MMP12 ELISA Kit for Human(Homo sapiens) | EIAab.comMMP12 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > MMP12(Gene name) > Human

MMP12 (Gene name),

Macrophage metalloelastase (Protein name ), MMP12_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (3)

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Gene name:

MMP12(HME);

Protein name:

Macrophage metalloelastase(MME);

Alternative:

Matrix metalloproteinase-12(MMP-12);Macrophage elastase(ME;hME);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.

Subcellular Location:

Secreted extracellular space extracellular matrix

Protein Attributes:

Sequence length:

470

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

470:

YDFLLQRITK | TLKSNSWFGC |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.1695

STRING:

9606.ENSP00000320664

Pfam:

PF00045

SMR:

P39900

KEGG:

hsa:4321

String:

P39900

MIM:

601046

Uniprot:

P39900

FOR

ELISA Kit for Human MME

Cat.:

E0402h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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ELISA Kit for Human MME

Cat.:

E0402m

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Human MME

MSDS:

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ELISA Kit for Human MME

Cat.:

E0402r

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Packing:

96T

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CLIA Kit for Human MME

Cat.:

U0402r

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human MME

Cat.:

U0402m

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human MME

Cat.:

U0402Rb

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human MME

Cat.:

U0402h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human MME

Cat.:

P0402Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human MME

Cat.:

P0402Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human MME

Cat.:

P0402Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human MME

Protein for Human MME

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Citations

[1].

"The role of MMP-12 gene polymorphism − 82 A-to-G (rs2276109) in immunopathology of COPD in polish patients: a case control study"

I Gilowska, E Majorczyk, K Bogacz, et al.

From:BMC Medical Genetics

[2].

"Identification of potential serum biomarkers for gastric cancer by a novel computational method, multiple normal tissues corrected differential..."

Mirang Kim, Hyun Ja Kim, Bo Youl Choi, Jeong-Hwan Kim, Kyu-Sang Song, Seung-Moo Noh, Jin Cheon Kim, Dong Soo Han, Seon-Young Kim, Yong Sung Kim

From:Clinica Chimica Acta

[3].

"Expression of matrix metalloproteinase-12 in aortic dissection"

Y Song, Y Xie, F Liu, et al.

From:BMC Cardiovascular Disorders

References

1.

"Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages."
Shapiro S.D. , Kobayashi D.K. , Ley T.J.
J. Biol. Chem.268:23824-23829(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Alveolar macrophage.
2.

NIEHS SNPs program
Submitted (2004-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS SER-357 AND ARG-469
3.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Esophagus.
4.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT SER-357
6.

"Hydrolysis of a broad spectrum of extracellular matrix proteins by human macrophage elastase."
Gronski T.J. Jr. , Martin R.L. , Kobayashi D.K. , Walsh B.C. , Holman M.C. , Huber M. , Van Wart H.E. , Shapiro S.D.
J. Biol. Chem.272:12189-12194(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
7.

"Substrate specificity determinants of human macrophage elastase (MMP-12) based on the 1.1 A crystal structure."
Lang R. , Kocourek A. , Braun M. , Tschesche H. , Huber R. , Bode W. , Maskos K.
J. Mol. Biol.312:731-742(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.09 ANGSTROMS) OF 106-263
8.

"Crystal structure of human macrophage elastase (MMP-12) in complex with a hydroxamic acid inhibitor."
Nar H. , Werle K. , Bauer M.M.T. , Dollinger H. , Jung B.
J. Mol. Biol.312:743-751(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS) OF 100-280

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