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Index > Protein center > Mlkl(Gene name) > Mouse
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  • Mlkl (Gene name),
  • Mixed lineage kinase domain-like protein (Protein name ),  MLKL_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Mlkl;
    Protein name:
    Mixed lineage kinase domain-like protein;
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    N/A
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    472
    Sequence:
    50:
    MDKLGQIIKL | GQLIYEQCEK | MKYCRKQCQR | LGNRVHGLLQ | PLQRLQAQGK | 
    100:
    KNLPDDITAA | LGRFDEVLKE | ANQQIEKFSK | KSHIWKFVSV | GNDKILFHEV | 
    150:
    NEKLRDVWEE | LLLLLQVYHW | NTVSDVSQPA | SWQQEDRQDA | EEDGNENMKV | 
    200:
    ILMQLQISVE | EINKTLKQCS | LKPTQEIPQD | LQIKEIPKEH | LGPPWTKLKT | 
    250:
    SKMSTIYRGE | YHRSPVTIKV | FNNPQAESVG | IVRFTFNDEI | KTMKKFDSPN | 
    300:
    ILRIFGICID | QTVKPPEFSI | VMEYCELGTL | RELLDREKDL | TMSVRSLLVL | 
    350:
    RAARGLYRLH | HSETLHRNIS | SSSFLVAGGY | QVKLAGFELS | KTQNSISRTA | 
    400:
    KSTKAERSSS | TIYVSPERLK | NPFCLYDIKA | EIYSFGIVLW | EIATGKIPFE | 
    450:
    GCDSKKIREL | VAEDKKQEPV | GQDCPELLRE | IINECRAHEP | SQRPSVDGRS | 
    472:
    LSGRERILER | LSAVEESTDK | KV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Mixed lineage kinase domain-like protein
    Cat.:
    E1747h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse Mixed lineage kinase domain-like protein
    Cat.:
    E1747m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Mixed lineage kinase domain-like protein
    Cat.:
    U1747m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Mixed lineage kinase domain-like protein
    Cat.:
    U1747h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Mixed lineage kinase domain-like protein
    Cat.:
    P1747Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Mixed lineage kinase domain-like protein
    Cat.:
    P1747Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Mixed lineage kinase domain-like protein
    Monoclonal Antibody for Mouse Mixed lineage kinase domain-like protein
    Protein for Mouse Mixed lineage kinase domain-like protein
    Protein for Mouse Mixed lineage kinase domain-like protein

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      strain: C57BL/6J.
      strain: NOD.
      tissue: Cecum.
      tissue: Dendritic cell.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      strain: FVB/N.
      tissue: Mammary gland.
    3. 3.
      "Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase."
      Sun L. , Wang H. , Wang Z. , He S. , Chen S. , Liao D. , Wang L. , Yan J. , Liu W. , Lei X. , Wang X.
      Cell148:213-227(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RIPK3
    4. 4.
      "Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis."
      Wu J. , Huang Z. , Ren J. , Zhang Z. , He P. , Li Y. , Ma J. , Chen W. , Zhang Y. , Zhou X. , Yang Z. , Wu S.Q. , Chen L. , Han J.
      Cell Res.23:994-1006(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;DISRUPTION PHENOTYPE;FUNCTION
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    6. 6.
      "Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling."
      Chen W. , Zhou Z. , Li L. , Zhong C.Q. , Zheng X. , Wu X. , Zhang Y. , Ma H. , Huang D. , Li W. , Xia Z. , Han J.
      J. Biol. Chem.288:16247-16261(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RIPK3
    7. 7.
      "Structural insights into RIP3-mediated necroptotic signaling."
      Xie T. , Peng W. , Yan C. , Wu J. , Gong X. , Shi Y.
      Cell Rep.5:70-78(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF 182-472 IN COMPLEX WITH RIPK3;INTERACTION WITH RIPK3;PHOSPHORYLATION AT SER-345; SER-347; THR-349 AND SER-352;MUTAGENESIS OF SER-404 AND 404-SER-LYS-405
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS);ATP-BINDING;INTERACTION WITH RIPK3;PHOSPHORYLATION AT SER-345; SER-347 AND THR-349;MUTAGENESIS OF LYS-219; GLU-239; LEU-280; GLN-343; SER-345 AND PHE-385;DISRUPTION PHENOTYPE;FUNCTION
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