHTLFIQ |  RGRHETTWTV |  LRRFGYDDDL |  DLTPEYLFPL |  LKIPPDCTTE |  
    
 
    350:
    LNHHAYLFLQ |  STFDKHDLDR |  DCALSPDELK |  DLFKVFPYIP |  WGPDVNNTVC |  
    
 
    400:
    TNERGWITYQ |  GFLSQWTLTT |  YLDVQRCLEY |  LGYLGYSILT |  EQESQASAVT |  
    
 
    450:
    VTRDKKIDLQ |  KKQTQRNVFR |  CNVIGVKNCG |  KSGVLQALLG |  RNLMRQKKIR |  
    
 
    500:
    EDHKSYYAIN |  TVYVYGQEKY |  LLLHDISESE |  FLTEAEIICD |  VVCLVYDVSN |  
    
 
    550:
    PKSFEYCARI |  FKQHFMDSRI |  PCLIVAAKSD |  LHEVKQEYSI |  SPTDFCRKHK |  
    
 
    600:
    MPPPQAFTCN |  TADAPSKDIF |  VKLTTMAMYP |  HVTQADLKSS |  TFWLRASFGA |  
    
 
    618:
    TVFAVLGFAM |  YKALLKQR
    
 
      Vaild Sequence:
    
 
Related Databases
Uniprot:
 
 
    
        
        ELISA Kit
         
        
        CLIA Kit
         
        
        Polyclonal Antibody
         
        
        Monoclonal Antibody
         
        
        Protein
         
        
     
FOR
    
        
        Human
         
        
        Mouse
         
        
        Chicken
         
        
        Bovine
         
        
     
    
        ELISA Kit for Human MIRO-1
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        ELISA Kit for Human MIRO-1
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        ELISA Kit for Human MIRO-1
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        ELISA Kit for Human MIRO-1
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Human MIRO-1
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Human MIRO-1
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Human MIRO-1
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Human MIRO-1
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human MIRO-1
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human MIRO-1
        
     
    
    
    
    
   
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human MIRO-1
        
     
    
    
    
    
   
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human MIRO-1
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human MIRO-1
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human MIRO-1
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human MIRO-1
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human MIRO-1
        
     
    
    
    
    
    
    
 
 
 
 
 
 
 
 
    R&D Technical Data
    
    
    
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    Precision
    
    
    
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    Recovery
    
    
    
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    Linearity
    
    
    
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    References
    
    
        
            
        
            
                1.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3) 
                    
                    
                 
             
         
            
        
            
                2.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;MUTAGENESIS OF PRO-13 AND THR-18 
                    
                    
                 
             
         
            
        
            
                3.
                
                    
                        
                            "Cloning a novel Rac-GTP binding protein-like gene from human fetal brain." 
                        
                        
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Xie Y. 
                        ,
                            
Mao Y. 
                        
                        
                        
                            Submitted (2002-04) to the EMBL/GenBank/DDBJ databases
                        
                        
                    
 
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3) 
                    
                    
                    tissue :
                    
Fetal brain .  
             
         
            
        
            
                4.
                
                    
                        
                            "Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs." 
                        
                        
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                              more...   
                             
                        
                        
                        
                            Genome Res.11:422-435(2001)
                         
                        
                        
                        [
PubMed ]
                        [
Europe PMC ]
                        [
Abstract ]
                        
                    
 
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4) 
                    
                    
                    tissue :
                    
Uterus .  
             
         
            
        
            
                5.
                
                    
                        
                            "Complete sequencing and characterization of 21,243 full-length human cDNAs." 
                        
                        
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                        ,
                            
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                              more...   
                             
                        
                        
                        
                            Nat. Genet.36:40-45(2004)
                         
                        
                        
                        [
PubMed ]
                        [
Europe PMC ]
                        [
Abstract ]
                        
                    
 
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 134-618 (ISOFORM 1);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 157-618 (ISOFORM 3) 
                    
                    
                    tissue :
                    
Amygdala . tissue :
                    
Placenta . tissue :
                    
Teratocarcinoma .  
             
         
            
        
            
                6.
                
                    
                        
                            "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." 
                        
                        
                            Zody M.C. 
                        ,
                            
Garber M. 
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Adams D.J. 
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Sharpe T. 
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Young S.K. 
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Bi W. 
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Bloom T. 
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Bugalter B.E. 
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Butler J. 
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Chang J.L. 
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                            Chen C.-K. 
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                            FitzGerald M. 
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                            Gilbert J. 
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                            Gibson R. 
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                            Nature440:1045-1049(2006)
                         
                        
                        
                        [
PubMed ]
                        [
Europe PMC ]
                        [
Abstract ]
                        
                    
 
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] 
                    
                    
                 
             
         
            
        
            
                7.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 5);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 18-618 (ISOFORM 2);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 90-550 (ISOFORM 6) 
                    
                    
                    tissue :
                    
Brain . tissue :
                    
Lung . tissue :
                    
Testis . tissue :
                    
Uterus .  
             
         
            
        
            
                8.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for MUTAGENESIS OF PRO-13 
                    
                    
                 
             
         
            
        
            
                9.
                
                    
                    
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                        Cited for FUNCTION;INTERACTION WITH TRAK1 AND TRAK2;MUTAGENESIS OF PRO-13; THR-18; GLU-208; GLU-328; LYS-427 AND SER-432 
                    
                    
                 
             
         
            
        
            
                10.
                
                    
                    
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                        Cited for SUBCELLULAR LOCATION 
                    
                    
                 
             
         
            
        
            
                11.
                
                    
                    
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                        Cited for IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS] 
                    
                    
                 
             
         
            
        
            
                12.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for UBIQUITINATION;DEUBIQUITINATION