MMP14 ELISA Kit for Human(Homo sapiens) | EIAab.comMMP14 ELISA Kit for Human(Homo sapiens)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > MMP14(Gene name) > Human

MMP14 (Gene name),

Matrix metalloproteinase-14 (Protein name ), MMP14_HUMAN from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

MMP14;

Protein name:

Matrix metalloproteinase-14(MMP-14);

Alternative:

Membrane-type matrix metalloproteinase 1(MT-MMP 1;MTMMP1);MMP-X1;Membrane-type-1 matrix metalloproteinase(MT1-MMP;MT1MMP);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Function:

Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7.

Subcellular Location:

Membrane Single-pass type I membrane protein Melanosome Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Protein Attributes:

Sequence length:

582

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

582:

LVLAVGLAVF | FFRRHGTPRR | LLYCQRSLLD | KV

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

SMR:

P50281

STRING:

9606.ENSP00000308208

UniGene:

Hs.2399

Pfam:

PF11857

MIM:

277950

KEGG:

hsa:4323

String:

P50281

MIM:

600754

Uniprot:

P50281

FOR

ELISA Kit for Human MMP-14

Cat.:

E2056h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human MMP-14

Cat.:

E2056p

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human MMP-14

Cat.:

E2056r

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Human MMP-14

MSDS:

Please sign in first.

ELISA Kit for Human MMP-14

Cat.:

E2056b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Human MMP-14

Cat.:

E2056m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human MMP-14

Cat.:

U2056b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human MMP-14

Cat.:

U2056p

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human MMP-14

Cat.:

U2056h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human MMP-14

Cat.:

U2056r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human MMP-14

Cat.:

U2056m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human MMP-14

MSDS:

Please sign in first.

Polyclonal Antibody for Human MMP-14

Cat.:

P2056Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human MMP-14

Cat.:

P2056Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Human MMP-14

Cat.:

P2056Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human MMP-14

Protein for Human MMP-14

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"A matrix metalloproteinase expressed on the surface of invasive tumour cells."
Sato H. , Takino T. , Okada Y. , Cao J. , Shinagawa A. , Yamamoto E. , Seiki M.
Nature370:61-65(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT SER-8
tissue: Placenta.
2.

"Cloning of a human gene potentially encoding a novel matrix metalloproteinase having a C-terminal transmembrane domain."
Takino T. , Sato H. , Yamamoto E. , Seiki M.
Gene155:293-298(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT SER-8
tissue: Placenta.
3.

"Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas."
Okada A. , Bellocq J.-P. , Rouyer N. , Chenard M.P. , Rio M.C. , Chambon P. , Basset P.
Proc. Natl. Acad. Sci. U.S.A.92:2730-2734(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT SER-8
4.

"cDNA sequence and mRNA tissue distribution of a novel human matrix metalloproteinase with a potential transmembrane segment."
Will H. , Hinzmann B.
Eur. J. Biochem.231:602-608(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT SER-8
tissue: Lung.
5.

Luo G.-X. , Reisfeld R.A. , Strongin A.Y.
Submitted (1995-11) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
6.

"Regulation of membrane-type matrix metalloproteinase-1 expression by growth factors and phorbol 12-myristate 13-acetate."
Lohi J.L. , Westermarck J. , Kaehaeri V.M. , Keski-Oja J.
Eur. J. Biochem.239:239-247(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
7.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT SER-8
tissue: Tongue.
8.

NIEHS SNPs program
Submitted (2004-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS THR-4; LYS-6; SER-8; VAL-233; ASN-273; TRP-302 AND ILE-355
9.

"The DNA sequence and analysis of human chromosome 14."
Heilig R. , Eckenberg R. , Petit J.-L. , Fonknechten N. , Da Silva C. , Cattolico L. , Levy M. , Barbe V. , De Berardinis V. , Ureta-Vidal A. , Pelletier E. , Vico V. , Anthouard V. , Rowen L. , Madan A. , Qin S. , Sun H. , Du H. , more...
Nature421:601-607(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
10.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT SER-8
tissue: Skin.
11.

"Activation of a recombinant membrane type 1-matrix metalloproteinase (MT1-MMP) by furin and its interaction with tissue inhibitor of metalloproteinases (TIMP)-2."
Sato H. , Kinoshita T. , Takino T. , Nakayama K. , Seiki M.
FEBS Lett.393:101-104(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 112-116
12.

"Production and activation of matrix metalloproteinase-2 in proliferative diabetic retinopathy."
Noda K. , Ishida S. , Inoue M. , Obata K. , Oguchi Y. , Okada Y. , Ikeda E.
Invest. Ophthalmol. Vis. Sci.44:2163-2170(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN THE FORMATION OF THE FIBROVASCULAR TISSUES
13.

"Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes."
Chi A. , Valencia J.C. , Hu Z.-Z. , Watabe H. , Yamaguchi H. , Mangini N.J. , Huang H. , Canfield V.A. , Cheng K.C. , Yang F. , Abe R. , Yamagishi S. , Shabanowitz J. , Hearing V.J. , Wu C. , Appella E. , Hunt D.F.
J. Proteome Res.5:3135-3144(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]
tissue: Melanoma.
14.

"The E-cadherin-repressed hNanos1 gene induces tumor cell invasion by upregulating MT1-MMP expression."
Bonnomet A. , Polette M. , Strumane K. , Gilles C. , Dalstein V. , Kileztky C. , Berx G. , van Roy F. , Birembaut P. , Nawrocki-Raby B.
Oncogene27:3692-3699(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION;TISSUE SPECIFICITY
15.

"The Wnt/planar cell polarity protein-tyrosine kinase-7 (PTK7) is a highly efficient proteolytic target of membrane type-1 matrix metalloproteinase: implications in cancer and embryogenesis."
Golubkov V.S. , Chekanov A.V. , Cieplak P. , Aleshin A.E. , Chernov A.V. , Zhu W. , Radichev I.A. , Zhang D. , Dong P.D. , Strongin A.Y.
J. Biol. Chem.285:35740-35749(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
16.

"BST-2 binding with cellular MT1-MMP blocks cell growth and migration via decreasing MMP2 activity."
Gu G. , Zhao D. , Yin Z. , Liu P.
J. Cell. Biochem.113:1013-1021(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH BST2
17.

"A secreted tyrosine kinase acts in the extracellular environment."
Bordoli M.R. , Yum J. , Breitkopf S.B. , Thon J.N. , Italiano J.E. Jr. , Xiao J. , Worby C. , Wong S.K. , Lin G. , Edenius M. , Keller T.L. , Asara J.M. , Dixon J.E. , Yeo C.Y. , Whitman M.
Cell158:1033-1044(2014) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-399
18.

"Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor."
Fernandez-Catalan C. , Bode W. , Huber R. , Turk D. , Calvete J.J. , Lichte A. , Tschesche H. , Maskos K.
EMBO J.17:5238-5248(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.75 ANGSTROMS) OF 114-287 IN COMPLEX WITH TIMP2
19.

"Mutation of membrane type-1 metalloproteinase, MT1-MMP, causes the multicentric osteolysis and arthritis disease Winchester syndrome."
Evans B.R. , Mosig R.A. , Lobl M. , Martignetti C.R. , Camacho C. , Grum-Tokars V. , Glucksman M.J. , Martignetti J.A.
Am. J. Hum. Genet.91:572-576(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT WNCHRS ARG-17;CHARACTERIZATION OF VARIANT WNCHRS ARG-17

Product Feedback Wall

* Email:
*Comments: